Ltbp1 | latent transforming growth factor beta binding protein 1
Physiological systems
19 / 24 physiological systems tested
9 Significantly impacted by the knock-out
Homeostasis/metabolism Pigmentation Integument Growth/size/body region Limbs/digits/tail Hematopoietic system Skeleton Craniofacial Cardiovascular system
10 No significant impact
5 Not tested
Data collections
Gene metrics:13Significant phenotypes
2Associated diseases
Expression examined in:45Adult tissues
0Embryo tissues
abnormal cranium morphology | 1 supporting dataset | Ltbp1tm1a(EUCOMM)Wtsi | homozygote | Early adult | 1.87x10-12 | ||
abnormal snout morphology | 1 supporting dataset | Ltbp1tm1a(EUCOMM)Wtsi | homozygote | Early adult | 3.25x10-12 | ||
decreased body weight | 4 supporting datasets | Ltbp1tm1a(EUCOMM)Wtsi | homozygote | Early adult | 1.03x10-13 | ||
abnormal ulna morphology | 1 supporting dataset | Ltbp1tm1a(EUCOMM)Wtsi | homozygote | Early adult | 1.33x10-11 | ||
abnormal incisor morphology | 1 supporting dataset | Ltbp1tm1a(EUCOMM)Wtsi | homozygote | Early adult | 1.73x10-6 | ||
abnormal radius morphology | 1 supporting dataset | Ltbp1tm1a(EUCOMM)Wtsi | homozygote | Early adult | 1.77x10-12 | ||
increased hemoglobin content | 1 supporting dataset | Ltbp1tm1a(EUCOMM)Wtsi | homozygote | Early adult | 8.23x10-5 | ||
increased circulating bilirubin level | 1 supporting dataset | Ltbp1tm1a(EUCOMM)Wtsi | heterozygote | Early adult | 3.64x10-5 | ||
abnormal tooth morphology | 1 supporting dataset | Ltbp1tm1a(EUCOMM)Wtsi | homozygote | Early adult | 2.65x10-10 | ||
vertebral fusion | 1 supporting dataset | Ltbp1tm1a(EUCOMM)Wtsi | homozygote | Early adult | 5.49x10-5 |
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External links
No external links available for Ltbp1.
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Ltbp1tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |