Phenotype System Allele Zyg Sex Life Stage P Value
abnormal head shape Nxnem1(IMPC)Bay HOM E18.5 0.00
decreased spleen weight Nxntm1b(EUCOMM)Wtsi HET Early adult 2.77×10-05
unresponsive to tactile stimuli Nxnem1(IMPC)Bay HOM E18.5 0.00
abnormal mammary gland morphology Nxntm1b(EUCOMM)Wtsi HET Early adult 0.00
abnormal facial morphology Nxnem1(IMPC)J HOM E18.5 0.00
irregularly shaped pupil Nxntm1a(EUCOMM)Wtsi HET Early adult 1.12×10-05
decreased mean platelet volume Nxntm1b(EUCOMM)Wtsi HET Early adult 7.38×10-05
abnormal retinal blood vessel morphology Nxnem1(IMPC)Bay HET Early adult 4.82×10-05
increased circulating HDL cholesterol level Nxntm1b(EUCOMM)Wtsi HET Early adult 2.48×10-07
abnormal digit morphology Nxntm1b(EUCOMM)Wtsi HET Early adult 7.98×10-07
abnormal craniofacial morphology Nxntm1b(EUCOMM)Wtsi HOM E12.5 0.00
facial cleft Nxntm1b(EUCOMM)Wtsi HOM E18.5 0.00
abnormal cranium morphology Nxntm1b(EUCOMM)Wtsi HET Early adult 2.41×10-05
decreased lean body mass Nxntm1b(EUCOMM)Wtsi HET Early adult 6.95×10-07
decreased circulating triglyceride level Nxntm1b(EUCOMM)Wtsi HET   Early adult 2.23×10-06
abnormal snout morphology Nxntm1b(EUCOMM)Wtsi HET Early adult 3.54×10-06
decreased mean corpuscular hemoglobin concentration Nxntm1b(EUCOMM)Wtsi HET Early adult 7.89×10-06
abnormal facial morphology Nxnem1(IMPC)Bay HOM E18.5 0.00
unresponsive to tactile stimuli Nxntm1b(EUCOMM)Wtsi HOM E18.5 0.00
abnormal facial morphology Nxntm1b(EUCOMM)Wtsi HOM E18.5 0.00
decreased red blood cell distribution width Nxntm1b(EUCOMM)Wtsi HET Early adult 1.30×10-07
increased grip strength Nxntm1a(EUCOMM)Wtsi HET Early adult 2.57×10-05
abnormal head size Nxntm1b(EUCOMM)Wtsi HOM E18.5 0.00
hypoactivity Nxntm1b(EUCOMM)Wtsi HET Early adult 1.49×10-06
unresponsive to tactile stimuli Nxnem1(IMPC)Bay HET E18.5 0.00
preweaning lethality, incomplete penetrance Nxntm1a(EUCOMM)Wtsi HOM   Early adult 0.00
decreased total body fat amount Nxntm1b(EUCOMM)Wtsi HET Early adult 4.92×10-05
abnormal embryo size Nxnem1(IMPC)J HOM E18.5 0.00
short tibia Nxntm1b(EUCOMM)Wtsi HET   Early adult 8.09×10-11
preweaning lethality, complete penetrance Nxnem1(IMPC)Bay HOM   Early adult 0.00
no spontaneous movement Nxntm1b(EUCOMM)Wtsi HOM E18.5 0.00
abnormal head shape Nxntm1b(EUCOMM)Wtsi HOM E18.5 0.00
small adrenal glands Nxntm1b(EUCOMM)Wtsi HET Early adult 0.00
abnormal retinal blood vessel morphology Nxntm1a(EUCOMM)Wtsi HET Early adult 3.73×10-05
cleft palate Nxntm1b(EUCOMM)Wtsi HOM E15.5 0.00
abnormal head size Nxnem1(IMPC)Bay HOM E18.5 0.00
abnormal embryo size Nxntm1b(EUCOMM)Wtsi HOM E15.5 0.00
abnormal embryo size Nxnem1(IMPC)Bay HOM E18.5 0.00
abnormal craniofacial morphology Nxntm1b(EUCOMM)Wtsi HOM E15.5 0.00
decreased mean corpuscular hemoglobin Nxntm1b(EUCOMM)Wtsi HET Early adult 7.57×10-06
preweaning lethality, complete penetrance Nxnem1(IMPC)J HOM   Early adult 0.00
abnormal eyelid morphology Nxntm1b(EUCOMM)Wtsi HET Early adult 1.78×10-05
cleft palate Nxnem1(IMPC)J HOM E18.5 0.00
anophthalmia Nxntm1a(EUCOMM)Wtsi HET Early adult 0.00
unresponsive to tactile stimuli Nxntm1b(EUCOMM)Wtsi HET E18.5 0.00
cleft palate Nxntm1b(EUCOMM)Wtsi HOM E18.5 0.00
abnormal embryo size Nxntm1b(EUCOMM)Wtsi HOM E18.5 0.00
decreased mean corpuscular volume Nxntm1b(EUCOMM)Wtsi HET Early adult 5.42×10-06
preweaning lethality, complete penetrance Nxntm1b(EUCOMM)Wtsi HOM   Early adult 0.00
facial cleft Nxnem1(IMPC)J HOM E18.5 0.00
decreased cardiac muscle contractility Nxntm1a(EUCOMM)Wtsi HET Early adult 2.46×10-07
facial cleft Nxnem1(IMPC)Bay HOM E18.5 0.00
abnormal optic disk morphology Nxntm1b(EUCOMM)Wtsi HET   Early adult 4.45×10-06

