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Gene: Kif1b

Order

Name kinesin family member 1B

Synonyms
  • KIF1Bp130
  • KIF1Bp204
  • Kif1b alpha
  • Kif1b beta
  • N-3 kinesin
  • A530096N05Rik
  • D4Mil1e

Status ES CellsMice
tm1aMice
tm1bphenotype data available

Links MGI:108426    Ensembl Gene    Ensembl Orthologs    My Genes   

Viability Homozygous - Lethal

Phenotype associations for Kif1b

Significant     Not Significant     Not tested    
All Phenotypes Summary

Based on automated MP annotations supported by experiments on knockout mouse models. Click on icons to go to all Kif1b data for that phenotype.

Embryo Data: 3D Embryo Imaging
Significant Phenotypes

System Phenotype Allele Zyg Sex Life Stage P Value Data
abnormal embryo size Kif1btm1b(KOMP)Wtsi HOM Female Male embryonic day 18.5 0.0
abnormal facial morphology Kif1btm1b(KOMP)Wtsi HOM Female Male embryonic day 18.5 0.0
abnormal head shape Kif1btm1b(KOMP)Wtsi HOM Female Male embryonic day 18.5 0.0
abnormal limb morphology Kif1btm1b(KOMP)Wtsi HOM Female Male embryonic day 18.5 0.0
abnormal outer ear morphology Kif1btm1b(KOMP)Wtsi HOM Female Male embryonic day 18.5 0.0
cyanosis Kif1btm1b(KOMP)Wtsi HET Female embryonic day 18.5 0.0
hemorrhage Kif1btm1b(KOMP)Wtsi HOM Female Male embryonic day 18.5 0.0
preweaning lethality, complete penetrance Kif1btm1b(KOMP)Wtsi HOM Female Male n/a 0.0
increased circulating sodium level Kif1btm1b(KOMP)Wtsi HET Female Male postnatal 3.65E-10
increased circulating chloride level Kif1btm1b(KOMP)Wtsi HET Female Male postnatal 2.38E-5
decreased circulating glucose level Kif1btm1b(KOMP)Wtsi HET Male postnatal 3.52E-5
increased circulating glucose level Kif1btm1b(KOMP)Wtsi HET Female postnatal 3.52E-5
abnormal behavioral response to light Kif1btm1b(KOMP)Wtsi HET Female postnatal 6.39E-5
hyperactivity Kif1btm1b(KOMP)Wtsi HET Female postnatal 8.48E-5

Download data as: TSV XLS



Expression

IMPC lacZ Expression Data
Show expression table

 Expression    No Expression    No Tissue Available    Ambiguous  

Show Wildtype Expression
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No (5/393) (2/2)
Aorta 2 No (1/562) (2/2)
Brain 2 No (6/562) (2/2)
Brainstem 2 No (4/562) (2/2)
Brown adipose tissue 2 No (2/2)
Cartilage tissue 2 No (1/562) (2/2)
Cerebellum 2 No (4/562) (2/2)
Cerebral cortex 2 No (5/562) (2/2)
Epididymis 2 No (4/106) (1/2)
Esophagus 2 No (2/393) (2/2)
Eye 2 No (1/562) (2/2)
Heart 2 No (3/562) (2/2)
Hippocampus 2 No (5/562) (2/2)
Hypothalamus 2 No (4/562) (2/2)
Kidney 2 No (20/562) (2/2)
Large intestine 2 No (12/562) (2/2)
Liver 2 No (2/2)
Lower urinary tract 2 No (3/562)
Lung 2 No (3/562) (2/2)
Lymph node 2 No (1/562) (2/2)
Mammary gland 2 No (1/2)
Midbrain 2 No (2/2)
Olfactory lobe 2 No (4/393) (2/2)
Ovary 2 No (1/562) (1/2)
Oviduct 2 No (2/562) (1/2)
Pancreas 2 No (6/562) (2/2)
Peripheral nervous system 2 No (3/562) (2/2)
Peyer's patch 2 No (1/393) (2/2)
Pituitary gland 2 No (1/562) (2/2)
Prostate gland 2 No (5/562)
Skeletal muscle 2 No (2/2)
Skin 2 No (1/562) (2/2)
Small intestine 2 No (11/562) (2/2)
Spinal cord 2 No (3/562) (2/2)
Spleen 2 No (4/562) (2/2)
Stomach 2 No (9/562) (2/2)
Striatum 2 No (4/562) (2/2)
Submandibular gland 2 No (1/104) (2/2)
Testis 2 No (4/562) (1/2)
Thalamus 2 No (2/2)
Thymus 2 No (2/2)
Thyroid gland 2 No (16/562) (2/2)
Trachea 2 No (3/562) (2/2)
Urinary bladder 2 No (2/2)
Uterus 2 No (2/562) (1/2)
Vascular system 2 No (1/393) (2/2)
Vesicular gland 2 No
White adipose tissue 2 No (2/2)
Expression in Anatomogram

