Gene: Mapkapk2

MAP kinase-activated protein kinase 2
MK2 MAPKAP kinase 2 Rps6kc1
Homozygous - Viable
Other links
View data by physiological system
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal joint morphology Mapkapk2tm1b(EUCOMM)Hmgu HOM postnatal 1.39×10-05
abnormal bone structure Mapkapk2tm1b(EUCOMM)Hmgu HOM postnatal 5.41×10-09
abnormal clavicle morphology Mapkapk2tm1b(EUCOMM)Hmgu HOM postnatal 4.17×10-05
decreased bone mineral content Mapkapk2tm1b(EUCOMM)Hmgu HOM postnatal 1.56×10-07
increased circulating iron level Mapkapk2tm1b(EUCOMM)Hmgu HOM postnatal 1.13×10-05
abnormal optic disk morphology Mapkapk2tm1b(EUCOMM)Hmgu HOM postnatal 1.18×10-05

Download data as:  TSV  XLS

Filtered by: all phenotypes


IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 4 No  (2/584)  (3/4)  Wholemount images
Aorta 4 No  (4/4)  Wholemount images
Bone 4 No N/A
Brain 4 No  (3/4)  Wholemount images
Brainstem 4 No N/A
Brown adipose tissue 4 No  (4/4)  Wholemount images
Cartilage tissue 4 No N/A
Cerebellum 4 No N/A
Cerebral cortex 4 No N/A
Esophagus 4 No  (7/415)  (4/4)  Wholemount images
Eye 4 No N/A
Gall bladder 4 No  (4/4)  Wholemount images
Heart 4 No  (4/4)  Wholemount images
Hippocampus 4 No N/A
Hypothalamus 4 No N/A
Kidney 4 No  (18/584)  (4/4)  Wholemount images
Large intestine 4 No  (10/584)  (3/4)  Wholemount images
Liver 4 No N/A
Lower urinary tract 4 No  (4/4)  Wholemount images
Lung 4 No  (4/4)  Wholemount images
Lymph node 4 No N/A
Mammary gland 4 No N/A
Olfactory lobe 4 No N/A
Oral epithelium 4 No  (1/4) N/A
Ovary 4 No  (1/584)  (2/4)  Wholemount images
Oviduct 4 No  (2/4)  Wholemount images
Pancreas 4 No  (5/584) N/A
Parathyroid gland 4 No  (3/4)  Wholemount images
Peripheral nervous system 4 No N/A
Peyer's patch 4 No N/A
Pituitary gland 4 No N/A
Prostate gland 4 No  (12/584) N/A
Skeletal muscle 4 No N/A
Skin 4 No  Wholemount images
Small intestine 4 No  (9/584)  (4/4) N/A
Spinal cord 4 No N/A
Spleen 4 No  (2/584) N/A
Stomach 4 No  (12/584)  (4/4)  Wholemount images
Striatum 4 No N/A
Testis 4 No  (2/584)  (2/4)  Wholemount images
Thymus 4 No N/A
Thyroid gland 4 No  (15/584) N/A
Trachea 4 No  (1/4) N/A
Uterus 4 No  (2/4)  Wholemount images
Vascular system 4 No N/A
White adipose tissue 4 No N/A
No Embryo expression data was found for this gene.

 Associated Images

Echo: M-Mode Images
32 Images
X-ray: XRay Images Dorso Ventral
10 Images
X-ray: XRay Images Lateral Orientation
10 Images
Adult LacZ: LacZ Images Wholemount
15 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
4 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images

 Disease Models

No associations by disease annotation and gene orthology found.
Please visit the desktop version to see this section

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Mapkapk2tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Mapkapk2tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice

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