banner
Genes Phenotypes Help, News, Blog

Gene: Pitx2

Log in to follow
Name
paired-like homeodomain transcription factor 2
MGI ID
MGI:109340
Synonyms
Otlx2 Brx1b Brx1a Brx1 solurshin Ptx2 Munc30 Pitx2c Pitx2b Pitx2a Rieg
Viability
Data available
Embryo viewer
3D Imaging
Other links
MGI   Ensembl  
Significant phenotypes (10) Measurements chart (216) All data table (442)
Expression & images (46) Disease models (0) Order (2)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
increased grip strength Pitx2tm1b(EUCOMM)Wtsi HET Early adult 5.97×10-08
abnormal tooth morphology Pitx2tm1b(EUCOMM)Wtsi HET Early adult 1.07×10-08
enlarged heart Pitx2tm1b(EUCOMM)Wtsi HET Early adult 0.00
preweaning lethality, complete penetrance Pitx2tm1b(EUCOMM)Wtsi HOM   Early adult 0.00
small testis Pitx2tm1b(EUCOMM)Wtsi HET Early adult 0.00
corneal opacity Pitx2tm1b(EUCOMM)Wtsi HET Early adult 1.53×10-12
irregularly shaped pupil Pitx2tm1b(EUCOMM)Wtsi HET Early adult 7.64×10-06
prenatal lethality Pitx2tm1b(EUCOMM)Wtsi HOM   E18.5 0.00
abnormal optic disk morphology Pitx2tm1b(EUCOMM)Wtsi HET Early adult 9.47×10-16
increased exploration in new environment Pitx2tm1b(EUCOMM)Wtsi HET Early adult 7.65×10-05

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (4/583) N/A
Aorta 2 No  (1/583) N/A
Bone 2 No N/A
Brain 2 No  (4/583)  (2/2)  Wholemount images
Brainstem 2 No  (2/583) N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (1/583) N/A
Cerebellum 2 No  (3/583) N/A
Cerebral cortex 2 No  (2/583) N/A
Esophagus 2 No  (7/407)  (2/2)  Wholemount images
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No  (2/583)  (2/2)  Wholemount images
Hippocampus 2 No  (3/583) N/A
Hypothalamus 2 No  (2/583)  (2/2)  Wholemount images
Kidney 2 No  (21/583) N/A
Large intestine 2 No  (10/583) N/A
Liver 2 No N/A
Lower urinary tract 2 No  (1/583)  (2/2)  Wholemount images
Lung 2 No  (2/583) N/A
Lymph node 2 No  (1/583) N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No  (2/583) N/A
Oral epithelium 2 No  (2/2)  Wholemount images
Ovary 2 No  (1/583) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/583) N/A
Parathyroid gland 2 No  (1/563) N/A
Peripheral nervous system 2 No  (2/583) N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/583)  (2/2)  Wholemount images
Prostate gland 2 No  (12/583) N/A
Skeletal muscle 2 No N/A
Skin 2 No  (1/583) N/A
Small intestine 2 No  (9/583) N/A
Spinal cord 2 No  (3/583) N/A
Spleen 2 No  (3/583) N/A
Stomach 2 No  (13/583)  (2/2)  Wholemount images
Striatum 2 No  (3/583) N/A
Testis 2 No  (6/583)  (1/2)  Wholemount images
Thymus 2 No  (1/583) N/A
Thyroid gland 2 No  (17/583) N/A
Trachea 2 No  (3/583) N/A
Uterus 2 No N/A
Vascular system 2 No N/A
White adipose tissue 2 No N/A
LacZ Wholemount Images
cardiovascular system (1)
Heart expression
MA:0000072
digestive system (2)
Oral epithelium expression
MA:0000344
nervous system (4)
Brain expression
MA:0000168
postnatal mouse (9)
Brain expression
MA:0000168
reproductive system (1)
Testis expression
MA:0000411
respiratory system (1)
Oral epithelium expression
MA:0000344
trunk (3)
Heart expression
MA:0000072
urinary system (1)
Lower Urinary Tract expression
MA:0002636
LacZ Section Images
No Embryo expression data was found for this gene.

 Associated Images

thumbnail
X-ray: XRay Images Whole Body Lateral Orientation
10 Images
thumbnail
Echo: M-Mode Images
28 Images
thumbnail
X-ray: XRay Images Whole Body Dorso Ventral
10 Images
thumbnail
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
thumbnail
Adult LacZ: LacZ Images Wholemount
9 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
4 Images

 Disease Models

Please visit the desktop version to see this section

 Order Mouse and ES Cells

This service may be affected by the Covid-19 pandemic. See how

MGI Allele Allele Type Produced
Pitx2tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Pitx2tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells