Gene: Trpc6

Name
transient receptor potential cation channel, subfamily C, member 6
MGI ID
MGI:109523
Synonyms
mtrp6 Trrp6
Viability
Homozygous - Viable
Other links
View data by physiological system
Significant
Not Significant
Not tested

Filtered by: all phenotypes

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Allele Center Procedure / Parameter Zygosity Mutants Statistical
Method
P Value Status
Trpc6tm1.1(NCOM)Mfgc RBRC Combined SHIRPA and Dysmorphology / Tail - thickness HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC Combined SHIRPA and Dysmorphology / Forelimb digit - size HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC Clinical Chemistry / Alanine aminotransferase HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.710 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Combined SHIRPA and Dysmorphology / Coat - hair distribution - back HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC Eye Morphology / Bulging eye HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC Combined SHIRPA and Dysmorphology / Forelimb nail - shape HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC Combined SHIRPA and Dysmorphology / Skin texture - whole body HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC Combined SHIRPA and Dysmorphology / Trunk curl HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC Clinical Chemistry / Creatinine HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.583 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Eye Morphology / Iris/Pupil HOM 7f:7m Fisher Exact Test framework 1.00 Success
Trpc6tm1.1(NCOM)Mfgc RBRC X-ray / Number of thoracic vertebrae HOM 5f:5m 1.00 Success
Trpc6tm1.1(NCOM)Mfgc RBRC X-ray / Kyphosis HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC X-ray / Lumbar processes HOM 5f:5m Fisher Exact Test framework 1.00 Success
Trpc6tm1.1(NCOM)Mfgc RBRC X-ray / Radius HOM 5f:5m Fisher Exact Test framework 1.00 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Eye Morphology / Corneal deposits HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC Indirect Calorimetry / Total food intake HOM 7f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.548 Success
Trpc6tm1.1(NCOM)Mfgc RBRC X-ray / Fibula HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC Open Field / Percentage center time HOM 7f:7m Mixed Model framework, generalized least squares, equation withoutWeight 0.283 Success
Trpc6tm1.1(NCOM)Mfgc RBRC X-ray / Shape of vertebrae HOM 5f:5m Fisher Exact Test framework 0.00302 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Body Composition (DEXA lean/fat) / Body length HOM 7f:7m Mixed Model framework, generalized least squares, equation withoutWeight 0.365 Success
Trpc6tm1.1(NCOM)Mfgc RBRC X-ray / Brachydactyly HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC Combined SHIRPA and Dysmorphology / Vibrissae - presence HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Thyroid HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Thyroid HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Thyroid HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Thyroid HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Combined SHIRPA and Dysmorphology / Lower teeth appearance HOM 7f:7m Fisher Exact Test framework 1.00 Success
Trpc6tm1.1(NCOM)Mfgc RBRC X-ray / Scapulae HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC Eye Morphology / Lens Opacity HOM 7f:7m Fisher Exact Test framework 1.00 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Combined SHIRPA and Dysmorphology / Skin texture - back paws HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC Clinical Chemistry / LDL-cholesterol HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0881 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Combined SHIRPA and Dysmorphology / Forelimbs - shape HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC Open Field / Periphery distance travelled HOM 7f:7m Mixed Model framework, generalized least squares, equation withoutWeight 0.00477 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Eye Morphology / Retina (combined) HOM 7f:7m Not processed Success
Trpc6tm1.1(NCOM)Mfgc RBRC Eye Morphology / Corneal mineralization HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC X-ray / Zygomatic bone HOM 5f:5m Fisher Exact Test framework 1.00 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Spleen HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Spleen HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Spleen HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Spleen HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Clinical Chemistry / Calcium HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.399 Success
Trpc6tm1.1(NCOM)Mfgc RBRC X-ray / Shape of ribs HOM 5f:5m Fisher Exact Test framework 0.374 Success
Trpc6tm1.1(NCOM)Mfgc RBRC X-ray / Polysyndactylism HOM 5f:5m Fisher Exact Test framework 1.00 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Combined SHIRPA and Dysmorphology / Contact righting HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC Combined SHIRPA and Dysmorphology / Hindlimb nail - number HOM 7f:7m Fisher Exact Test framework 1.00 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Combined SHIRPA and Dysmorphology / Skin color - ear HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Esophagus HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Esophagus HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Esophagus HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Esophagus HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Grip Strength / Forelimb and hindlimb grip strength normalised against body weight HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.676 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - head HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC Intraperitoneal glucose tolerance test (IPGTT) / Area under glucose response curve HOM 7f:7m Mixed Model framework, generalized least squares, equation withoutWeight 0.108 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Clinical Chemistry / Creatine kinase HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.809 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Combined SHIRPA and Dysmorphology / Coat - color - abdomen HOM 7f:7m Fisher Exact Test framework 1.00 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Eye Morphology / Pupil Dilation HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC Body Composition (DEXA lean/fat) / Fat mass HOM 7f:7m Mixed Model framework, generalized least squares, equation withoutWeight 0.748 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3 HOM 7f:7m Mixed Model framework, generalized least squares, equation withoutWeight 0.802 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Clinical Chemistry / Phosphorus HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0961 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Combined SHIRPA and Dysmorphology / Hindpaw - shape HOM 7f:7m Fisher Exact Test framework 1.00 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Combined SHIRPA and Dysmorphology / Tremor HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC Viability Primary Screen / Outcome HOM 60f:75m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Combined SHIRPA and Dysmorphology / Genitalia - morphology HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Brain HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Brain HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Brain HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Brain HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Lymph node HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Lymph node HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Lymph node HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Lymph node HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Indirect Calorimetry / Total water intake HOM 6f:6m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.317 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Combined SHIRPA and Dysmorphology / Head morphology HOM 7f:7m Fisher Exact Test framework 1.00 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Combined SHIRPA and Dysmorphology / Upper teeth appearance HOM 7f:7m Fisher Exact Test framework 1.00 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Open Field / Center distance travelled HOM 7f:7m Mixed Model framework, generalized least squares, equation withoutWeight 0.388 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Eye Morphology / Corneal vascularization HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC Eye Morphology / Retinal Blood Vessels Pattern HOM 7f:7m Fisher Exact Test framework 0.00100 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Clinical Chemistry / Triglycerides HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.186 Success
Trpc6tm1.1(NCOM)Mfgc RBRC X-ray / Clavicle HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC Combined SHIRPA and Dysmorphology / Activity (body position) HOM 7f:7m Fisher Exact Test framework 1.00 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Liver HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Liver HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Liver HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Liver HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Combined SHIRPA and Dysmorphology / Hindlimb digit - size HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC X-ray / Digit integrity HOM 5f:5m Fisher Exact Test framework 1.00 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Thymus HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Thymus HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Thymus HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Thymus HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Combined SHIRPA and Dysmorphology / Skin texture - snout HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC Clinical Chemistry / Total protein HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.453 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Eye Morphology / Pupil Position HOM 7f:7m Fisher Exact Test framework 0.185 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Body Composition (DEXA lean/fat) / Fat/Body weight HOM 7f:7m Mixed Model framework, generalized least squares, equation withoutWeight 0.976 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Combined SHIRPA and Dysmorphology / Hindlimbs - position HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC X-ray / Number of cervical vertebrae HOM 5f:5m 1.00 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Open Field / Latency to center entry HOM 7f:7m Mixed Model framework, generalized least squares, equation withoutWeight 0.419 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Eye Morphology / Eyelid closure HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC X-ray / Scoliosis HOM 5f:5m Fisher Exact Test framework 1.00 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Combined SHIRPA and Dysmorphology / Forelimbs - size HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC X-ray / Fusion of vertebrae HOM 5f:5m Fisher Exact Test framework 0.227 Success
