Genes Phenotypes

Gene: Kif1b

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Name
kinesin family member 1B
MGI ID
MGI:108426
Synonyms
A530096N05Rik KIF1Bp130 KIF1Bp204 D4Mil1e N-3 kinesin Kif1b alpha Kif1b beta
Viability
Homozygous - Lethal
View
3D Imaging
Other links
MGI   Ensembl  
Significant phenotypes (13) Measurements chart (202) All data table (431)
Expression & images (80) Disease models (0) Order (2)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
increased circulating chloride level Kif1btm1b(KOMP)Wtsi HET postnatal 2.36×10-05
abnormal limb morphology Kif1btm1b(KOMP)Wtsi HOM embryonic day 18.5 0.00
preweaning lethality, complete penetrance Kif1btm1b(KOMP)Wtsi HOM n/a 0.00
increased circulating glucose level Kif1btm1b(KOMP)Wtsi HET postnatal 3.54×10-05
increased circulating sodium level Kif1btm1b(KOMP)Wtsi HET postnatal 3.86×10-10
hemorrhage Kif1btm1b(KOMP)Wtsi HOM embryonic day 18.5 0.00
decreased circulating glucose level Kif1btm1b(KOMP)Wtsi HET postnatal 3.54×10-05
abnormal behavioral response to light Kif1btm1b(KOMP)Wtsi HET postnatal 9.86×10-05
abnormal facial morphology Kif1btm1b(KOMP)Wtsi HOM embryonic day 18.5 0.00
abnormal outer ear morphology Kif1btm1b(KOMP)Wtsi HOM embryonic day 18.5 0.00
abnormal embryo size Kif1btm1b(KOMP)Wtsi HOM embryonic day 18.5 0.00
cyanosis Kif1btm1b(KOMP)Wtsi HET embryonic day 18.5 0.00
abnormal head shape Kif1btm1b(KOMP)Wtsi HOM embryonic day 18.5 0.00

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (2/2) N/A
Aorta 2 No  (2/2) N/A
Brain 2 No  (2/2) N/A
Brainstem 2 No  (2/2) N/A
Brown adipose tissue 2 No  (2/2) N/A
Cartilage tissue 2 No  (2/2) N/A
Cerebellum 2 No  (2/2) N/A
Cerebral cortex 2 No  (2/2) N/A
Epididymis 2 No  (18/134)  (1/2) N/A
Esophagus 2 No  (7/415)  (2/2) N/A
Eye 2 No  (2/2) N/A
Heart 2 No  (2/2) N/A
Hippocampus 2 No  (2/2) N/A
Hypothalamus 2 No  (2/2) N/A
Kidney 2 No  (18/584)  (2/2) N/A
Large intestine 2 No  (10/584)  (2/2) N/A
Liver 2 No  (2/2) N/A
Lower urinary tract 2 No N/A
Lung 2 No  (2/2) N/A
Lymph node 2 No  (2/2) N/A
Mammary gland 2 No  (1/2) N/A
Midbrain 2 No  (2/2) N/A
Olfactory lobe 2 No  (2/2) N/A
Ovary 2 No  (1/584)  (1/2) N/A
Oviduct 2 No  (1/2) N/A
Pancreas 2 No  (5/584)  (2/2) N/A
Peripheral nervous system 2 No  (2/2) N/A
Peyer's patch 2 No  (2/2) N/A
Pituitary gland 2 No  (2/2) N/A
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No  (2/2) N/A
Skin 2 No  (2/2) N/A
Small intestine 2 No  (9/584)  (2/2) N/A
Spinal cord 2 No  (2/2) N/A
Spleen 2 No  (2/584)  (2/2) N/A
Stomach 2 No  (12/584)  (2/2) N/A
Striatum 2 No  (2/2) N/A
Submandibular gland 2 No  (2/132)  (2/2) N/A
Testis 2 No  (2/584)  (1/2) N/A
Thalamus 2 No  (2/2) N/A
Thymus 2 No  (2/2) N/A
Thyroid gland 2 No  (15/584)  (2/2) N/A
Trachea 2 No  (2/2) N/A
Urinary bladder 2 No  (2/2) N/A
Uterus 2 No  (1/2) N/A
Vascular system 2 No  (2/2) N/A
Vesicular gland 2 No N/A
White adipose tissue 2 No  (2/2) N/A
LacZ Wholemount Images
LacZ Section Images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 1  (1/51)  (1/1) N/A
Brain 2  (6/485)  (2/3) N/A
Central nervous system ganglion 1  (1/51)  (1/1) N/A
Dorsal root ganglion 2  (1/47)  (1/2) N/A
Ear 2  (1/485) Image Only N/A
Embryo 2  (1/485)  (2/3)  Wholemount images
Eye 2  (1/485)  (2/3) N/A
Foot 2  (1/485)  (2/3) N/A
Forebrain 2  (1/485)  (2/3) N/A
Forelimb 2  (1/485)  (2/3) N/A
Fronto-nasal process 2  (1/48)  (1/2) N/A
Hand 2  (1/485)  (2/3) N/A
Head 2  (5/485)  (2/3) N/A
Heart 2  (1/485)  (2/3) N/A
Hindbrain 2  (6/485)  (2/3) N/A
Hindlimb 2  (1/485)  (2/3) N/A
Liver 2  (1/485) N/A
Lung 2  (1/485)  (1/3) N/A
Mandibular process 2  (1/485)  (2/3) N/A
Maxillary process 2  (1/485)  (2/3) N/A
Midbrain 2  (1/485)  (2/3) N/A
Nose 2  (1/51)  (2/2) N/A
Notochord 1  (1/47)  (1/1) N/A
Oral cavity 2  (1/485)  (1/3) N/A
Rib pre-cartilage condensation 1  (1/46)  (1/1) N/A
Skeleton 1  (1/51)  (1/1) N/A
Skin 2  (1/485)  (2/3) N/A
Spinal cord 2  (1/50)  (2/2) N/A
Tail 2  (1/485)  (2/3) N/A
Tail somite 2  (1/485)  (1/3) N/A
Thoracic vertebral cartilage condensation 1  (1/46)  (1/1) N/A
Vibrissa 1  (1/47)  (1/1) N/A
embryo or Unassigned (16)
Embryo expression
EMAPA:16039 embryo

 Associated Images

X-ray: XRay Images Skull Lateral Orientation
12 Images
X-ray: XRay Images Lateral Orientation
12 Images
Embryo LacZ: LacZ images wholemount
16 Images
X-ray: XRay Images Dorso Ventral
12 Images
X-ray: XRay Images Forepaw
12 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
12 Images
Combined SHIRPA and Dysmorphology
4 Images
Gross Morphology Embryo E18.5
2 Images

 Disease Models

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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Kif1btm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Kif1btm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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