Sema4d | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
Physiological systems
19 / 24 physiological systems tested
8 Significantly impacted by the knock-out
Vision/eye Immune system Homeostasis/metabolism Adipose tissue Skeleton Hematopoietic system Cardiovascular system Growth/size/body region
11 No significant impact
5 Not tested
Data collections
Gene metrics:6Significant phenotypes
1Associated diseases
Expression examined in:46Adult tissues
42Embryo tissues
Human diseases caused by Sema4d mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
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