Trpc6tm1.1(NCOM)Mfgc RBRC X-ray / Tibia HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC Combined SHIRPA and Dysmorphology / Tail - morphology HOM 7f:7m Fisher Exact Test framework 1.00 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Combined SHIRPA and Dysmorphology / Coat - color pattern - abdomen HOM 7f:7m Fisher Exact Test framework 1.00 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Clinical Chemistry / Aspartate aminotransferase HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.925 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Combined SHIRPA and Dysmorphology / Hindlimb nail - length HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC Combined SHIRPA and Dysmorphology / Vocalization HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC Grip Strength / Forelimb and hindlimb grip strength measurement mean HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.602 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Open Field / Whole arena resting time HOM 7f:7m Mixed Model framework, generalized least squares, equation withoutWeight 0.856 Success
Trpc6tm1.1(NCOM)Mfgc RBRC X-ray / Syndactylism HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC Eye Morphology / Vitreous HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC Combined SHIRPA and Dysmorphology / Teeth presence HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC Eye Morphology / Lens HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC Grip Strength / Forelimb grip strength normalised against body weight HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.256 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Combined SHIRPA and Dysmorphology / Head size HOM 7f:7m Fisher Exact Test framework 1.00 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Combined SHIRPA and Dysmorphology / Coat - color pattern - back HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC Eye Morphology / Optic Disc HOM 7f:7m Fisher Exact Test framework 1.00 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Open Field / Center average speed HOM 7f:7m Mixed Model framework, generalized least squares, equation withoutWeight 0.0607 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Eye Morphology / Narrow eye opening HOM 7f:7m Fisher Exact Test framework 1.00 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Heart Weight / Heart weight HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.147 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Combined SHIRPA and Dysmorphology / Forepaw - shape HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC Body Composition (DEXA lean/fat) / Bone Mineral Content (excluding skull) HOM 7f:7m Mixed Model framework, generalized least squares, equation withoutWeight 0.187 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Combined SHIRPA and Dysmorphology / Skin color - snout HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Skin HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Skin HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Skin HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Skin HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - back HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Lung HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Lung HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Lung HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Lung HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Clinical Chemistry / HDL-cholesterol HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.624 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Eye Morphology / Persistence of hyaloid vascular system HOM 7f:7m Fisher Exact Test framework 0.465 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2 HOM 7f:7m Mixed Model framework, generalized least squares, equation withoutWeight 0.156 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S HOM 7f:7m Mixed Model framework, generalized least squares, equation withoutWeight 0.539 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Eye Morphology / Pupil Shape HOM 7f:7m Fisher Exact Test framework 1.00 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Open Field / Periphery average speed HOM 7f:7m Mixed Model framework, generalized least squares, equation withoutWeight 0.0169 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Fertility of Homozygous Knock-out Mice / Gross Findings Male HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC X-ray / Processes on vertebrae HOM 5f:5m Fisher Exact Test framework 0.184 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Eye Morphology / Eye HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC X-ray / Cervical processes HOM 5f:5m Fisher Exact Test framework 0.388 Success
Trpc6tm1.1(NCOM)Mfgc RBRC X-ray / Maxilla/Pre-maxilla HOM 5f:5m Fisher Exact Test framework 1.00 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Clinical Chemistry / Lactate dehydrogenase HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.571 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Pancreas HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Pancreas HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Pancreas HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Pancreas HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Combined SHIRPA and Dysmorphology / Mouth morphology HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC X-ray / Caudal processes HOM 5f:5m Fisher Exact Test framework 1.00 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Combined SHIRPA and Dysmorphology / Head bobbing HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Spinal cord HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Spinal cord HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Spinal cord HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Spinal cord HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Body Composition (DEXA lean/fat) / Lean/Body weight HOM 7f:7m Mixed Model framework, generalized least squares, equation withoutWeight 0.169 Success
Trpc6tm1.1(NCOM)Mfgc RBRC X-ray / Number of ribs right HOM 5f:5m Not processed 1.00 FAILED - No variability in dependent variable 'IMPC_XRY_008_001'.
