Pkn2 | protein kinase N2
Physiological systems
19 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Homeostasis/metabolism Behavior/neurological Mortality/aging
16 No significant impact
5 Not tested
Data collections
Gene metrics:8Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
decreased exploration in new environment | 1 supporting dataset | Pkn2tm1b(KOMP)Wtsi | heterozygote | Early adult | 3.63x10-11 | ||
increased circulating bilirubin level | 1 supporting dataset | Pkn2tm1b(KOMP)Wtsi | heterozygote | Early adult | 6.8x10-6 | ||
decreased circulating HDL cholesterol level | 1 supporting dataset | Pkn2tm1b(KOMP)Wtsi | heterozygote | Early adult | 3.79x10-5 | ||
preweaning lethality, complete penetrance | 1 supporting dataset | Pkn2tm1b(KOMP)Wtsi | homozygote | Early adult | N/A * | ||
decreased circulating cholesterol level | 1 supporting dataset | Pkn2tm1b(KOMP)Wtsi | heterozygote | Early adult | 1.59x10-5 | ||
decreased circulating unsaturated transferrin level | 1 supporting dataset | Pkn2tm1b(KOMP)Wtsi | heterozygote | Early adult | 1.18x10-7 | ||
increased startle reflex | 1 supporting dataset | Pkn2tm1b(KOMP)Wtsi | heterozygote | Early adult | 1.18x10-9 | ||
decreased circulating total protein level | 1 supporting dataset | Pkn2tm1b(KOMP)Wtsi | heterozygote | Early adult | 7.4x10-6 |
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External links
No external links available for Pkn2.
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Pkn2tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell mouse |
Pkn2tm1b(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
Pkn2tm1e(KOMP)Wtsi | Targeted, non-conditional allele | | es cell |
Pkn2tm2a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell |
Pkn2tm3a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell |
Pkn2tm3e(EUCOMM)Wtsi | Targeted, non-conditional allele | | es cell |