Gene: Eif2d

Name
eukaryotic translation initiation factor 2D
MGI ID
MGI:109342
Synonyms
Lgtn D1Ertd5e
Viability
Homozygous - Viable
Other links
Significant phenotypes (0) All measurements (29) Expression & images (0) Disease models (0) Order (1)
View data by physiological system
Significant
Not Significant
Not tested

Filtered by: all phenotypes

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Allele Center Procedure / Parameter Zygosity Mutants Statistical
Method
P Value Status
Eif2dem1(IMPC)Mbp UC Davis Eye Morphology / Cornea HOM 11f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Eif2dem1(IMPC)Mbp UC Davis Eye Morphology / Retina (combined) HOM 11f:8m Not processed Success
Eif2dem1(IMPC)Mbp UC Davis Auditory Brain Stem Response / 12kHz-evoked ABR Threshold HOM 2f:2m 0.130 Success
Eif2dem1(IMPC)Mbp UC Davis Electrocardiogram (ECG) / RR HOM 11f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.695 Success
Eif2dem1(IMPC)Mbp UC Davis Eye Morphology / Lens HOM 11f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Eif2dem1(IMPC)Mbp UC Davis Eye Morphology / Optic Disc HOM 11f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Eif2dem1(IMPC)Mbp UC Davis Eye Morphology / Retinal Blood Vessels Structure HOM 11f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Eif2dem1(IMPC)Mbp UC Davis Fertility of Homozygous Knock-out Mice / Gross Findings Female HOM f:m Supplied as data Success
Eif2dem1(IMPC)Mbp UC Davis Electrocardiogram (ECG) / PR HOM 11f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.587 Success
Eif2dem1(IMPC)Mbp UC Davis Auditory Brain Stem Response / Click-evoked ABR threshold HOM 2f:2m 1.00 Success
Eif2dem1(IMPC)Mbp UC Davis Auditory Brain Stem Response / 24kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Eif2dem1(IMPC)Mbp UC Davis Intraperitoneal glucose tolerance test (IPGTT) / Area under glucose response curve HOM 11f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.961 Success
Eif2dem1(IMPC)Mbp UC Davis Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1 HOM 11f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.299 Success
Eif2dem1(IMPC)Mbp UC Davis Eye Morphology / Retinal Blood Vessels HOM 11f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Eif2dem1(IMPC)Mbp UC Davis Electrocardiogram (ECG) / QRS HOM 11f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.529 Success
Eif2dem1(IMPC)Mbp UC Davis Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3 HOM 11f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.0609 Success
Eif2dem1(IMPC)Mbp UC Davis Intraperitoneal glucose tolerance test (IPGTT) / Initial response to glucose challenge HOM 11f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.605 Success
Eif2dem1(IMPC)Mbp UC Davis Electrocardiogram (ECG) / HR HOM 11f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.662 Success
Eif2dem1(IMPC)Mbp UC Davis Auditory Brain Stem Response / 30kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Eif2dem1(IMPC)Mbp UC Davis Auditory Brain Stem Response / 6kHz-evoked ABR Threshold HOM 2f:2m 0.130 Success
Eif2dem1(IMPC)Mbp UC Davis Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2 HOM 11f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.207 Success
Eif2dem1(IMPC)Mbp UC Davis Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S HOM 11f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.847 Success
Eif2dem1(IMPC)Mbp UC Davis Viability Primary Screen / Outcome HOM 52f:49m Supplied as data Success
Eif2dem1(IMPC)Mbp UC Davis Fertility of Homozygous Knock-out Mice / Gross Findings Male HOM f:m Supplied as data Success
Eif2dem1(IMPC)Mbp UC Davis Intraperitoneal glucose tolerance test (IPGTT) / Fasted blood glucose concentration HOM 11f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.261 Success
Eif2dem1(IMPC)Mbp UC Davis Eye Morphology / Corneal opacity HOM 11f:8m Fisher Exact Test framework 0.401 Success
Eif2dem1(IMPC)Mbp UC Davis Eye Morphology / Lens Opacity HOM 11f:8m Fisher Exact Test framework 1.00 Success
Eif2dem1(IMPC)Mbp UC Davis Electrocardiogram (ECG) / ST HOM 11f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.518 Success
Eif2dem1(IMPC)Mbp UC Davis Auditory Brain Stem Response / 18kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success

 Expression

Expression data not available

 Associated Images

Phenotype associated images not available

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Eif2dem1(IMPC)Mbp Exon Deletion Mice, Tissue

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