Gene: Eif4g2

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Name
eukaryotic translation initiation factor 4, gamma 2
MGI ID
MGI:109207
Synonyms
DAP-5 Natm1 Nat1 E130105L11Rik
View
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
increased circulating alkaline phosphatase level Eif4g2tm1b(KOMP)Wtsi HET postnatal 1.74×10-05
embryonic lethality prior to organogenesis Eif4g2tm1b(KOMP)Wtsi HOM embryonic day 9.5 0.00
decreased bone mineral density Eif4g2tm1b(KOMP)Wtsi HET postnatal 6.16×10-06
decreased lean body mass Eif4g2tm1b(KOMP)Wtsi HET postnatal 5.21×10-05
hyperactivity Eif4g2tm1b(KOMP)Wtsi HET postnatal 2.05×10-05
decreased body length Eif4g2tm1b(KOMP)Wtsi HET postnatal 1.30×10-05
increased fasted circulating glucose level Eif4g2tm1b(KOMP)Wtsi HET postnatal 3.34×10-05
preweaning lethality, complete penetrance Eif4g2tm1b(KOMP)Wtsi HOM n/a 0.00
decreased circulating chloride level Eif4g2tm1b(KOMP)Wtsi HET postnatal 4.47×10-07
abnormal lens morphology Eif4g2tm1b(KOMP)Wtsi HET postnatal 3.94×10-05

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Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No N/A
Brain 2 No N/A
Brainstem 2 No N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No N/A
Cerebral cortex 2 No N/A
Epididymis 2 No  (18/134) N/A
Esophagus 2 No  (7/415) N/A
Eye 2 No  (2/2)  Section images
Heart 2 No  (2/2)  Section images
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Kidney 2 No  (18/584)  (1/2)  Section images
Large intestine 2 No  (10/584) N/A
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Midbrain 2 No N/A
Olfactory lobe 2 No N/A
Ovary 2 No  (1/584) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/584) N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No N/A
Spleen 2 No  (2/584)  (2/2)  Section images
Stomach 2 No  (12/584) N/A
Striatum 2 No N/A
Submandibular gland 2 No  (2/132) N/A
Testis 2 No  (2/584) N/A
Thalamus 2 No N/A
Thymus 2 No N/A
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No N/A
Urinary bladder 2 No N/A
Uterus 2 No N/A
Vascular system 2 No N/A
Vesicular gland 2 No N/A
White adipose tissue 2 No N/A
No Embryo expression data was found for this gene.

 Associated Images

Electroretinography 2: Rod and cone PDF
5 Images
X-ray: XRay Images Dorso Ventral
10 Images
X-ray: XRay Images Lateral Orientation
10 Images
X-ray: XRay Images Forepaw
10 Images
Original Image
Adult LacZ: LacZ Images Section
4 Images
X-ray: XRay Images Skull Lateral Orientation
10 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
Combined SHIRPA and Dysmorphology
2 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Eif4g2tm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Eif4g2tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Eif4g2tm2a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

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