Trpc6tm1.1(NCOM)Mfgc RBRC Combined SHIRPA and Dysmorphology / Skin texture - ear HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC Open Field / Distance travelled - total HOM 7f:7m Mixed Model framework, generalized least squares, equation withoutWeight 0.00459 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Combined SHIRPA and Dysmorphology / Snout size HOM 7f:7m Fisher Exact Test framework 1.00 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Clinical Chemistry / Alpha-amylase HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.218 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Eye Morphology / Synechia HOM 7f:7m Fisher Exact Test framework 1.00 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Clinical Chemistry / Iron HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.167 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Clinical Chemistry / Total cholesterol HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.978 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Combined SHIRPA and Dysmorphology / Genitalia - size HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC Open Field / Periphery permanence time HOM 7f:7m Mixed Model framework, generalized least squares, equation withoutWeight 0.283 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Clinical Chemistry / Albumin HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.905 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Combined SHIRPA and Dysmorphology / Forelimb nail - length HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC Intraperitoneal glucose tolerance test (IPGTT) / Initial response to glucose challenge HOM 7f:7m Mixed Model framework, generalized least squares, equation withoutWeight 0.983 Success
Trpc6tm1.1(NCOM)Mfgc RBRC X-ray / Transitional vertebrae HOM 5f:5m Fisher Exact Test framework 1.00 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Combined SHIRPA and Dysmorphology / Aggression HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC Open Field / Number of center entries HOM 7f:7m Mixed Model framework, generalized least squares, equation withoutWeight 0.0440 Success
Trpc6tm1.1(NCOM)Mfgc RBRC X-ray / Pelvis HOM 5f:5m Fisher Exact Test framework 0.479 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Adrenal gland HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Adrenal gland HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Adrenal gland HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Adrenal gland HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Grip Strength / Forelimb grip strength measurement mean HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.241 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Combined SHIRPA and Dysmorphology / Hindlimbs - shape HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC Combined SHIRPA and Dysmorphology / Startle response HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Urinary bladder HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Urinary bladder HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Urinary bladder HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Urinary bladder HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC X-ray / Shape of spine HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC Eye Morphology / Eyelid morphology HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC Combined SHIRPA and Dysmorphology / Forelimb digit - shape HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Gall bladder HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Gall bladder HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Gall bladder HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Gall bladder HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Combined SHIRPA and Dysmorphology / Coat - color - back HOM 7f:7m Fisher Exact Test framework 1.00 Success
Trpc6tm1.1(NCOM)Mfgc RBRC X-ray / Femur HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC Eye Morphology / Cornea HOM 7f:7m Fisher Exact Test framework 1.00 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Open Field / Center permanence time HOM 7f:7m Mixed Model framework, generalized least squares, equation withoutWeight 0.283 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Combined SHIRPA and Dysmorphology / Hindpaw - size HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC Body Composition (DEXA lean/fat) / Bone Mineral Density (excluding skull) HOM 7f:7m Mixed Model framework, generalized least squares, equation withoutWeight 0.0101 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Combined SHIRPA and Dysmorphology / Upper lip morphology HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC Combined SHIRPA and Dysmorphology / Locomotor activity HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.895 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Skeletal muscle HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Skeletal muscle HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Skeletal muscle HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Skeletal muscle HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Combined SHIRPA and Dysmorphology / Skin texture - tail HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC Combined SHIRPA and Dysmorphology / Vibrissae - appearance HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC Eye Morphology / Iris Pigmentation HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1 HOM 7f:7m Mixed Model framework, generalized least squares, equation withoutWeight 0.426 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Eye Morphology / Retinal Blood Vessels HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC Eye Morphology / Lacrimation HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC X-ray / Mandibles HOM 5f:5m Fisher Exact Test framework 1.00 Success
Trpc6tm1.1(NCOM)Mfgc RBRC X-ray / Thoracic processes HOM 5f:5m Fisher Exact Test framework 1.00 Success
Trpc6tm1.1(NCOM)Mfgc RBRC X-ray / Humerus HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC Combined SHIRPA and Dysmorphology / Skin color - back paws HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Large intestine HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Large intestine HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Large intestine HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Large intestine HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Combined SHIRPA and Dysmorphology / Limb grasp HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC Combined SHIRPA and Dysmorphology / Skin color - whole body HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC X-ray / Number of digits HOM 5f:5m Not processed 1.00 FAILED - No variability in dependent variable 'IMPC_XRY_028_001'.
