Gene: Fadd

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Name
Fas (TNFRSF6)-associated via death domain
MGI ID
MGI:109324
Synonyms
Mort1/FADD
Embryo viewer
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal neural tube closure Faddtm1e.1(KOMP)Wtsi HOM E9.5 0.00
abnormal bone structure Faddtm1e.1(KOMP)Wtsi HET Early adult 2.08×10-05
preweaning lethality, complete penetrance Faddtm1e.1(KOMP)Wtsi HOM Early adult 0.00
abnormal uterus morphology Faddtm1e.1(KOMP)Wtsi HET Early adult 0.00
abnormal midbrain development Faddtm1e.1(KOMP)Wtsi HET E9.5 0.00
abnormal embryo size Faddtm1e.1(KOMP)Wtsi HET E9.5 0.00
decreased bone mineral content Faddtm1e.1(KOMP)Wtsi HET Early adult 3.63×10-05
embryonic lethality prior to tooth bud stage Faddtm1e.1(KOMP)Wtsi HOM E12.5 0.00
abnormal neural tube closure Faddtm1e.1(KOMP)Wtsi HET E9.5 0.00
embryonic growth retardation Faddtm1e.1(KOMP)Wtsi HET E9.5 0.00
abnormal embryo size Faddtm1e.1(KOMP)Wtsi HOM E9.5 0.00

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Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No N/A
Brain 2 No N/A
Brainstem 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No N/A
Cerebral cortex 2 No N/A
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Heart 2 No N/A
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Kidney 2 No  (18/584)  (2/2)  Section images
Large intestine 2 No  (10/584)  (2/2) N/A
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No N/A
Ovary 2 No  (1/584) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/584) N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584)  (1/2)  Section images
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584)  (2/2) N/A
Spinal cord 2 No N/A
Spleen 2 No  (2/584)  (1/2)  Section images
Stomach 2 No  (12/584)  (1/2) N/A
Striatum 2 No N/A
Testis 2 No  (2/584)  (1/2)  Section images
Thymus 2 No N/A
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No N/A
Uterus 2 No N/A
Vascular system 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 2  (1/61) N/A
Brain 5  (6/504)  (2/5) N/A
Central nervous system ganglion 2  (1/70) N/A
Ear 5  (1/504) N/A
Embryo 5  (1/505)  (2/5) N/A
Eye 5  (1/504) N/A
Foot 5  (1/504) N/A
Forebrain 5  (1/504) N/A
Forelimb 5  (1/504) N/A
Gut 2  (1/56) N/A
Hand 5  (1/503) N/A
Head 5  (5/504) N/A
Heart 5  (1/504)  (2/5) N/A
Hindbrain 5  (6/504) N/A
Hindlimb 5  (1/503) N/A
Liver 5  (1/504) N/A
Lung 5  (1/500)  (2/5) N/A
Mandibular process 5  (1/504) N/A
Maxillary process 5  (1/504) N/A
Midbrain 5  (1/504) N/A
Nose 2  (1/70) N/A
Oral cavity 5  (1/504) N/A
Skeleton 2  (1/70) N/A
Skin 5  (1/504) N/A
Spinal cord 2  (1/69) N/A
Tail 5  (1/504) N/A
Tail somite 5  (1/504) N/A
Trachea 2  (1/56) N/A
Urinary system 2  (1/56)  (2/2) N/A

 Associated Images

Adult LacZ: LacZ Images Section
8 Images
Gross Pathology and Tissue Collection
6 Images
X-ray: XRay Images Whole Body Lateral Orientation
32 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
16 Images
Embryo LacZ: LacZ images wholemount
46 Images
X-ray: XRay Images Whole Body Dorso Ventral
16 Images
X-ray: XRay Images Hind Leg and Hip
16 Images
Eye Morphology: Images Ophthalmoscopy
1 Images
Gross Morphology Embryo E9.5
2 Images

 Disease Models

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 Order Mouse and ES Cells

MGI Allele Allele Type Produced
Faddtm1e.1(KOMP)Wtsi Mice, Tissue
Faddtm1e(KOMP)Wtsi Targeted, non-conditional allele Mice
Faddtm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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