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Gene: Krt86 MGI:109362

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Gene Summary

Name:
keratin 86
Synonyms:
Khb4,  Krt2-11,  Krt2-10,  MHb4

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IMPC Data Collections

IMPC Phenotype Summary

Significant
Not Significant
Not tested

View all our phenotype data below

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

Phenotype System Allele Zyg Sex Life Stage P Value
thick skin Krt86em1(IMPC)Tcp HOM Early adult 0.00
decreased exploration in new environment Krt86em1(IMPC)Tcp HOM   Early adult 5.15×10-05

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Eye Morphology

Images Ophthalmoscopy

107 Images

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Eye Morphology

Images Slit Lamp

96 Images

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X-ray

XRay Images Whole Body Lateral Orientation

10 Images

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X-ray

XRay Images Whole Body Dorso Ventral

10 Images

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X-ray

XRay Images Skull Dorso Ventral Orientation

10 Images

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Gross Pathology and Tissue Collection

Images

8 Images

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X-ray

XRay Images Skull Lateral Orientation

10 Images

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Human diseases caused by Krt86 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

The table below shows human diseases associated to Krt86 by orthology or direct annotation.

Disease Similarity of
phenotypes		 Matching phenotypes Source
Monilethrix
Cognitive impairment ORPHA:573
Monilethrix
OMIM:158000

The table below shows human diseases predicted to be associated to Krt86 by phenotypic similarity.

Disease Similarity of
phenotypes		 Matching phenotypes Source
Monilethrix
Cognitive impairment ORPHA:573
Monilethrix
OMIM:158000

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Krt86

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Krt86.

No publications found that use IMPC mice or data for Krt86.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

MGI Allele Allele Type Produced
Krt86em1(IMPC)Tcp Exon Deletion Mice
Krt86tm94598(L1L2_Bact_P) KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors

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