Trpc6tm1.1(NCOM)Mfgc RBRC Combined SHIRPA and Dysmorphology / Coat - hair distribution - abdomen HOM 7f:7m Fisher Exact Test framework 1.00 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Clinical Chemistry / Urea (Blood Urea Nitrogen - BUN) HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.358 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Combined SHIRPA and Dysmorphology / Coat - color pattern - head HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC Open Field / Periphery resting time HOM 7f:7m Mixed Model framework, generalized least squares, equation withoutWeight 0.812 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Combined SHIRPA and Dysmorphology / Genitalia - presence HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC X-ray / Number of lumbar vertebrae HOM 5f:5m 1.00 Success
Trpc6tm1.1(NCOM)Mfgc RBRC X-ray / Lordosis HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC Combined SHIRPA and Dysmorphology / Hindlimb nail - shape HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC X-ray / Ulna HOM 5f:5m Fisher Exact Test framework 1.00 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Combined SHIRPA and Dysmorphology / Coat - hair distribution - head HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC X-ray / Sacral processes HOM 5f:5m Fisher Exact Test framework 1.00 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Eye Morphology / Corneal Sclerization HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC Clinical Chemistry / Alkaline phosphatase HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.783 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Combined SHIRPA and Dysmorphology / Hindlimb digit - number HOM 7f:7m Fisher Exact Test framework 1.00 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Stomach HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Stomach HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Stomach HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Stomach HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Combined SHIRPA and Dysmorphology / Tail - length HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC Eye Morphology / Eye Hemorrhage or Blood Presence HOM 7f:7m Fisher Exact Test framework 1.00 Success
Trpc6tm1.1(NCOM)Mfgc RBRC X-ray / Number of caudal vertebrae HOM 5f:5m Not processed 1.00 FAILED - Insufficient data in the dependent variable 'IMPC_XRY_017_001' control subset (Female - 60, Male - 59) to allow the application of RR plus framework.
Trpc6tm1.1(NCOM)Mfgc RBRC Combined SHIRPA and Dysmorphology / Unexpected behaviors HOM 7f:7m Fisher Exact Test framework 1.00 Success
Trpc6tm1.1(NCOM)Mfgc RBRC X-ray / Teeth HOM 5f:5m Fisher Exact Test framework 1.00 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - Global HOM 7f:7m Mixed Model framework, generalized least squares, equation withoutWeight 0.114 Success
Trpc6tm1.1(NCOM)Mfgc RBRC X-ray / Number of ribs left HOM 5f:5m 1.00 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Combined SHIRPA and Dysmorphology / Hindlimbs - size HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC Combined SHIRPA and Dysmorphology / Skin texture - front paws HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC Body Composition (DEXA lean/fat) / Bone Area HOM 7f:7m Mixed Model framework, generalized least squares, equation withoutWeight 0.652 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Eye Morphology / Fusion between cornea and lens HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC Combined SHIRPA and Dysmorphology / Coat - color - head HOM 7f:7m Fisher Exact Test framework 1.00 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Combined SHIRPA and Dysmorphology / Hindlimb digit - shape HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC Intraperitoneal glucose tolerance test (IPGTT) / Fasted blood glucose concentration HOM 7f:7m Mixed Model framework, generalized least squares, equation withoutWeight 0.599 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Combined SHIRPA and Dysmorphology / Forepaw - size HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Heart HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Heart HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Heart HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Heart HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Clinical Chemistry / Total bilirubin HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.117 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Combined SHIRPA and Dysmorphology / Forelimbs - position HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC X-ray / Fusion of ribs HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC Body Composition (DEXA lean/fat) / BMC/Body weight HOM 7f:7m Mixed Model framework, generalized least squares, equation withoutWeight 0.599 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Combined SHIRPA and Dysmorphology / Lower lip morphology HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Trachea HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Trachea HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Trachea HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Trachea HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Combined SHIRPA and Dysmorphology / Skin color - front paws HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - abdomen HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC Open Field / Center resting time HOM 7f:7m Mixed Model framework, generalized least squares, equation withoutWeight 0.0886 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Clinical Chemistry / Glucose HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.137 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Eye Morphology / Retinal Blood Vessels Structure HOM 7f:7m Fisher Exact Test framework 1.00 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Fertility of Homozygous Knock-out Mice / Gross Findings Female HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC X-ray / Joints HOM 5f:5m Fisher Exact Test framework 0.182 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Eye Morphology / Corneal ulcer HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC X-ray / Skull shape HOM 5f:5m Fisher Exact Test framework 1.00 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Combined SHIRPA and Dysmorphology / Forelimb nail - number HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC Combined SHIRPA and Dysmorphology / Gait HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Kidney HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Kidney HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Kidney HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Kidney HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC X-ray / Fusion of processes HOM 5f:5m Fisher Exact Test framework 0.222 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Combined SHIRPA and Dysmorphology / Ears HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Small intestine HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Small intestine HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Small intestine HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Small intestine HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Combined SHIRPA and Dysmorphology / Forelimb digit - number HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC Combined SHIRPA and Dysmorphology / Tail - presence HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Trpc6tm1.1(NCOM)Mfgc RBRC Clinical Chemistry / Uric acid HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.627 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI4 HOM 7f:7m Mixed Model framework, generalized least squares, equation withWeight 0.0176 Success
Trpc6tm1.1(NCOM)Mfgc RBRC X-ray / Tibia length HOM 5f:5m Mixed Model framework, linear mixed-effects model, equation withWeight 0.296 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Body Composition (DEXA lean/fat) / Lean mass HOM 7f:7m Mixed Model framework, generalized least squares, equation withoutWeight 0.821 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Eye Morphology / Pupil Light Response HOM 7f:7m Fisher Exact Test framework 1.00 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Open Field / Whole arena average speed HOM 7f:7m Mixed Model framework, generalized least squares, equation withoutWeight 0.00459 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Clinical Chemistry / Glycosilated hemoglobin A1c (HbA1c) HOM 7f:7m Mixed Model framework, linear mixed-effects model, equation withWeight 0.642 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Eye Morphology / Corneal opacity HOM 7f:7m Fisher Exact Test framework 1.00 Success
Trpc6tm1.1(NCOM)Mfgc RBRC X-ray / Number of pelvic vertebrae HOM 5f:5m 1.00 Success
Trpc6tm1.1(NCOM)Mfgc RBRC X-ray / Shape of ribcage HOM 5f:5m Fisher Exact Test framework 0.437 Success
