Gene: Ltbp1

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Name
latent transforming growth factor beta binding protein 1
MGI ID
MGI:109151
Synonyms
b2b1000Clo LTBP-1 9430031G15Rik Ltbp1L
Viability
N/A
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal incisor morphology Ltbp1tm1a(EUCOMM)Wtsi HOM Early adult 1.73×10-06
abnormal snout morphology Ltbp1tm1a(EUCOMM)Wtsi HOM Early adult 3.25×10-12
decreased body length Ltbp1tm1a(EUCOMM)Wtsi HOM Early adult 1.33×10-11
decreased circulating HDL cholesterol level Ltbp1tm1a(EUCOMM)Wtsi HOM Early adult 1.88×10-06
decreased total body fat amount Ltbp1tm1a(EUCOMM)Wtsi HOM Early adult 1.79×10-12
decreased circulating iron level Ltbp1tm1a(EUCOMM)Wtsi HOM Early adult 1.65×10-06
decreased circulating aspartate transaminase level Ltbp1tm1a(EUCOMM)Wtsi HOM Early adult 8.48×10-09
decreased circulating serum albumin level Ltbp1tm1a(EUCOMM)Wtsi HOM Early adult 8.30×10-06
increased blood urea nitrogen level Ltbp1tm1a(EUCOMM)Wtsi HOM Early adult 7.49×10-05
increased hemoglobin content Ltbp1tm1a(EUCOMM)Wtsi HOM Early adult 1.34×10-06
decreased circulating cholesterol level Ltbp1tm1a(EUCOMM)Wtsi HOM Early adult 3.73×10-07
abnormal coat/hair pigmentation Ltbp1tm1a(EUCOMM)Wtsi HOM Early adult 9.98×10-05
decreased circulating alanine transaminase level Ltbp1tm1a(EUCOMM)Wtsi HOM Early adult 7.53×10-10
decreased body weight Ltbp1tm1a(EUCOMM)Wtsi HOM Early adult 1.92×10-18
increased leukocyte cell number Ltbp1tm1a(EUCOMM)Wtsi HET Early adult 2.13×10-05
decreased bone mineral content Ltbp1tm1a(EUCOMM)Wtsi HOM Early adult 1.35×10-06
decreased circulating LDL cholesterol level Ltbp1tm1a(EUCOMM)Wtsi HOM Early adult 2.53×10-08
decreased circulating total protein level Ltbp1tm1a(EUCOMM)Wtsi HOM Early adult 9.25×10-06

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 3 No  (2/584) N/A
Aorta 3 No N/A
Blood vessel 3 No  (3/3) N/A
Bone 3 No N/A
Brain 3 No N/A
Brainstem 3 No N/A
Brown adipose tissue 3 No N/A
Cartilage tissue 3 No N/A
Cerebellum 3 No N/A
Cerebral cortex 3 No N/A
Eye 3 No N/A
Gall bladder 3 No  (2/3) N/A
Heart 3 No  (2/3) N/A
Hippocampus 3 No N/A
Hypothalamus 3 No N/A
Kidney 3 No  (18/584)  (1/3) N/A
Large intestine 3 No  (10/584) N/A
Liver 3 No  (1/3) N/A
Lower urinary tract 3 No  (2/3) N/A
Lung 3 No  (1/3) N/A
Lymph node 3 No N/A
Mammary gland 3 No N/A
Esophagus 3 No N/A
Olfactory lobe 3 No N/A
Ovary 3 No  (1/584)  (2/3) N/A
Oviduct 3 No  (2/3) N/A
Pancreas 3 No  (5/584) N/A
Parathyroid gland 3 No N/A
Peripheral nervous system 3 No N/A
Peyer's patch 3 No N/A
Pituitary gland 3 No N/A
Prostate gland 3 No  (12/584) N/A
Skeletal muscle tissue 3 No N/A
Skin 3 No N/A
Small intestine 3 No  (9/584)  (1/3) N/A
Spinal cord 3 No N/A
Spleen 3 No  (2/584) N/A
Stomach 3 No  (12/584)  (3/3) N/A
Striatum 3 No N/A
Testis 3 No  (2/584)  (1/3) N/A
Thymus 3 No N/A
Thyroid gland 3 No  (15/584)  (1/3) N/A
Trachea 3 No  (2/3) N/A
Uterus 3 No  (1/3) N/A
White adipose tissue 3 No N/A
LacZ Section Images

View all 13 images

View all 10 images

No Embryo expression data was found for this gene.

 Associated Images

Legacy Phenotype Associated Images

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View all 7 images

 Disease Models

No associations by disease annotation and gene orthology found.
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MGI Allele Allele Type Produced
Ltbp1tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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