Gene: Kif1b
Name kinesin family member 1B
Synonyms
- A530096N05Rik
- KIF1Bp130
- KIF1Bp204
- D4Mil1e
- N-3 kinesin
- Kif1b alpha
- Kif1b beta
Status
ES CellsMice
tm1aMice
tm1bphenotype data available
Links MGI:108426 Ensembl Gene Ensembl Orthologs My Genes
Viability Homozygous - Lethal
Phenotype associations for Kif1b
All Phenotypes Summary
Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Kif1b data for that phenotype.
Embryo Data:
3D Embryo Imaging
Significant Phenotypes
| System | Phenotype | Allele | Zyg | Sex | Life Stage | P Value | Data |
|---|---|---|---|---|---|---|---|
|
|
abnormal embryo size | Kif1btm1b(KOMP)Wtsi | HOM |
|
embryonic day 18.5 | 0.0 | |
|
|
abnormal facial morphology | Kif1btm1b(KOMP)Wtsi | HOM |
|
embryonic day 18.5 | 0.0 | |
|
|
abnormal head shape | Kif1btm1b(KOMP)Wtsi | HOM |
|
embryonic day 18.5 | 0.0 | |
|
|
abnormal limb morphology | Kif1btm1b(KOMP)Wtsi | HOM |
|
embryonic day 18.5 | 0.0 | |
|
|
abnormal outer ear morphology | Kif1btm1b(KOMP)Wtsi | HOM |
|
embryonic day 18.5 | 0.0 | |
|
|
cyanosis | Kif1btm1b(KOMP)Wtsi | HET |
|
embryonic day 18.5 | 0.0 | |
|
|
hemorrhage | Kif1btm1b(KOMP)Wtsi | HOM |
|
embryonic day 18.5 | 0.0 | |
|
|
preweaning lethality, complete penetrance | Kif1btm1b(KOMP)Wtsi | HOM |
|
n/a | 0.0 | |
|
|
increased circulating sodium level | Kif1btm1b(KOMP)Wtsi | HET |
|
postnatal | 3.86E-10 | |
|
|
increased circulating chloride level | Kif1btm1b(KOMP)Wtsi | HET |
|
postnatal | 2.36E-5 | |
|
|
decreased circulating glucose level | Kif1btm1b(KOMP)Wtsi | HET |
|
postnatal | 3.54E-5 | |
|
|
increased circulating glucose level | Kif1btm1b(KOMP)Wtsi | HET |
|
postnatal | 3.54E-5 | |
|
|
abnormal behavioral response to light | Kif1btm1b(KOMP)Wtsi | HET |
|
postnatal | 9.86E-5 |
Expression
IMPC lacZ Expression Data
Show expression table
Expression No Expression No Tissue Available Ambiguous
Show Wildtype Expression
| Anatomy | #HET Specimens | HOM Images? | WT Expr | Mutant Expr | Images |
|---|---|---|---|---|---|
| Adrenal gland | 2 | No | (2/415) | (2/2) | |
| Aorta | 2 | No | (2/2) | ||
| Brain | 2 | No | (2/2) | ||
| Brainstem | 2 | No | (2/2) | ||
| Brown adipose tissue | 2 | No | (2/2) | ||
| Cartilage tissue | 2 | No | (2/2) | ||
| Cerebellum | 2 | No | (2/2) | ||
| Cerebral cortex | 2 | No | (2/2) | ||
| Epididymis | 2 | No | (18/134) | (1/2) | |
| Esophagus | 2 | No | (7/415) | (2/2) | |
| Eye | 2 | No | (2/2) | ||
| Heart | 2 | No | (2/2) | ||
| Hippocampus | 2 | No | (2/2) | ||
| Hypothalamus | 2 | No | (2/2) | ||
| Kidney | 2 | No | (18/584) | (2/2) | |
| Large intestine | 2 | No | (10/584) | (2/2) | |
| Liver | 2 | No | (2/2) | ||
| Lower urinary tract | 2 | No | |||
| Lung | 2 | No | (2/2) | ||
| Lymph node | 2 | No | (2/2) | ||
| Mammary gland | 2 | No | (1/2) | ||
| Midbrain | 2 | No | (2/2) | ||
| Olfactory lobe | 2 | No | (2/2) | ||
| Ovary | 2 | No | (1/584) | (1/2) | |
| Oviduct | 2 | No | (1/2) | ||
| Pancreas | 2 | No | (5/584) | (2/2) | |
| Peripheral nervous system | 2 | No | (2/2) | ||
| Peyer's patch | 2 | No | (2/2) | ||
| Pituitary gland | 2 | No | (2/2) | ||
| Prostate gland | 2 | No | (12/584) | ||
| Skeletal muscle | 2 | No | (2/2) | ||
| Skin | 2 | No | (2/2) | ||
| Small intestine | 2 | No | (9/584) | (2/2) | |
| Spinal cord | 2 | No | (2/2) | ||
| Spleen | 2 | No | (2/584) | (2/2) | |
| Stomach | 2 | No | (12/584) | (2/2) | |
| Striatum | 2 | No | (2/2) | ||
| Submandibular gland | 2 | No | (2/132) | (2/2) | |
| Testis | 2 | No | (2/584) | (1/2) | |
| Thalamus | 2 | No | (2/2) | ||
| Thymus | 2 | No | (2/2) | ||
| Thyroid gland | 2 | No | (15/584) | (2/2) | |
| Trachea | 2 | No | (2/2) | ||
| Urinary bladder | 2 | No | (2/2) | ||
| Uterus | 2 | No | (1/2) | ||
| Vascular system | 2 | No | (2/2) | ||
| Vesicular gland | 2 | No | |||
| White adipose tissue | 2 | No | (2/2) |
Expression in Anatomogram
Tissues/organs lacZ+ expression
| endocrine system | respiratory system | digestive system | cardiovascular system | set of connective tissues | reproductive system | musculoskeletal system | adipose tissue | trunk | postnatal mouse | nervous system | sensory organ | immune system | exocrine system | integumental system | urinary system |
No expression image was found for this adult tab
Expression No Expression No Tissue Available Ambiguous
| Anatomy | #HET Specimens | WT Expr | Mutant Expr | Images |
|---|---|---|---|---|
| Axial skeleton | 1 | (1/51) | (1/1) | |
| Brain | 2 | (6/485) | (2/3) | |
| Central nervous system ganglion | 1 | (1/51) | (1/1) | |
| Dorsal root ganglion | 2 | (1/47) | (1/2) | |
| Ear | 2 | (1/485) | Image Only | |
| Embryo | 2 | (1/485) | (2/3) | |
| Eye | 2 | (1/485) | (2/3) | |
| Foot | 2 | (1/485) | (2/3) | |
| Forebrain | 2 | (1/485) | (2/3) | |
| Forelimb | 2 | (1/485) | (2/3) | |
| Fronto-nasal process | 2 | (1/48) | (1/2) | |
| Hand | 2 | (1/485) | (2/3) | |
| Head | 2 | (5/485) | (2/3) | |
| Heart | 2 | (1/485) | (2/3) | |
| Hindbrain | 2 | (6/485) | (2/3) | |
| Hindlimb | 2 | (1/485) | (2/3) | |
| Liver | 2 | (1/485) | ||
| Lung | 2 | (1/485) | (1/3) | |
| Mandibular process | 2 | (1/485) | (2/3) | |
| Maxillary process | 2 | (1/485) | (2/3) | |
| Midbrain | 2 | (1/485) | (2/3) | |
| Nose | 2 | (1/51) | (2/2) | |
| Notochord | 1 | (1/47) | (1/1) | |
| Oral cavity | 2 | (1/485) | (1/3) | |
| Rib pre-cartilage condensation | 1 | (1/46) | (1/1) | |
| Skeleton | 1 | (1/51) | (1/1) | |
| Skin | 2 | (1/485) | (2/3) | |
| Spinal cord | 2 | (1/50) | (2/2) | |
| Tail | 2 | (1/485) | (2/3) | |
| Tail somite | 2 | (1/485) | (1/3) | |
| Thoracic vertebral cartilage condensation | 1 | (1/46) | (1/1) | |
| Vibrissa | 1 | (1/47) | (1/1) |
Associated Images
Associated Images
-
X-ray: XRay Images Dorso Ventral
12 Images
-
Embryo LacZ: LacZ images wholemount
16 Images
-
X-ray: XRay Images Lateral Orientation
12 Images
-
X-ray: XRay Images Forepaw
12 Images
-
X-ray: XRay Images Skull Lateral Orientation
12 Images
-
X-ray: XRay Images Skull Dorso Ventral Orientation
12 Images
-
Combined SHIRPA and Dysmorphology
4 Images
-
Gross Morphology Embryo E18.5
2 Images
Order Mouse and ES Cells
| Targeting Detail | Product Ordering | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MGI Allele | Allele Type | Type Map Seq | Vector | ES Cell | Mouse | Tissue Enquiry | ||||||
| Kif1btm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) |
|
||||||||||
| Kif1btm1b(KOMP)Wtsi | Reporter-tagged deletion allele (post-Cre) |
|
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