Gene: Eif4g2

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Name
eukaryotic translation initiation factor 4, gamma 2
MGI ID
MGI:109207
Synonyms
Nat1 DAP-5 Natm1 E130105L11Rik
Viability
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
embryonic lethality prior to organogenesis Eif4g2tm1b(KOMP)Wtsi HOM   E9.5 0.00
abnormal lens morphology Eif4g2tm1b(KOMP)Wtsi HET   Early adult 1.82×10-06
decreased bone mineral density Eif4g2tm1b(KOMP)Wtsi HET Early adult 9.47×10-10
decreased body length Eif4g2tm1b(KOMP)Wtsi HET Early adult 3.87×10-05
abnormal bone structure Eif4g2tm1b(KOMP)Wtsi HET Early adult 9.42×10-10
increased circulating alkaline phosphatase level Eif4g2tm1b(KOMP)Wtsi HET   Early adult 9.99×10-05
preweaning lethality, complete penetrance Eif4g2tm1b(KOMP)Wtsi HOM   Early adult 0.00
hyperactivity Eif4g2tm1b(KOMP)Wtsi HET   Early adult 1.56×10-05
decreased bone mineral content Eif4g2tm1b(KOMP)Wtsi HET Early adult 1.46×10-10
decreased circulating chloride level Eif4g2tm1b(KOMP)Wtsi HET   Early adult 1.02×10-06

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
2 No  (4/583) N/A
2 No  (1/583) N/A
2 No  (4/583) N/A
2 No  (2/583) N/A
2 No N/A
2 No  (1/583) N/A
2 No  (3/583) N/A
2 No  (2/583) N/A
2 No  (18/132) N/A
2 No  (7/407) N/A
2 No  (2/2)  Section images
2 No  (2/583)  (2/2)  Section images
2 No  (3/583) N/A
2 No  (2/583) N/A
2 No  (21/583)  (1/2)  Section images
2 No  (10/583) N/A
2 No N/A
2 No  (1/583) N/A
2 No  (2/583) N/A
2 No  (1/583) N/A
2 No N/A
2 No N/A
2 No  (2/583) N/A
2 No  (1/583) N/A
2 No N/A
2 No  (5/583) N/A
2 No  (2/583) N/A
2 No N/A
2 No  (1/583) N/A
2 No  (12/583) N/A
2 No N/A
2 No  (1/583) N/A
2 No  (9/583) N/A
2 No  (3/583) N/A
2 No  (3/583)  (2/2)  Section images
2 No  (13/583) N/A
2 No  (3/583) N/A
2 No  (2/130) N/A
2 No  (6/583) N/A
2 No N/A
2 No  (1/583) N/A
2 No  (17/583) N/A
2 No  (3/583) N/A
2 No N/A
2 No N/A
2 No N/A
2 No N/A
2 No N/A
No Embryo expression data was found for this gene.

 Associated Images

X-ray: XRay Images Whole Body Lateral Orientation
10 Images
Eye Morphology: Images Slit Lamp
1 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
X-ray: XRay Images Forepaw
10 Images
X-ray: XRay Images Whole Body Dorso Ventral
10 Images
X-ray: XRay Images Skull Lateral Orientation
10 Images
Original Image
Adult LacZ: LacZ Images Section
4 Images
Combined SHIRPA and Dysmorphology
2 Images
Electroretinography 2: Rod and cone PDF
5 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Eif4g2tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Eif4g2tm2a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Eif4g2tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice

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