Tissues/organs lacZ+ expression

    endocrine system
    respiratory system
    digestive system
    cardiovascular system
    set of connective tissues
    reproductive system
    musculoskeletal system
    adipose tissue
    trunk
    postnatal mouse
    nervous system
    sensory organ
    immune system
    exocrine system
    integumental system
    urinary system
No expression image was found for this adult tab

 Expression    No Expression    No Tissue Available    Ambiguous  

Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 1 (1/47) (1/1)
Brain 2 (6/482) (2/3)
Central nervous system ganglion 1 (1/47) (1/1)
Dorsal root ganglion 2 (1/45) (1/2)
Ear 2 (1/482) Image Only
Embryo 2 (1/482) (2/3)
Eye 2 (1/482) (2/3)
Foot 2 (1/482) (2/3)
Forebrain 2 (1/482) (2/3)
Forelimb 2 (1/482) (2/3)
Fronto-nasal process 2 (1/46) (1/2)
Hand 2 (1/482) (2/3)
Head 2 (5/482) (2/3)
Heart 2 (1/482) (2/3)
Hindbrain 2 (6/482) (2/3)
Hindlimb 2 (1/482) (2/3)
Liver 2 (1/482)
Lung 2 (1/482) (1/3)
Mandibular process 2 (1/482) (2/3)
Maxillary process 2 (1/482) (2/3)
Midbrain 2 (1/482) (2/3)
Nose 2 (1/47) (2/2)
Notochord 1 (1/45) (1/1)
Oral cavity 2 (1/482) (1/3)
Rib pre-cartilage condensation 1 (1/44) (1/1)
Skeleton 1 (1/47) (1/1)
Skin 2 (1/482) (2/3)
Spinal cord 2 (1/46) (2/2)
Tail 2 (1/482) (2/3)
Tail somite 2 (1/482) (1/3)
Thoracic vertebral cartilage condensation 1 (1/44) (1/1)
Vibrissa 1 (1/45) (1/1)


Associated Images

Associated Images
  • Embryo LacZ: LacZ images wholemount
    16 Images
  • X-ray: XRay Images Skull Lateral Orientation
    12 Images
  • Combined SHIRPA and Dysmorphology
    4 Images
  • X-ray: XRay Images Lateral Orientation
    12 Images
  • X-ray: XRay Images Dorso Ventral
    12 Images
  • X-ray: XRay Images Forepaw
    12 Images
  • Gross Morphology Embryo E18.5
    2 Images
  • X-ray: XRay Images Skull Dorso Ventral Orientation
    12 Images

Disease Models

Order Mouse and ES Cells

Targeting Detail Product Ordering
MGI Allele Allele Type Type Map Seq Vector ES Cell Mouse Tissue Enquiry
Kif1btm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential)
Vector
Gene
Kif1btm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre)
Vector
Gene