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Eye with optic nerve HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Eye with optic nerve HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Eye with optic nerve HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Gross Pathology and Tissue Collection / Eye with optic nerve HOM f:m Supplied as data Success
Trpc6tm1.1(NCOM)Mfgc RBRC Combined SHIRPA and Dysmorphology / Skin color - tail HOM 7f:7m Fisher Exact Test framework 1.00 Not tested (No variation) - OK

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 4 Yes  (2/584)  Wholemount images
Aorta 4 No N/A
Bone 4 No N/A
Brain 4 Yes  (6/6)  Wholemount images
Brainstem 4 No N/A
Brown adipose tissue 4 No N/A
Cartilage tissue 4 No N/A
Cecum 4 Yes  (12/383)  Wholemount images
Cerebellum 4 No N/A
Cerebral cortex 4 No  (6/6) N/A
Chest bone 4 Yes  Wholemount images
Colon 4 No  (12/127) N/A
Cranium 4 No N/A
Diaphragm 4 No N/A
Duodenum 4 Yes  (2/127)  Wholemount images
Epididymis 4 Yes  (18/134)  Wholemount images
Esophagus 4 Yes  (7/415)  (6/6)  Wholemount images
Eye 4 No N/A
Gall bladder 4 Yes  Wholemount images
Gonadal fat pad 4 No N/A
Harderian gland 4 Yes  Wholemount images
Heart 4 No N/A
Hindlimb 4 No N/A
Hippocampus 4 No  (6/6) N/A
Hypothalamus 4 No N/A
Ileum 4 Yes  (14/127)  Wholemount images
Jejunum 4 Yes  (6/127)  Wholemount images
Kidney 4 Yes  (18/584)  (6/6)  Wholemount images
Large intestine 4 Yes  (10/584)  Wholemount images
Liver 4 Yes  Wholemount images
Lower urinary tract 4 No N/A
Lung 4 Yes  (6/6)  Wholemount images
Lymph node 4 Yes  Wholemount images
Main olfactory bulb 4 Yes  Wholemount images
Mammary gland 4 Yes  (3/6)  Wholemount images
Mesenteric adipose tissue 4 No N/A
Mesenteric lymph node 4 Yes  Wholemount images
Midbrain 4 No N/A
Olfactory lobe 4 Yes  Wholemount images
Oral epithelium 4 No N/A
Ovary 4 Yes  (1/584)  (3/6)  Wholemount images
Oviduct 4 Yes  (3/6)  Wholemount images
Pancreas 4 Yes  (5/584)  (6/6)  Wholemount images
Parathyroid gland 4 Yes  Wholemount images
Parotid gland 4 Yes  Wholemount images
Penis 4 Yes  (3/6)  Wholemount images
Peripheral nervous system 4 No N/A
Peyer's patch 4 Yes  Wholemount images
Pituitary gland 4 Yes  Wholemount images
Prostate gland 4 Yes  (12/584)  Wholemount images
Quadriceps 4 No N/A
Sciatic nerve 4 No N/A
Skeletal muscle 4 No N/A
Skin 4 Yes  Wholemount images
Small intestine 4 No  (9/584) N/A
Spinal cord 4 No N/A
Spleen 4 Yes  (2/584)  (6/6)  Wholemount images
Stomach 4 Yes  (12/584)  Wholemount images
Stomach pyloric region 4 No N/A
Striatum 4 No N/A
Sublingual gland 4 Yes  Wholemount images
Submandibular gland 4 Yes  (2/132)  Wholemount images
Testis 4 Yes  (2/584)  Wholemount images
Thalamus 4 No N/A
Thymus 4 Yes  Wholemount images
Thyroid gland 4 Yes  (15/584)  Wholemount images
Tongue 4 Yes  (5/127)  (6/6)  Wholemount images
Trachea 4 Yes  Wholemount images
Trigeminal V nerve 4 Yes  (6/6)  Wholemount images
Urinary bladder 4 Yes  Wholemount images
Uterus 4 Yes  (3/6)  Wholemount images
Vagina 4 Yes  (3/6)  Wholemount images
Vas deferens 4 No  (15/388) N/A
Vascular system 4 No  (2/6) N/A
Vesicular gland 4 Yes  (1/6)  Wholemount images
White adipose tissue 4 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 6  (6/485) N/A
Ear 6  (1/485) N/A
Embryo 6  (1/485)  (7/7)  Wholemount images
Eye 6  (1/485) N/A
Foot 6  (1/485)  (7/7) N/A
Forearm 6  (1/282)  (7/7) N/A
Forebrain 6  (1/485) N/A
Forelimb 6  (1/485)  (7/7)  Wholemount images
Hand 6  (1/485)  (7/7) N/A
Head 6  (5/485)  (7/7)  Wholemount images
Heart 6  (1/485)  Wholemount images
Hindbrain 6  (6/485) N/A
Hindlimb 6  (1/485)  (7/7)  Wholemount images
Liver 6  (1/485)  (6/7)  Wholemount images
Lower leg 6  (1/282)  (7/7) N/A
Lung 6  (1/485)  Wholemount images
Mandibular process 6  (1/485)  (6/7) N/A
Maxillary process 6  (1/485)  (6/7) N/A
Midbrain 6  (1/485) N/A
Oral cavity 6  (1/485) N/A
Skin 6  (1/485) N/A
Tail 6  (1/485)  (7/7)  Wholemount images
Tail somite 6  (1/485) N/A
Upper arm 6  (1/282)  (7/7) N/A
Upper leg 6  (1/282)  (7/7) N/A

 Associated Images

Adult LacZ: LacZ Images Wholemount
273 Images
Embryo LacZ: LacZ images wholemount
157 Images
Eye Morphology: Images Ophthalmoscopy
7 Images
X-ray: XRay Images Dorso Ventral
10 Images
X-ray: XRay Images Lateral Orientation
10 Images
Eye Morphology: Images Slit Lamp
1 Images

 Disease Models

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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Trpc6tm1.1(NCOM)Mfgc Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice
Trpc6tm1(NCOM)Mfgc Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells
Trpc6tm403293(L1L2_Bact_P) Targeting vectors

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