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 17 No  (4/583)  (14/17)  Wholemount images  Section images
Aorta 17 No  (1/583)  (14/17)  Wholemount images  Section images
Blood 4 No N/A
Blood vessel 2 No  (2/2) N/A
Bone 14 No  (4/14)  Wholemount images  Section images
Bone marrow 4 No N/A
Brain 17 No  (4/583)  (17/17)  Wholemount images  Section images
Brainstem 17 No  (2/583)  (11/17)  Wholemount images  Section images
Brown adipose tissue 15 No  (2/15)  Wholemount images  Section images
Cartilage tissue 17 No  (1/583)  (11/17)  Wholemount images  Section images
Cecum 10 No  (12/371)  (8/10)  Wholemount images  Section images
Cerebellum 17 No  (3/583)  (10/17)  Wholemount images  Section images
Cerebral cortex 17 No  (2/583)  (9/17)  Wholemount images  Section images
Chest bone 8 No  (6/8)  Wholemount images  Section images
Colon 8 No  (12/127)  (6/8)  Section images
Cranium 8 No  (2/8)  Section images
Diaphragm 8 No  (6/8)  Wholemount images  Section images
Duodenum 6 No  (2/127)  (6/6)  Wholemount images  Section images
Epididymis 9 No  (18/132)  (1/9)  Wholemount images  Section images
Esophagus 15 No  (7/407)  (13/15)  Wholemount images  Section images
Eye 17 No  (13/17)  Wholemount images  Section images
Gall bladder 14 No  (12/14)  Wholemount images  Section images
Gonadal fat pad 6 No N/A
Harderian gland 8 No  (5/8)  Wholemount images  Section images
Heart 17 No  (2/583)  (7/17)  Wholemount images  Section images
Hindlimb 8 No  (6/8)  Section images
Hippocampus 17 No  (3/583)  (9/17)  Wholemount images  Section images
Hypothalamus 17 No  (2/583)  (9/17)  Wholemount images  Section images
Ileum 6 No  (14/127)  (6/6)  Wholemount images  Section images
Jejunum 6 No  (6/127)  (6/6)  Wholemount images  Section images
Kidney 17 No  (21/583)  (17/17)  Wholemount images  Section images
Large intestine 17 No  (10/583)  (15/17)  Wholemount images  Section images
Liver 17 No  (1/17)  Wholemount images  Section images
Lower urinary tract 17 No  (1/583)  (13/17)  Wholemount images  Section images
Lung 17 No  (2/583)  (16/17)  Wholemount images  Section images
Lymph node 17 No  (1/583)  (5/17)  Wholemount images  Section images
Main olfactory bulb 8 No  (4/8)  Wholemount images
Mammary gland 17 No  (7/17)  Wholemount images  Section images
Mesenteric adipose tissue 6 No  (4/6)  Wholemount images
Mesenteric lymph node 10 No  (2/10)  Wholemount images
Midbrain 7 No  (5/7)  Section images
Esophagus 2 No  (2/2) N/A
Olfactory lobe 17 No  (2/583)  (11/17)  Wholemount images  Section images
Oral epithelium 12 No  (6/12)  Wholemount images  Section images
Ovary 17 No  (1/583)  (7/17)  Wholemount images  Section images
Oviduct 17 No  (7/17)  Wholemount images  Section images
Pancreas 17 No  (5/583)  (3/17)  Wholemount images  Section images
Parathyroid gland 14 No  (1/563)  (4/14)  Wholemount images  Section images
Parotid gland 8 No  (4/8)  Wholemount images
Penis 8 No  (3/8)  Wholemount images  Section images
Peripheral nervous system 17 No  (2/583)  (14/17)  Wholemount images  Section images
Peyer's patch 2 No  (1/176)  (2/2) N/A
Peyer's patch 15 No  (4/15)  Wholemount images  Section images
Pituitary gland 17 No  (1/583)  (13/17)  Wholemount images  Section images
Prostate gland 17 No  (12/583)  (7/17)  Wholemount images  Section images
Quadriceps 6 No  (6/6)  Wholemount images  Section images
Sciatic nerve 8 No  (4/8)  Wholemount images
Skeletal muscle 15 No  (13/15)  Wholemount images  Section images
Skeletal muscle tissue 2 No  (2/2) N/A
Skin 17 No  (1/583)  (15/17)  Wholemount images  Section images
Small intestine 17 No  (9/583)  (15/17)  Wholemount images  Section images
Spinal cord 17 No  (3/583)  (13/17)  Wholemount images  Section images
Spleen 17 No  (3/583)  (7/17)  Wholemount images  Section images
Stomach 17 No  (13/583)  (16/17)  Wholemount images  Section images
Stomach pyloric region 8 No N/A
Striatum 17 No  (3/583)  (9/17)  Wholemount images  Section images
Sublingual gland 8 No  (4/8)  Wholemount images
Submandibular gland 9 No  (2/130)  (5/9)  Wholemount images  Section images
Testis 17 No  (6/583)  (9/17)  Wholemount images  Section images
Thalamus 7 No  (1/7)  Section images
Thymus 17 No  (1/583)  (7/17)  Wholemount images  Section images
Thyroid gland 17 No  (17/583)  (4/17)  Wholemount images  Section images
Tongue 8 No  (5/127)  (6/8)  Wholemount images  Section images
Trachea 17 No  (3/583)  (15/17)  Wholemount images  Section images
Trigeminal V nerve 10 No  (6/10)  Wholemount images
Urinary bladder 11 No  (9/11)  Wholemount images  Section images
Uterus 17 No  (8/17)  Wholemount images  Section images
Vagina 8 No  (3/8)  Wholemount images  Section images
Vas deferens 10 No  (15/382)  Wholemount images
Vascular system 15 No  (13/15)  Wholemount images  Section images
Vesicular gland 9 No  (2/9)  Wholemount images
White adipose tissue 17 No  (1/17)  Section images
LacZ Section Images

