Genes Phenotypes

Gene: Fadd

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Name
Fas (TNFRSF6)-associated via death domain
MGI ID
MGI:109324
Synonyms
Mort1/FADD
Viability
Homozygous - Lethal
View
3D Imaging
Other links
MGI   Ensembl  
Significant phenotypes (12) Measurements chart (222) All data table (428)
Expression & images (70) Disease models (0) Order (3)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
embryonic lethality prior to tooth bud stage Faddtm1e.1(KOMP)Wtsi HOM embryonic day 12.5 0.00
abnormal embryo size Faddtm1e.1(KOMP)Wtsi HOM embryonic day 9.5 0.00
abnormal neural tube closure Faddtm1e.1(KOMP)Wtsi HOM embryonic day 9.5 0.00
embryonic growth retardation Faddtm1e.1(KOMP)Wtsi HET embryonic day 9.5 0.00
small superior vagus ganglion Faddtm1e.1(KOMP)Wtsi HET postnatal 0.00
abnormal uterus morphology Faddtm1e.1(KOMP)Wtsi HET postnatal 0.00
abnormal midbrain development Faddtm1e.1(KOMP)Wtsi HET embryonic day 9.5 0.00
abnormal bone structure Faddtm1e.1(KOMP)Wtsi HET postnatal 2.08×10-05
abnormal neural tube closure Faddtm1e.1(KOMP)Wtsi HET embryonic day 9.5 0.00
preweaning lethality, complete penetrance Faddtm1e.1(KOMP)Wtsi HOM n/a 0.00
decreased bone mineral content Faddtm1e.1(KOMP)Wtsi HET postnatal 3.63×10-05
abnormal embryo size Faddtm1e.1(KOMP)Wtsi HET embryonic day 9.5 0.00

Download data as:  TSV  XLS

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Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No N/A
Brain 2 No N/A
Brainstem 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No N/A
Cerebral cortex 2 No N/A
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Heart 2 No N/A
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Kidney 2 No  (18/584)  (2/2)  Section images
Large intestine 2 No  (10/584)  (2/2) N/A
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No N/A
Ovary 2 No  (1/584) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/584) N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584)  (1/2)  Section images
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584)  (2/2) N/A
Spinal cord 2 No N/A
Spleen 2 No  (2/584)  (1/2)  Section images
Stomach 2 No  (12/584)  (1/2) N/A
Striatum 2 No N/A
Testis 2 No  (2/584)  (1/2)  Section images
Thymus 2 No N/A
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No N/A
Uterus 2 No N/A
Vascular system 2 No N/A
White adipose tissue 2 No N/A
LacZ Wholemount Images
LacZ Section Images
exocrine system (2)
Prostate gland expression
MA:0000404
immune system (2)
Spleen expression
MA:0000141
postnatal mouse (8)
Kidney expression
MA:0000368
reproductive system (4)
Prostate gland expression
MA:0000404
trunk (8)
Kidney expression
MA:0000368
urinary system (2)
Kidney expression
MA:0000368
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 2  (1/51) N/A
Brain 5  (6/485)  (2/5) N/A
Central nervous system ganglion 2  (1/51) N/A
Ear 5  (1/485) N/A
Embryo 5  (1/485)  (2/5) N/A
Eye 5  (1/485) N/A
Foot 5  (1/485) N/A
Forebrain 5  (1/485) N/A
Forelimb 5  (1/485) N/A
Gut 2  (1/50) N/A
Hand 5  (1/485) N/A
Head 5  (5/485) N/A
Heart 5  (1/485)  (2/5) N/A
Hindbrain 5  (6/485) N/A
Hindlimb 5  (1/485) N/A
Liver 5  (1/485) N/A
Lung 5  (1/485)  (2/5) N/A
Mandibular process 5  (1/485) N/A
Maxillary process 5  (1/485) N/A
Midbrain 5  (1/485) N/A
Nose 2  (1/51) N/A
Oral cavity 5  (1/485) N/A
Skeleton 2  (1/51) N/A
Skin 5  (1/485) N/A
Spinal cord 2  (1/50) N/A
Tail 5  (1/485) N/A
Tail somite 5  (1/485) N/A
Trachea 2  (1/50) N/A
Urinary system 2  (1/50)  (2/2) N/A

 Associated Images

X-ray: XRay Images Dorso Ventral
16 Images
X-ray: XRay Images Hind Leg and Hip
16 Images
X-ray: XRay Images Lateral Orientation
32 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
16 Images
Gross Pathology and Tissue Collection
8 Images
Adult LacZ: LacZ Images Section
8 Images
Gross Morphology Embryo E9.5
2 Images
Eye Morphology: Images Ophthalmoscopy
1 Images

 Disease Models

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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Faddtm1e(KOMP)Wtsi Targeted, non-conditional allele Mice
Faddtm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Faddtm1e.1(KOMP)Wtsi Mice, Tissue

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