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Genes Phenotypes Help, News, Blog

Gene: Abca4

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Name
ATP-binding cassette, sub-family A (ABC1), member 4
MGI ID
MGI:109424
Synonyms
RmP Rim protein Abc10 D430003I15Rik
Viability
Data available
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (4) Measurements chart (278) All data table (810)
Expression & images (45) Disease models (0) Histopathology (0) Order (2)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
enlarged caudal vertebrae Abca4tm1a(EUCOMM)Wtsi HOM   Early adult 5.79×10-06
increased mean corpuscular hemoglobin Abca4tm1a(EUCOMM)Wtsi HET Early adult 1.95×10-09
decreased circulating amylase level Abca4tm1a(EUCOMM)Wtsi HET Early adult 5.74×10-06
vertebral fusion Abca4tm1a(EUCOMM)Wtsi HOM Early adult 1.31×10-05

Download data as:  TSV  XLS

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Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (3/590) N/A
Aorta 2 No  (1/590) N/A
Blood vessel 2 No N/A
Bone 2 No N/A
Brain 2 No  (3/590) N/A
Brainstem 2 No  (2/590) N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No  (3/590) N/A
Cerebral cortex 2 No  (2/590) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No  (1/590) N/A
Hippocampus 2 No  (3/590) N/A
Hypothalamus 2 No  (2/590) N/A
Kidney 2 No  (20/590) N/A
Large intestine 2 No  (10/590) N/A
Liver 2 No N/A
Lower urinary tract 2 No  (1/590) N/A
Lung 2 No  (1/590) N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Esophagus 2 No N/A
Olfactory lobe 2 No  (2/590) N/A
Ovary 2 No  (1/590) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/590) N/A
Parathyroid gland 2 No N/A
Peripheral nervous system 2 No  (1/590) N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/590) N/A
Prostate gland 2 No  (12/590) N/A
Skeletal muscle tissue 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/590) N/A
Spinal cord 2 No  (2/590) N/A
Spleen 2 No  (2/590) N/A
Stomach 2 No  (13/590) N/A
Striatum 2 No  (3/590) N/A
Testis 2 No  (5/590)  (1/2) N/A
Thymus 2 No N/A
Thyroid gland 2 No  (16/590) N/A
Trachea 2 No  (2/590) N/A
Uterus 2 No N/A
White adipose tissue 2 No N/A
LacZ Wholemount Images
LacZ Section Images
LacZ Section Images
Abca4tm1a(EUCOMM)Wtsi
ovary, HET, Female, WTSI
Abca4tm1a(EUCOMM)Wtsi
testis, HET, Male, WTSI
Abca4tm1a(EUCOMM)Wtsi
ovary, HET, Female, WTSI
Abca4tm1a(EUCOMM)Wtsi
testis, HET, Male, WTSI
Abca4tm1a(EUCOMM)Wtsi
ovary, HET, Female, WTSI
Abca4tm1a(EUCOMM)Wtsi
testis, HET, Male, WTSI
No Embryo expression data was found for this gene.

 Associated Images

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X-ray: XRay Images Skull Dorso Ventral Orientation
14 Images
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X-ray: XRay Images Whole Body Dorso Ventral
14 Images
X-ray: XRay Images Forepaw
13 Images
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X-ray: XRay Images Skull Lateral Orientation
13 Images
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X-ray: XRay Images Whole Body Lateral Orientation
14 Images
Legacy Phenotype Associated Images
Abca4tm1a(EUCOMM)Wtsi
forearm, HET, Female, WTSI
Abca4tm1a(EUCOMM)Wtsi
body, HET, Male, WTSI
Abca4tm1a(EUCOMM)Wtsi
body, HET, Male, WTSI
Abca4tm1a(EUCOMM)Wtsi
head, HET, Male, WTSI
Abca4tm1a(EUCOMM)Wtsi
forearm, HET, Male, WTSI

View all 152 images

Abca4tm1a(EUCOMM)Wtsi
back skin, HOM, Female, WTSI
Abca4tm1a(EUCOMM)Wtsi
back skin, HET, Female, WTSI
Abca4tm1a(EUCOMM)Wtsi
back skin, HET, Female, WTSI
Abca4tm1a(EUCOMM)Wtsi
back skin, HET, Female, WTSI
Abca4tm1a(EUCOMM)Wtsi
eyelids fail to open, right eye, HOM, Female, WTSI
Abca4tm1a(EUCOMM)Wtsi
persistence of hyaloid vascular system, HOM, Female, WTSI
Abca4tm1a(EUCOMM)Wtsi
corneal opacity, HOM, Female, WTSI
Abca4tm1a(EUCOMM)Wtsi
abnormal epidermal pigmentation, HOM, Female, WTSI
Abca4tm1a(EUCOMM)Wtsi
abnormal epidermal pigmentation, HOM, Female, WTSI

 Disease Models

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 Histopathology

 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Abca4tm1(NCOM)Mfgc Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells
Abca4tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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