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Gene: Fadd

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Name
Fas (TNFRSF6)-associated via death domain
MGI ID
MGI:109324
Synonyms
Mort1/FADD
Viability
Data available
Embryo viewer
3D Imaging
Other links
MGI   Ensembl  
Significant phenotypes (9) Measurements chart (226) All data table (656)
Expression & images (70) Disease models (0) Histopathology (0) Order (3)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
decreased bone mineral density Faddtm1e.1(KOMP)Wtsi HET Early adult 2.91×10-05
decreased bone mineral content Faddtm1e.1(KOMP)Wtsi HET Early adult 2.61×10-07
preweaning lethality, complete penetrance Faddtm1e.1(KOMP)Wtsi HOM   Early adult 0.00
increased total body fat amount Faddtm1e.1(KOMP)Wtsi HET Early adult 7.16×10-05
abnormal embryo size Faddtm1e.1(KOMP)Wtsi HOM E9.5 0.00
abnormal uterus morphology Faddtm1e.1(KOMP)Wtsi HET Early adult 0.00
prolonged PR interval Faddtm1e.1(KOMP)Wtsi HET   Early adult 3.17×10-06
abnormal neural tube closure Faddtm1e.1(KOMP)Wtsi HOM E9.5 0.00
decreased lean body mass Faddtm1e.1(KOMP)Wtsi HET Early adult 9.70×10-12

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (4/583) N/A
Aorta 2 No  (1/583) N/A
Brain 2 No  (4/583) N/A
Brainstem 2 No  (2/583) N/A
Cartilage tissue 2 No  (1/583) N/A
Cerebellum 2 No  (3/583) N/A
Cerebral cortex 2 No  (2/583) N/A
Esophagus 2 No  (7/407) N/A
Eye 2 No N/A
Heart 2 No  (2/583) N/A
Hippocampus 2 No  (3/583) N/A
Hypothalamus 2 No  (2/583) N/A
Kidney 2 No  (21/583)  (2/2)  Section images
Large intestine 2 No  (10/583)  (2/2) N/A
Liver 2 No N/A
Lower urinary tract 2 No  (1/583) N/A
Lung 2 No  (2/583) N/A
Lymph node 2 No  (1/583) N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No  (2/583) N/A
Ovary 2 No  (1/583) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/583) N/A
Peripheral nervous system 2 No  (2/583) N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/583) N/A
Prostate gland 2 No  (12/583)  (1/2)  Section images
Skeletal muscle 2 No N/A
Skin 2 No  (1/583) N/A
Small intestine 2 No  (9/583)  (2/2) N/A
Spinal cord 2 No  (3/583) N/A
Spleen 2 No  (3/583)  (1/2)  Section images
Stomach 2 No  (13/583)  (1/2) N/A
Striatum 2 No  (3/583) N/A
Testis 2 No  (6/583)  (1/2)  Section images
Thymus 2 No  (1/583) N/A
Thyroid gland 2 No  (17/583) N/A
Trachea 2 No  (3/583) N/A
Uterus 2 No N/A
Vascular system 2 No N/A
White adipose tissue 2 No N/A
LacZ Wholemount Images
LacZ Section Images
exocrine system (2)
Prostate gland expression
MA:0000404
immune system (2)
Spleen expression
MA:0000141
postnatal mouse (8)
Kidney expression
MA:0000368
reproductive system (4)
Prostate gland expression
MA:0000404
trunk (8)
Kidney expression
MA:0000368
urinary system (2)
Kidney expression
MA:0000368
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
2  (1/64) N/A
5  (6/505)  (2/5) N/A
2  (1/73) N/A
5  (1/505) N/A
5  (1/506)  (2/5) N/A
5  (1/505) N/A
5  (1/505) N/A
5  (1/505) N/A
5  (1/505) N/A
2  (1/59) N/A
5  (1/505) N/A
5  (5/505) N/A
5  (1/505)  (2/5) N/A
5  (6/505) N/A
5  (1/505) N/A
5  (1/503) N/A
5  (1/503)  (2/5) N/A
5  (1/505) N/A
5  (1/505) N/A
5  (1/505) N/A
2  (1/75) N/A
5  (1/503) N/A
2  (1/75) N/A
5  (1/505) N/A
2  (1/72) N/A
5  (1/505) N/A
5  (1/505) N/A
2  (1/59) N/A
2  (1/59)  (2/2) N/A

 Associated Images

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X-ray: XRay Images Whole Body Dorso Ventral
16 Images
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Embryo LacZ: LacZ images wholemount
46 Images
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X-ray: XRay Images Whole Body Lateral Orientation
32 Images
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Gross Pathology and Tissue Collection
8 Images
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Adult LacZ: LacZ Images Section
8 Images
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X-ray: XRay Images Skull Dorso Ventral Orientation
16 Images
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X-ray: XRay Images Hind Leg and Hip
16 Images
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Gross Morphology Embryo E9.5
2 Images
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Eye Morphology: Images Ophthalmoscopy
1 Images

 Disease Models

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 Histopathology

 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Faddtm1e(KOMP)Wtsi Targeted, non-conditional allele Mice
Faddtm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Faddtm1e.1(KOMP)Wtsi Mice, Tissue

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