Gene: Kif1b

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Name
kinesin family member 1B
MGI ID
MGI:108426
Synonyms
A530096N05Rik KIF1Bp130 KIF1Bp204 N-3 kinesin Kif1b beta Kif1b alpha D4Mil1e
Embryo viewer
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
increased circulating glucose level Kif1btm1b(KOMP)Wtsi HET Early adult 3.30×10-05
increased circulating sodium level Kif1btm1b(KOMP)Wtsi HET Early adult 3.33×10-10
cyanosis Kif1btm1b(KOMP)Wtsi HET E18.5 0.00
abnormal embryo size Kif1btm1b(KOMP)Wtsi HOM E18.5 0.00
abnormal head shape Kif1btm1b(KOMP)Wtsi HOM E18.5 0.00
abnormal limb morphology Kif1btm1b(KOMP)Wtsi HOM E18.5 0.00
preweaning lethality, complete penetrance Kif1btm1b(KOMP)Wtsi HOM Early adult 0.00
abnormal facial morphology Kif1btm1b(KOMP)Wtsi HOM E18.5 0.00
abnormal outer ear morphology Kif1btm1b(KOMP)Wtsi HOM E18.5 0.00
increased circulating chloride level Kif1btm1b(KOMP)Wtsi HET Early adult 2.48×10-05
hemorrhage Kif1btm1b(KOMP)Wtsi HOM E18.5 0.00
decreased circulating glucose level Kif1btm1b(KOMP)Wtsi HET Early adult 3.30×10-05

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (2/2) N/A
Aorta 2 No  (2/2) N/A
Brain 2 No  (2/2) N/A
Brainstem 2 No  (2/2) N/A
Brown adipose tissue 2 No  (2/2) N/A
Cartilage tissue 2 No  (2/2) N/A
Cerebellum 2 No  (2/2) N/A
Cerebral cortex 2 No  (2/2) N/A
Epididymis 2 No  (18/134)  (1/2) N/A
Esophagus 2 No  (7/415)  (2/2) N/A
Eye 2 No  (2/2) N/A
Heart 2 No  (2/2) N/A
Hippocampus 2 No  (2/2) N/A
Hypothalamus 2 No  (2/2) N/A
Kidney 2 No  (18/584)  (2/2) N/A
Large intestine 2 No  (10/584)  (2/2) N/A
Liver 2 No  (2/2) N/A
Lower urinary tract 2 No N/A
Lung 2 No  (2/2) N/A
Lymph node 2 No  (2/2) N/A
Mammary gland 2 No  (1/2) N/A
Midbrain 2 No  (2/2) N/A
Olfactory lobe 2 No  (2/2) N/A
Ovary 2 No  (1/584)  (1/2) N/A
Oviduct 2 No  (1/2) N/A
Pancreas 2 No  (5/584)  (2/2) N/A
Peripheral nervous system 2 No  (2/2) N/A
Peyer's patch 2 No  (2/2) N/A
Pituitary gland 2 No  (2/2) N/A
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No  (2/2) N/A
Skin 2 No  (2/2) N/A
Small intestine 2 No  (9/584)  (2/2) N/A
Spinal cord 2 No  (2/2) N/A
Spleen 2 No  (2/584)  (2/2) N/A
Stomach 2 No  (12/584)  (2/2) N/A
Striatum 2 No  (2/2) N/A
Submandibular gland 2 No  (2/132)  (2/2) N/A
Testis 2 No  (2/584)  (1/2) N/A
Thalamus 2 No  (2/2) N/A
Thymus 2 No  (2/2) N/A
Thyroid gland 2 No  (15/584)  (2/2) N/A
Trachea 2 No  (2/2) N/A
Urinary bladder 2 No  (2/2) N/A
Uterus 2 No  (1/2) N/A
Vascular system 2 No  (2/2) N/A
Vesicular gland 2 No N/A
White adipose tissue 2 No  (2/2) N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 1  (1/61)  (1/1) N/A
Brain 2  (6/504)  (2/3) N/A
Central nervous system ganglion 1  (1/70)  (1/1) N/A
Dorsal root ganglion 2  (1/57)  (1/2) N/A
Ear 2  (1/504) Image Only N/A
Embryo 2  (1/505)  (2/3)  Wholemount images
Eye 2  (1/504)  (2/3) N/A
Foot 2  (1/504)  (2/3) N/A
Forebrain 2  (1/504)  (2/3) N/A
Forelimb 2  (1/504)  (2/3) N/A
Fronto-nasal process 2  (1/58)  (1/2) N/A
Hand 2  (1/503)  (2/3) N/A
Head 2  (5/504)  (2/3) N/A
Heart 2  (1/504)  (2/3) N/A
Hindbrain 2  (6/504)  (2/3) N/A
Hindlimb 2  (1/503)  (2/3) N/A
Liver 2  (1/504) N/A
Lung 2  (1/500)  (1/3) N/A
Mandibular process 2  (1/504)  (2/3) N/A
Maxillary process 2  (1/504)  (2/3) N/A
Midbrain 2  (1/504)  (2/3) N/A
Nose 2  (1/70)  (2/2) N/A
Notochord 1  (1/57)  (1/1) N/A
Oral cavity 2  (1/504)  (1/3) N/A
Rib pre-cartilage condensation 1  (1/54)  (1/1) N/A
Skeleton 1  (1/70)  (1/1) N/A
Skin 2  (1/504)  (2/3) N/A
Spinal cord 2  (1/69)  (2/2) N/A
Tail 2  (1/504)  (2/3) N/A
Tail somite 2  (1/504)  (1/3) N/A
Thoracic vertebral cartilage condensation 1  (1/52)  (1/1) N/A
Vibrissa 1  (1/66)  (1/1) N/A

 Associated Images

Combined SHIRPA and Dysmorphology
4 Images
X-ray: XRay Images Forepaw
12 Images
X-ray: XRay Images Whole Body Lateral Orientation
12 Images
X-ray: XRay Images Skull Lateral Orientation
12 Images
X-ray: XRay Images Whole Body Dorso Ventral
12 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
12 Images
Gross Morphology Embryo E18.5
2 Images
Embryo LacZ: LacZ images wholemount
16 Images
Eye Morphology: Images Ophthalmoscopy
2 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Kif1btm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Kif1btm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice

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