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Genes Phenotypes

Gene: Trpc3

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Name
transient receptor potential cation channel, subfamily C, member 3
MGI ID
MGI:109526
Synonyms
Trp3 Trrp3 Trcp3
Viability
Homozygous - Lethal
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (18) Measurements chart (295) All data table (869)
Expression & images (101) Disease models (0) Order (2)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal forelimb morphology Trpc3Mwk HET Early adult 3.20×10-13
abnormal gait Trpc3Mwk HET Early adult 2.71×10-07
decreased circulating amylase level Trpc3Mwk HET Early adult 6.84×10-06
decreased circulating triglyceride level Trpc3Mwk HET Early adult 1.42×10-05
increased startle reflex Trpc3Mwk HET Early adult 3.27×10-07
increased total body fat amount Trpc3Mwk HET Early adult 3.84×10-07
increased hematocrit Trpc3Mwk HET   Early adult 4.71×10-07
preweaning lethality, complete penetrance Trpc3tm1b(EUCOMM)Wtsi HOM   Early adult 0.00
hyperactivity Trpc3Mwk HET   Early adult 5.84×10-05
corneal vascularization Trpc3Mwk HET Early adult 3.21×10-05
limb grasping Trpc3Mwk HET Early adult 1.28×10-05
abnormal response to new environment Trpc3Mwk HET Early adult 5.87×10-05
decreased circulating LDL cholesterol level Trpc3Mwk HET   Early adult 3.31×10-09
abnormal locomotor activation Trpc3Mwk HET Early adult 5.49×10-08
decreased neutrophil cell number Trpc3tm1b(EUCOMM)Wtsi HET Early adult 2.32×10-05
increased lean body mass Trpc3Mwk HET Early adult 8.92×10-06
decreased prepulse inhibition Trpc3Mwk HET   Early adult 7.46×10-06
increased circulating iron level Trpc3Mwk HET   Early adult 4.08×10-05

Download data as:  TSV  XLS

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Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 4 No  (3/590) N/A
Aorta 4 No  (1/590) N/A
Bone 4 No N/A
Brain 4 No  (3/590) N/A
Brainstem 4 No  (2/590) N/A
Brown adipose tissue 4 No N/A
Cartilage tissue 4 No N/A
Cecum 4 No  (12/377) N/A
Cerebellum 4 No  (3/590) N/A
Cerebral cortex 4 No  (2/590) N/A
Chest bone 4 No N/A
Colon 4 No  (12/127) N/A
Cranium 4 No N/A
Diaphragm 4 No N/A
Duodenum 4 No  (2/127) N/A
Epididymis 4 No  (18/134) N/A
Esophagus 4 No  (7/415) N/A
Eye 4 No N/A
Gall bladder 4 No N/A
Gonadal fat pad 4 No N/A
Harderian gland 4 No N/A
Heart 4 No  (1/590) N/A
Hindlimb 4 No N/A
Hippocampus 4 No  (3/590) N/A
Hypothalamus 4 No  (2/590) N/A
Ileum 4 No  (14/127) N/A
Jejunum 4 No  (6/127) N/A
Kidney 4 No  (20/590) N/A
Large intestine 4 No  (10/590) N/A
Liver 4 No N/A
Lower urinary tract 4 No  (1/590) N/A
Lung 4 No  (1/590) N/A
Lymph node 4 No N/A
Main olfactory bulb 4 No N/A
Mammary gland 4 No N/A
Mesenteric adipose tissue 4 No N/A
Mesenteric lymph node 4 No N/A
Midbrain 4 No N/A
Olfactory lobe 4 No  (2/590) N/A
Oral epithelium 4 No N/A
Ovary 4 No  (1/590) N/A
Oviduct 4 No N/A
Pancreas 4 No  (5/590) N/A
Parathyroid gland 4 No N/A
Parotid gland 4 No N/A
Penis 4 No N/A
Peripheral nervous system 4 No  (1/590) N/A
Peyer's patch 4 No N/A
Pituitary gland 4 No  (1/590) N/A
Prostate gland 4 No  (12/590) N/A
Quadriceps 4 No N/A
Sciatic nerve 4 No N/A
Skeletal muscle 4 No N/A
Skin 4 No N/A
Small intestine 4 No  (9/590) N/A
Spinal cord 4 No  (2/590) N/A
Spleen 4 No  (2/590) N/A
Stomach 4 No  (13/590) N/A
Stomach pyloric region 4 No N/A
Striatum 4 No  (3/590) N/A
Sublingual gland 4 No N/A
Submandibular gland 4 No  (2/132) N/A
Testis 4 No  (5/590) N/A
Thalamus 4 No N/A
Thymus 4 No N/A
Thyroid gland 4 No  (16/590) N/A
Tongue 4 No  (5/127) N/A
Trachea 4 No  (2/590) N/A
Trigeminal V nerve 4 No N/A
Urinary bladder 4 No N/A
Uterus 4 No N/A
Vagina 4 No N/A
Vas deferens 4 No  (15/388) N/A
Vascular system 4 No N/A
Vesicular gland 4 No N/A
White adipose tissue 4 No N/A
LacZ Wholemount Images
Unassigned Top Level MA (72)
LacZ Section Images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 7  (6/506) N/A
Ear 7  (1/506) N/A
Embryo 7  (1/507)  Wholemount images
Eye 7  (1/506) N/A
Foot 7  (1/506) N/A
Forearm 7  (1/303) N/A
Forebrain 7  (1/506) N/A
Forelimb 7  (1/506) N/A
Hand 7  (1/506) N/A
Head 7  (5/506) N/A
Heart 7  (1/506) N/A
Hindbrain 7  (6/506) N/A
Hindlimb 7  (1/506) N/A
Liver 7  (1/504) N/A
Lower leg 7  (1/303) N/A
Lung 7  (1/504) N/A
Mandibular process 7  (1/506) N/A
Maxillary process 7  (1/506) N/A
Midbrain 7  (1/506) N/A
Oral cavity 7  (1/504) N/A
Skin 7  (1/506) N/A
Tail 7  (1/506) N/A
Tail somite 7  (1/506) N/A
Upper arm 7  (1/303) N/A
Upper leg 7  (1/303) N/A
embryo or Unassigned (6)
Embryo no expression
EMAPA:16039 embryo

 Associated Images

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Adult LacZ: LacZ Images Wholemount
72 Images
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X-ray: XRay Images Whole Body Dorso Ventral
10 Images
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X-ray: XRay Images Whole Body Lateral Orientation
10 Images
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Eye Morphology: Images Ophthalmoscopy
4 Images
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Embryo LacZ: LacZ images wholemount
6 Images
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Eye Morphology: Images Slit Lamp
1 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Trpc3tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Trpc3tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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