Psen2 | presenilin 2
Physiological systems
22 / 24 physiological systems tested
8 Significantly impacted by the knock-out
Reproductive system Immune system Endocrine/exocrine gland Limbs/digits/tail Nervous system Vision/eye Hematopoietic system Cardiovascular system
14 No significant impact
2 Not tested
Data collections
Gene metrics:9Significant phenotypes
4Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
abnormal thymus morphology | 1 supporting dataset | Psen2em1(IMPC)Ccpcz | homozygote | Early adult | N/A * | ||
abnormal retina morphology | 1 supporting dataset | Psen2em1(IMPC)Ccpcz | homozygote | Early adult | 7.52x10-5 | ||
abnormal digit morphology | 1 supporting dataset | Psen2em1(IMPC)Ccpcz | homozygote | Early adult | 4.99x10-8 | ||
abnormal heart morphology | 1 supporting dataset | Psen2em1(IMPC)Ccpcz | homozygote | Early adult | N/A * | ||
enlarged thymus | 1 supporting dataset | Psen2em1(IMPC)Ccpcz | homozygote | Early adult | N/A * | ||
hydrocephaly | 1 supporting dataset | Psen2em1(IMPC)Ccpcz | homozygote | Early adult | N/A * | ||
increased mean corpuscular hemoglobin | 1 supporting dataset | Psen2em1(IMPC)Ccpcz | homozygote | Early adult | 7.49x10-5 | ||
abnormal brain morphology | 1 supporting dataset | Psen2em1(IMPC)Ccpcz | homozygote | Early adult | N/A * | ||
abnormal seminal vesicle morphology | 1 supporting dataset | Psen2em1(IMPC)Ccpcz | homozygote | Early adult | N/A * |
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External links
No external links available for Psen2.
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Psen2em1(IMPC)Ccpcz | Exon Deletion | | mouse |
Psen2tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |