Genes Phenotypes

Gene: Trpc3

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Name
transient receptor potential cation channel, subfamily C, member 3
MGI ID
MGI:109526
Synonyms
Trp3 Trcp3 Trrp3
Viability
Homozygous - Lethal
View
N/A
Other links
MGI   Ensembl  
Significant phenotypes (19) Measurements chart (515) All data table (687)
Expression & images (101) Disease models (0) Order (2)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
increased startle reflex Trpc3Mwk HET postnatal 4.76×10-19
decreased body weight Trpc3Mwk HET postnatal 4.16×10-23
preweaning lethality, complete penetrance Trpc3tm1b(EUCOMM)Wtsi HOM n/a 0.00
hyperactivity Trpc3Mwk HET postnatal 4.95×10-05
decreased bone mineral density Trpc3Mwk HET postnatal 1.65×10-09
decreased circulating glycerol level Trpc3Mwk HET postnatal 2.32×10-05
limb grasping Trpc3Mwk HET postnatal 1.28×10-05
abnormal locomotor activation Trpc3Mwk HET postnatal 5.49×10-08
increased total body fat amount Trpc3Mwk HET postnatal 8.97×10-15
increased lean body mass Trpc3Mwk HET postnatal 2.91×10-06
decreased prepulse inhibition Trpc3Mwk HET postnatal 6.09×10-05
decreased circulating triglyceride level Trpc3Mwk HET postnatal 7.61×10-06
mammalian phenotype Trpc3Mwk HET postnatal 3.52×10-12
abnormal gait Trpc3Mwk HET postnatal 2.71×10-07
corneal vascularization Trpc3Mwk HET postnatal 3.21×10-05
abnormal forelimb morphology Trpc3Mwk HET postnatal 3.20×10-13
decreased lean body mass Trpc3Mwk HET postnatal 7.14×10-06
decreased circulating amylase level Trpc3Mwk HET postnatal 2.28×10-06
abnormal response to new environment Trpc3Mwk HET postnatal 5.87×10-05

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 4 No  (2/584) N/A
Aorta 4 No N/A
Bone 4 No N/A
Brain 4 No N/A
Brainstem 4 No N/A
Brown adipose tissue 4 No N/A
Cartilage tissue 4 No N/A
Cecum 4 No  (12/383) N/A
Cerebellum 4 No N/A
Cerebral cortex 4 No N/A
Chest bone 4 No N/A
Colon 4 No  (12/127) N/A
Cranium 4 No N/A
Diaphragm 4 No N/A
Duodenum 4 No  (2/127) N/A
Epididymis 4 No  (18/134) N/A
Esophagus 4 No  (7/415) N/A
Eye 4 No N/A
Gall bladder 4 No N/A
Gonadal fat pad 4 No N/A
Harderian gland 4 No N/A
Heart 4 No N/A
Hindlimb 4 No N/A
Hippocampus 4 No N/A
Hypothalamus 4 No N/A
Ileum 4 No  (14/127) N/A
Jejunum 4 No  (6/127) N/A
Kidney 4 No  (18/584) N/A
Large intestine 4 No  (10/584) N/A
Liver 4 No N/A
Lower urinary tract 4 No N/A
Lung 4 No N/A
Lymph node 4 No N/A
Main olfactory bulb 4 No N/A
Mammary gland 4 No N/A
Mesenteric adipose tissue 4 No N/A
Mesenteric lymph node 4 No N/A
Midbrain 4 No N/A
Olfactory lobe 4 No N/A
Oral epithelium 4 No N/A
Ovary 4 No  (1/584) N/A
Oviduct 4 No N/A
Pancreas 4 No  (5/584) N/A
Parathyroid gland 4 No N/A
Parotid gland 4 No N/A
Penis 4 No N/A
Peripheral nervous system 4 No N/A
Peyer's patch 4 No N/A
Pituitary gland 4 No N/A
Prostate gland 4 No  (12/584) N/A
Quadriceps 4 No N/A
Sciatic nerve 4 No N/A
Skeletal muscle 4 No N/A
Skin 4 No N/A
Small intestine 4 No  (9/584) N/A
Spinal cord 4 No N/A
Spleen 4 No  (2/584) N/A
Stomach 4 No  (12/584) N/A
Stomach pyloric region 4 No N/A
Striatum 4 No N/A
Sublingual gland 4 No N/A
Submandibular gland 4 No  (2/132) N/A
Testis 4 No  (2/584) N/A
Thalamus 4 No N/A
Thymus 4 No N/A
Thyroid gland 4 No  (15/584) N/A
Tongue 4 No  (5/127) N/A
Trachea 4 No N/A
Trigeminal V nerve 4 No N/A
Urinary bladder 4 No N/A
Uterus 4 No N/A
Vagina 4 No N/A
Vas deferens 4 No  (15/388) N/A
Vascular system 4 No N/A
Vesicular gland 4 No N/A
White adipose tissue 4 No N/A
LacZ Wholemount Images
Unassigned Top Level MA (72)
LacZ Section Images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 7  (6/485) N/A
Ear 7  (1/485) N/A
Embryo 7  (1/485)  Wholemount images
Eye 7  (1/485) N/A
Foot 7  (1/485) N/A
Forearm 7  (1/282) N/A
Forebrain 7  (1/485) N/A
Forelimb 7  (1/485) N/A
Hand 7  (1/485) N/A
Head 7  (5/485) N/A
Heart 7  (1/485) N/A
Hindbrain 7  (6/485) N/A
Hindlimb 7  (1/485) N/A
Liver 7  (1/485) N/A
Lower leg 7  (1/282) N/A
Lung 7  (1/485) N/A
Mandibular process 7  (1/485) N/A
Maxillary process 7  (1/485) N/A
Midbrain 7  (1/485) N/A
Oral cavity 7  (1/485) N/A
Skin 7  (1/485) N/A
Tail 7  (1/485) N/A
Tail somite 7  (1/485) N/A
Upper arm 7  (1/282) N/A
Upper leg 7  (1/282) N/A
embryo or Unassigned (6)
Embryo no expression
EMAPA:16039 embryo

 Associated Images

X-ray: XRay Images Dorso Ventral
10 Images
X-ray: XRay Images Lateral Orientation
10 Images
Adult LacZ: LacZ Images Wholemount
72 Images
Eye Morphology: Images Ophthalmoscopy
4 Images
Eye Morphology: Images Slit Lamp
1 Images
Embryo LacZ: LacZ images wholemount
6 Images

 Disease Models

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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Trpc3tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Trpc3tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice

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