Gene: Etv6

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Name
ets variant 6
MGI ID
MGI:109336
Synonyms
Tel translocation-ets-leukemia
Viability
Embryo viewer
N/A
Other links
Expression & images (0) Disease models (0) Order (2)
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal liver morphology Etv6em1(IMPC)Rbrc HET Early adult 0.00
abnormal heart morphology Etv6em1(IMPC)Rbrc HET Early adult 0.00
preweaning lethality, complete penetrance Etv6em1(IMPC)Rbrc HOM   Early adult 0.00
decreased circulating cholesterol level Etv6em1(IMPC)Rbrc HET Early adult 1.69×10-05
small liver Etv6em1(IMPC)Rbrc HET Early adult 0.00
decreased circulating calcium level Etv6em1(IMPC)Rbrc HET Early adult 8.92×10-05
enlarged heart Etv6em1(IMPC)Rbrc HET Early adult 0.00
decreased circulating total protein level Etv6em1(IMPC)Rbrc HET Early adult 3.07×10-05
enlarged heart Etv6em1(IMPC)Rbrc HET Late adult 0.00
small liver Etv6em1(IMPC)Rbrc HET Late adult 0.00
abnormal heart shape Etv6em1(IMPC)Rbrc HET Late adult 0.00
increased blood uric acid level Etv6em1(IMPC)Rbrc HET Early adult 2.43×10-05
abnormal heart morphology Etv6em1(IMPC)Rbrc HET Late adult 0.00
decreased circulating serum albumin level Etv6em1(IMPC)Rbrc HET Early adult 7.77×10-06
abnormal liver morphology Etv6em1(IMPC)Rbrc HET Late adult 0.00
increased kidney weight Etv6em1(IMPC)Rbrc HET Late adult 3.82×10-06
enlarged heart atrium Etv6em1(IMPC)Rbrc HET Late adult 0.00
decreased circulating HDL cholesterol level Etv6em1(IMPC)Rbrc HET Early adult 4.20×10-07

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 Expression

Expression data not available

 Associated Images

Gross Pathology and Tissue Collection
39 Images
Gross Pathology and Tissue Collection
13 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images
X-ray: XRay Images Whole Body Dorso Ventral
10 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Etv6em1(IMPC)Rbrc Indel causing a Frameshift Mutation Mice
Etv6tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

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