Gene: Crybg1

Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
embryonic lethality prior to tooth bud stage Crybg1tm1b(KOMP)Wtsi HOM embryonic day 12.5 0.00
preweaning lethality, complete penetrance Crybg1tm1b(KOMP)Wtsi HOM n/a 0.00
abnormal neural tube closure Crybg1tm1b(KOMP)Wtsi HET embryonic day 9.5 0.00
abnormal hindbrain development Crybg1tm1b(KOMP)Wtsi HET embryonic day 9.5 0.00
abnormal eye morphology Crybg1tm1b(KOMP)Wtsi HET postnatal 0.00
hypoactivity Crybg1tm1b(KOMP)Wtsi HET postnatal 2.41×10-05
embryonic lethality prior to organogenesis Crybg1tm1b(KOMP)Wtsi HOM embryonic day 9.5 0.00
abnormal forebrain development Crybg1tm1b(KOMP)Wtsi HET embryonic day 9.5 0.00
abnormal midbrain development Crybg1tm1b(KOMP)Wtsi HET embryonic day 9.5 0.00
decreased prepulse inhibition Crybg1tm1b(KOMP)Wtsi HET postnatal 8.10×10-15
abnormal embryo size Crybg1tm1b(KOMP)Wtsi HET embryonic day 9.5 0.00

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Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

No Adult expression data was found for this gene.
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 2  (1/51)  (2/2) N/A
Brain 16  (6/485) N/A
Central nervous system ganglion 2  (1/51) N/A
Ear 16  (1/485)  (2/16) N/A
Embryo 16  (1/485)  (2/16) N/A
Eye 16  (1/485)  (2/16) N/A
Foot 16  (1/485) N/A
Forebrain 16  (1/485) N/A
Forelimb 16  (1/485) N/A
Gut 2  (1/50) N/A
Hand 16  (1/485) N/A
Head 16  (5/485) N/A
Heart 16  (1/485)  (2/16) N/A
Hindbrain 16  (6/485) N/A
Hindlimb 16  (1/485) N/A
Liver 16  (1/485) N/A
Lung 16  (1/485) N/A
Mandibular process 16  (1/485) N/A
Maxillary process 16  (1/485)  (2/16) N/A
Midbrain 16  (1/485) N/A
Nose 2  (1/51) N/A
Oral cavity 16  (1/485) N/A
Skeleton 2  (1/51) N/A
Skin 16  (1/485) N/A
Spinal cord 2  (1/50) N/A
Tail 16  (1/485) N/A
Tail somite 16  (1/485) N/A
Trachea 2  (1/50) N/A
Urinary system 2  (1/50)  (2/2) N/A

 Associated Images

X-ray: XRay Images Lateral Orientation
10 Images
Gross Pathology and Tissue Collection
9 Images
X-ray: XRay Images Dorso Ventral
10 Images
X-ray: XRay Images Skull Lateral Orientation
10 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
Eye Morphology: Images Ophthalmoscopy
6 Images
Eye Morphology: Images Slit Lamp
2 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Crybg1tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Crybg1tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice, Tissue

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