Genes Phenotypes

Gene: Mmp15

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Name
matrix metallopeptidase 15
MGI ID
MGI:109320
Synonyms
Membrane type 2-MMP MT2-MMP
Viability
Homozygous - Viable
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (9) Measurements chart (207) All data table (365)
Expression & images (51) Disease models (0) Order (2)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal esophagus morphology Mmp15tm1b(KOMP)Wtsi HOM Early adult 0.00
abnormal skin coloration Mmp15tm1b(KOMP)Wtsi HOM Early adult 8.40×10-07
enlarged spleen Mmp15tm1b(KOMP)Wtsi HOM Early adult 0.00
anophthalmia Mmp15tm1b(KOMP)Wtsi HOM Early adult 0.00
absent lymph nodes Mmp15tm1b(KOMP)Wtsi HOM Early adult 0.00
abnormal thyroid gland morphology Mmp15tm1b(KOMP)Wtsi HOM Early adult 0.00
abnormal trachea morphology Mmp15tm1b(KOMP)Wtsi HOM Early adult 0.00
athymia Mmp15tm1b(KOMP)Wtsi HOM Early adult 0.00
abnormal pancreas morphology Mmp15tm1b(KOMP)Wtsi HOM Early adult 0.00

Download data as:  TSV  XLS

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Viewing: all phenotypes
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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No N/A
Bone 2 No N/A
Brain 2 No  (2/2)  Wholemount images
Brainstem 2 No N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cecum 2 No  (12/379) N/A
Cerebellum 2 No N/A
Cerebral cortex 2 No N/A
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No  (2/2)  Wholemount images
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Kidney 2 No  (18/584) N/A
Large intestine 2 No  (10/584) N/A
Liver 2 No N/A
Lower urinary tract 2 No  (2/2)  Wholemount images
Lung 2 No  (2/2) N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Mesenteric lymph node 2 No N/A
Olfactory lobe 2 No  (2/2)  Wholemount images
Oral epithelium 2 No N/A
Ovary 2 No  (1/584) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/584)  (1/2)  Wholemount images
Parathyroid gland 2 No N/A
Peripheral nervous system 2 No  (2/2)  Wholemount images
Peyer's patch 2 No N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584)  (1/2)  Wholemount images
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No  (2/2)  Wholemount images
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584) N/A
Striatum 2 No  (2/2)  Wholemount images
Testis 2 No  (2/584)  Wholemount images
Thymus 2 No N/A
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No N/A
Trigeminal V nerve 2 No  (2/2)  Wholemount images
Urinary bladder 2 No  (2/2) N/A
Uterus 2 No N/A
Vas deferens 2 No  (15/388)  Wholemount images
Vascular system 2 No  (2/2)  Wholemount images
White adipose tissue 2 No N/A
LacZ Wholemount Images
Unassigned Top Level MA (1)
cardiovascular system (2)
Heart expression
Vascular System expression
MA:0000072
MA:0002718
exocrine system (1)
Lower Urinary Tract expression
Prostate gland expression
MA:0002636
MA:0000404
nervous system (4)
Peripheral Nervous System expression
Striatum expression
Brain expression
Olfactory Lobe expression
MA:0000218
MA:0000891
MA:0000168
MA:0002413
postnatal mouse (9)
Heart expression
Vascular System expression
MA:0000072
MA:0002718
reproductive system (2)
Lower Urinary Tract expression
Prostate gland expression
MA:0002636
MA:0000404
trunk (6)
Heart expression
Vascular System expression
MA:0000072
MA:0002718
urinary system (1)
Lower Urinary Tract expression
Prostate gland expression
MA:0002636
MA:0000404
LacZ Section Images
No Embryo expression data was found for this gene.

 Associated Images

X-ray: XRay Images Whole Body Dorso Ventral
11 Images
X-ray: XRay Images Whole Body Lateral Orientation
11 Images
X-ray: XRay Images Skull Lateral Orientation
11 Images
X-ray: XRay Images Forepaw
11 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
11 Images
Adult LacZ: LacZ Images Wholemount
10 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Mmp15tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice, Tissue
Mmp15tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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