Genes Phenotypes

Gene: Kif1b

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Name
kinesin family member 1B
MGI ID
MGI:108426
Synonyms
A530096N05Rik KIF1Bp130 KIF1Bp204 D4Mil1e N-3 kinesin Kif1b alpha Kif1b beta
Viability
Homozygous - Lethal
View
3D Imaging
Other links
MGI   Ensembl  
Significant phenotypes (13) Measurements chart (202) All data table (431)
Expression & images (80) Disease models (0) Order (2)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal limb morphology Kif1btm1b(KOMP)Wtsi HOM embryonic day 18.5 0.00
abnormal behavioral response to light Kif1btm1b(KOMP)Wtsi HET postnatal 9.86×10-05
preweaning lethality, complete penetrance Kif1btm1b(KOMP)Wtsi HOM n/a 0.00
increased circulating glucose level Kif1btm1b(KOMP)Wtsi HET postnatal 3.54×10-05
abnormal embryo size Kif1btm1b(KOMP)Wtsi HOM embryonic day 18.5 0.00
abnormal head shape Kif1btm1b(KOMP)Wtsi HOM embryonic day 18.5 0.00
increased circulating chloride level Kif1btm1b(KOMP)Wtsi HET postnatal 2.36×10-05
abnormal outer ear morphology Kif1btm1b(KOMP)Wtsi HOM embryonic day 18.5 0.00
abnormal facial morphology Kif1btm1b(KOMP)Wtsi HOM embryonic day 18.5 0.00
decreased circulating glucose level Kif1btm1b(KOMP)Wtsi HET postnatal 3.54×10-05
hemorrhage Kif1btm1b(KOMP)Wtsi HOM embryonic day 18.5 0.00
cyanosis Kif1btm1b(KOMP)Wtsi HET embryonic day 18.5 0.00
increased circulating sodium level Kif1btm1b(KOMP)Wtsi HET postnatal 3.86×10-10

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (2/2) N/A
Aorta 2 No  (2/2) N/A
Brain 2 No  (2/2) N/A
Brainstem 2 No  (2/2) N/A
Brown adipose tissue 2 No  (2/2) N/A
Cartilage tissue 2 No  (2/2) N/A
Cerebellum 2 No  (2/2) N/A
Cerebral cortex 2 No  (2/2) N/A
Epididymis 2 No  (18/134)  (1/2) N/A
Esophagus 2 No  (7/415)  (2/2) N/A
Eye 2 No  (2/2) N/A
Heart 2 No  (2/2) N/A
Hippocampus 2 No  (2/2) N/A
Hypothalamus 2 No  (2/2) N/A
Kidney 2 No  (18/584)  (2/2) N/A
Large intestine 2 No  (10/584)  (2/2) N/A
Liver 2 No  (2/2) N/A
Lower urinary tract 2 No N/A
Lung 2 No  (2/2) N/A
Lymph node 2 No  (2/2) N/A
Mammary gland 2 No  (1/2) N/A
Midbrain 2 No  (2/2) N/A
Olfactory lobe 2 No  (2/2) N/A
Ovary 2 No  (1/584)  (1/2) N/A
Oviduct 2 No  (1/2) N/A
Pancreas 2 No  (5/584)  (2/2) N/A
Peripheral nervous system 2 No  (2/2) N/A
Peyer's patch 2 No  (2/2) N/A
Pituitary gland 2 No  (2/2) N/A
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No  (2/2) N/A
Skin 2 No  (2/2) N/A
Small intestine 2 No  (9/584)  (2/2) N/A
Spinal cord 2 No  (2/2) N/A
Spleen 2 No  (2/584)  (2/2) N/A
Stomach 2 No  (12/584)  (2/2) N/A
Striatum 2 No  (2/2) N/A
Submandibular gland 2 No  (2/132)  (2/2) N/A
Testis 2 No  (2/584)  (1/2) N/A
Thalamus 2 No  (2/2) N/A
Thymus 2 No  (2/2) N/A
Thyroid gland 2 No  (15/584)  (2/2) N/A
Trachea 2 No  (2/2) N/A
Urinary bladder 2 No  (2/2) N/A
Uterus 2 No  (1/2) N/A
Vascular system 2 No  (2/2) N/A
Vesicular gland 2 No N/A
White adipose tissue 2 No  (2/2) N/A
LacZ Wholemount Images
LacZ Section Images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 1  (1/51)  (1/1) N/A
Brain 2  (6/485)  (2/3) N/A
Central nervous system ganglion 1  (1/51)  (1/1) N/A
Dorsal root ganglion 2  (1/47)  (1/2) N/A
Ear 2  (1/485) Image Only N/A
Embryo 2  (1/485)  (2/3)  Wholemount images
Eye 2  (1/485)  (2/3) N/A
Foot 2  (1/485)  (2/3) N/A
Forebrain 2  (1/485)  (2/3) N/A
Forelimb 2  (1/485)  (2/3) N/A
Fronto-nasal process 2  (1/48)  (1/2) N/A
Hand 2  (1/485)  (2/3) N/A
Head 2  (5/485)  (2/3) N/A
Heart 2  (1/485)  (2/3) N/A
Hindbrain 2  (6/485)  (2/3) N/A
Hindlimb 2  (1/485)  (2/3) N/A
Liver 2  (1/485) N/A
Lung 2  (1/485)  (1/3) N/A
Mandibular process 2  (1/485)  (2/3) N/A
Maxillary process 2  (1/485)  (2/3) N/A
Midbrain 2  (1/485)  (2/3) N/A
Nose 2  (1/51)  (2/2) N/A
Notochord 1  (1/47)  (1/1) N/A
Oral cavity 2  (1/485)  (1/3) N/A
Rib pre-cartilage condensation 1  (1/46)  (1/1) N/A
Skeleton 1  (1/51)  (1/1) N/A
Skin 2  (1/485)  (2/3) N/A
Spinal cord 2  (1/50)  (2/2) N/A
Tail 2  (1/485)  (2/3) N/A
Tail somite 2  (1/485)  (1/3) N/A
Thoracic vertebral cartilage condensation 1  (1/46)  (1/1) N/A
Vibrissa 1  (1/47)  (1/1) N/A
embryo or Unassigned (16)
Embryo expression
EMAPA:16039 embryo

 Associated Images

X-ray: XRay Images Forepaw
12 Images
X-ray: XRay Images Lateral Orientation
12 Images
X-ray: XRay Images Skull Lateral Orientation
12 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
12 Images
X-ray: XRay Images Dorso Ventral
12 Images
Embryo LacZ: LacZ images wholemount
16 Images
Combined SHIRPA and Dysmorphology
4 Images
Gross Morphology Embryo E18.5
2 Images

 Disease Models

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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Kif1btm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Kif1btm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice

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