Gene: Nfil3

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Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
enlarged spleen Nfil3tm1.1(KOMP)Vlcg HOM Early adult 0.00
small thymus Nfil3tm1.1(KOMP)Vlcg HOM Early adult 0.00
hyperactivity Nfil3tm1.1(KOMP)Vlcg HOM   Early adult 7.76×10-05
abnormal cecum morphology Nfil3tm1.1(KOMP)Vlcg HOM Early adult 0.00
improved glucose tolerance Nfil3tm1.1(KOMP)Vlcg HOM Early adult 8.20×10-08
abnormal pancreas morphology Nfil3tm1.1(KOMP)Vlcg HOM Early adult 0.00
abnormal spleen morphology Nfil3tm1.1(KOMP)Vlcg HOM Early adult 0.00
abnormal thymus morphology Nfil3tm1.1(KOMP)Vlcg HOM Early adult 0.00
microphthalmia Nfil3tm1.1(KOMP)Vlcg HOM Early adult 0.00
abnormal cornea morphology Nfil3tm1.1(KOMP)Vlcg HOM Early adult 1.76×10-06

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (3/590)  (2/2)  Section images
Aorta 2 No  (1/590)  (1/2)  Section images
Blood 2 No N/A
Bone marrow 2 No  (2/2)  Section images
Brain 2 No  (3/590) N/A
Brainstem 2 No  (2/590) N/A
Brown adipose tissue 2 No  (2/2)  Section images
Cartilage tissue 2 No N/A
Cecum 2 No  (12/377)  (1/2)  Section images
Cerebellum 2 No  (3/590)  (2/2)  Section images
Cerebral cortex 2 No  (2/590) N/A
Chest bone 2 No N/A
Colon 2 No  (12/127)  (2/2)  Section images
Diaphragm 2 No  (2/2)  Section images
Duodenum 2 No  (2/127) N/A
Epididymis 2 No  (18/134)  (1/2)  Section images
Esophagus 2 No  (7/415)  (2/2)  Section images
Eye 2 No  (2/2)  Section images
Gall bladder 2 No N/A
Gonadal fat pad 2 No  (2/2)  Section images
Harderian gland 2 No  (2/2)  Section images
Heart 2 No  (1/590) N/A
Hindlimb 2 No N/A
Hippocampus 2 No  (3/590) N/A
Hypothalamus 2 No  (2/590) N/A
Ileum 2 No  (14/127) N/A
Jejunum 2 No  (6/127) N/A
Kidney 2 No  (20/590)  (2/2)  Section images
Large intestine 2 No  (10/590) N/A
Liver 2 No  (2/2)  Section images
Lower urinary tract 2 No  (1/590) N/A
Lung 2 No  (1/590)  (2/2)  Section images
Lymph node 2 No N/A
Mammary gland 2 No  (1/2)  Section images
Mesenteric adipose tissue 2 No  (2/2)  Section images
Mesenteric lymph node 2 No  (1/2)  Section images
Midbrain 2 No  (2/2)  Section images
Olfactory lobe 2 No  (2/590)  (2/2)  Section images
Ovary 2 No  (1/590)  (1/2)  Section images
Oviduct 2 No  (1/2)  Section images
Pancreas 2 No  (5/590)  (2/2)  Section images
Parathyroid gland 2 No N/A
Parotid gland 2 No  (2/2)  Section images
Penis 2 No  (1/2)  Section images
Peripheral nervous system 2 No  (1/590) N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/590)  (2/2)  Section images
Prostate gland 2 No  (12/590)  (1/2)  Section images
Quadriceps 2 No  (2/2)  Section images
Sciatic nerve 2 No N/A
Skeletal muscle 2 No N/A
Skin 2 No  (2/2)  Section images
Small intestine 2 No  (9/590) N/A
Spinal cord 2 No  (2/590)  (2/2)  Section images
Spleen 2 No  (2/590)  (2/2)  Section images
Stomach 2 No  (13/590)  (2/2)  Section images
Stomach pyloric region 2 No N/A
Striatum 2 No  (3/590) N/A
Sublingual gland 2 No  (2/2)  Section images
Submandibular gland 2 No  (2/132)  (2/2)  Section images
Testis 2 No  (5/590)  (1/2)  Section images
Thymus 2 No  (1/2)  Section images
Thyroid gland 2 No  (16/590)  (1/2)  Section images
Tongue 2 No  (5/127)  (2/2)  Section images
Trachea 2 No  (2/590)  (2/2)  Section images
Trigeminal V nerve 2 No  (2/2)  Section images
Urinary bladder 2 No  (2/2)  Section images
Uterus 2 No  (1/2)  Section images
Vagina 2 No  (1/2)  Section images
Vas deferens 2 No  (15/388)  (1/2)  Section images
Vascular system 2 No N/A
Vesicular gland 2 No  (1/2)  Section images
White adipose tissue 2 No N/A
No Embryo expression data was found for this gene.

 Associated Images

Adult LacZ: LacZ Images Section
147 Images
X-ray: XRay Images Whole Body Dorso Ventral
10 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Histopathology

Phenotype Allele Zygosity Sex Life Stage
Eye with optic nerve - cell and tissue damage Nfil3tm1.1(KOMP)Vlcg HOM Early adult
Eye with optic nerve - inflammation Nfil3tm1.1(KOMP)Vlcg HOM Early adult

 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Nfil3tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice, Tissue
Nfil3tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells
Nfil3tm231068(L1L2_Bact_P) Targeting vectors

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