Gene: Sirpa

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Name
signal-regulatory protein alpha
MGI ID
MGI:108563
Synonyms
SHPS-1 P84 SIRP CD172a Ptpns1 Bit
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
decreased blood urea nitrogen level Sirpatm1b(EUCOMM)Hmgu HOM Early adult 2.08×10-05
enlarged spleen Sirpatm1b(EUCOMM)Hmgu HOM Early adult 0.00
increased lean body mass Sirpatm1b(EUCOMM)Hmgu HOM Early adult 2.23×10-06

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (2/2)  Wholemount images
Aorta 2 No N/A
Bone 2 No  (2/2) N/A
Brain 2 No  (2/2) N/A
Brainstem 2 No  (2/2) N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (2/2) N/A
Cecum 1 No  (12/379) N/A
Cerebellum 2 No  (2/2) N/A
Cerebral cortex 2 No  (2/2) N/A
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No N/A
Hippocampus 2 No  (2/2) N/A
Hypothalamus 2 No  (2/2) N/A
Kidney 2 No  (18/584)  (2/2) N/A
Large intestine 2 No  (10/584) N/A
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No N/A
Lymph node 2 No  (1/2) N/A
Mammary gland 2 No N/A
Mesenteric lymph node 2 No  (1/2)  Wholemount images
Olfactory lobe 2 No  (2/2) N/A
Oral epithelium 2 No N/A
Ovary 2 No  (1/584)  (1/2)  Wholemount images
Oviduct 2 No  (1/2)  Wholemount images
Pancreas 2 No  (5/584) N/A
Parathyroid gland 2 No N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No  (1/2) N/A
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584) N/A
Striatum 2 No  (2/2) N/A
Testis 2 No  (2/584)  (1/2) N/A
Thymus 2 No N/A
Thyroid gland 2 No  (15/584)  (2/2) N/A
Trachea 2 No  (2/2) N/A
Trigeminal V nerve 2 No N/A
Urinary bladder 2 No N/A
Uterus 2 No N/A
Vas deferens 2 No  (15/388) N/A
Vascular system 2 No N/A
White adipose tissue 2 No N/A
No Embryo expression data was found for this gene.

 Associated Images

Adult LacZ: LacZ Images Wholemount
3 Images
X-ray: XRay Images Whole Body Lateral Orientation
9 Images
X-ray: XRay Images Skull Lateral Orientation
9 Images
X-ray: XRay Images Whole Body Dorso Ventral
9 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
9 Images
Eye Morphology: VIP of left fundus
7 Images
Eye Morphology: VIP of right fundus
11 Images
X-ray: XRay Images Forepaw
9 Images
Eye Morphology: VIP of right eye
13 Images
Eye Morphology: VIP of left eye
4 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Sirpatm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Sirpatm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice, Tissue

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