View all 23 images

View all 16 images

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
6  (1/60)  (9/9) N/A
8  (1/64)  (11/11) N/A
24  (6/505)  (27/31) N/A
10  (1/73)  (11/13) N/A
6  (1/64)  (4/6) N/A
7  (1/60)  (10/10) N/A
24  (1/505)  (25/31) N/A
24  (1/506)  (29/31)  Wholemount images
8  (1/71)  (9/11) N/A
24  (1/505)  (27/31)  Wholemount images
4  (1/55)  (4/4) N/A
24  (1/505)  (27/31) N/A
16  (1/302)  (17/19) N/A
24  (1/505)  (27/31) N/A
24  (1/505)  (27/31)  Wholemount images
7  (1/61)  (9/10) N/A
8  (1/59)  (10/11) N/A
24  (1/505)  (27/31) N/A
24  (5/505)  (27/31)  Wholemount images
6  (1/60)  (9/9) N/A
24  (1/505)  (17/31)  Wholemount images
6  (1/60)  (9/9) N/A
24  (6/505)  (27/31) N/A
24  (1/505)  (27/31)  Wholemount images
6  (1/64)  (4/6) N/A
6  (1/64)  (4/6) N/A
6  (1/58)  (9/9) N/A
24  (1/503)  (16/31)  Wholemount images
16  (1/302)  (17/19) N/A
24  (1/503)  (15/31) N/A
24  (1/505)  (25/31)  Wholemount images
24  (1/505)  (25/31)  Wholemount images
2  (5/5) N/A
4  (1/55)  (2/4) N/A
4  (1/55)  (3/4) N/A
4  (1/55)  (4/5) N/A
24  (1/505)  (27/31) N/A
6  (1/60)  (9/9) N/A
12  (1/75)  (13/15) N/A
7  (1/60)  (10/10) N/A
24  (1/503)  (16/31) N/A
6  (1/60)  (9/9) N/A
4  (1/55)  (4/4) N/A
6  (1/55)  (9/9) N/A
4  (1/56)  (4/4) N/A
1  (7/39) N/A
6  (1/64)  (4/6) N/A
6  (1/57)  (8/8) N/A
10  (1/75)  (11/13) N/A
24  (1/505)  (25/31) N/A
11  (1/72)  (12/14) N/A
4  (1/55)  (4/4) N/A
24  (1/505)  (27/31)  Wholemount images
24  (1/505)  (27/31) N/A
4  (1/55)  (5/5) N/A
4  (1/55)  (5/5) N/A
6  (1/59)  (6/6) N/A
6  (1/60)  (9/9) N/A
4  (1/60)  (4/4) N/A
4  (1/60)  (4/4) N/A
16  (1/302)  (17/19) N/A
16  (1/302)  (17/19) N/A
6  (1/59)  (6/6) N/A
9  (1/71)  (10/12) N/A

 Associated Images

X-ray: XRay Images Whole Body Lateral Orientation
128 Images
X-ray: XRay Images Hind Leg and Hip
33 Images
Adult LacZ: LacZ Images Wholemount
276 Images
X-ray: XRay Images Whole Body Dorso Ventral
129 Images
X-ray: XRay Images Forepaw
76 Images
Adult LacZ: LacZ Images Section
170 Images
X-ray: XRay Images Hind Leg and Hip
10 Images
X-ray: XRay Images Whole Body Dorso Ventral
32 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
112 Images
Immunophenotyping: Panel B FCS file(s)
21 Images
Legacy Phenotype Associated Images

View all 91 images

 Disease Models

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 Histopathology

 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Nxnem1(IMPC)J Indel Mice
Nxntm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice, Tissue
Nxnem1(IMPC)Mbp Null reporter Mice, Tissue
Nxntm2a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Nxntm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells, Tissue
Nxnem1(IMPC)Bay Exon Deletion Mice, Tissue