Hmox2 | heme oxygenase 2

GeneMGI:109373Synonyms: HO-2, HO2

Physiological systems

17 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Immune system Growth/size/body region Hematopoietic system Behavior/neurological Cardiovascular system

12 No significant impact

7 Not tested

Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
42Embryo tissues

Phenotypes

enlarged heart1 supporting datasetHmox2tm1b(EUCOMM)HmguhomozygoteEarly adultN/A * 
abnormal gait1 supporting datasetHmox2tm1b(EUCOMM)HmguhomozygoteEarly adult7.82x10-16 
increased red blood cell distribution width1 supporting datasetHmox2tm1b(EUCOMM)HmguhomozygoteEarly adult3.21x10-5 
decreased monocyte cell number1 supporting datasetHmox2tm1b(EUCOMM)HmguhomozygoteEarly adult9.77x10-5 
increased spleen weight1 supporting datasetHmox2tm1b(EUCOMM)HmguhomozygoteEarly adult4.54x10-53 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Hmox2tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Hmox2tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Hmox2tm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Hmox2tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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