Gene: Apbb2

Log in to follow

Name
amyloid beta (A4) precursor protein-binding, family B, member 2
MGI ID
MGI:108405
Synonyms
TR2L Rirl1 Zfra 2310007D03Rik FE65L1
Embryo viewer
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
preweaning lethality, incomplete penetrance Apbb2tm1.1(KOMP)Vlcg HOM Early adult 0.00
decreased circulating insulin level Apbb2tm1.1(KOMP)Vlcg HET Early adult 5.18×10-10
abnormal glucose tolerance Apbb2tm1.1(KOMP)Vlcg HET Early adult 4.01×10-05
abnormal skin morphology Apbb2tm1.1(KOMP)Vlcg HET Early adult 0.00
abnormal eye morphology Apbb2tm1.1(KOMP)Vlcg HET Early adult 0.00
abnormal adipose tissue amount Apbb2tm1.1(KOMP)Vlcg HET Early adult 1.85×10-05
abnormal mean corpuscular hemoglobin Apbb2tm1.1(KOMP)Vlcg HET Early adult 2.92×10-05

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (3/589)  (1/2)  Section images
Aorta 2 No  (1/589) N/A
Blood 2 No N/A
Bone marrow 2 No N/A
Brain 2 No  (3/589) N/A
Brainstem 2 No  (2/589) N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cecum 2 No  (12/379) N/A
Cerebellum 2 No  (3/589)  (2/2)  Section images
Cerebral cortex 2 No  (2/589) N/A
Chest bone 2 No N/A
Colon 2 No  (12/127)  (2/2)  Section images
Diaphragm 2 No N/A
Duodenum 2 No  (2/127) N/A
Epididymis 2 No  (18/134)  (1/2)  Section images
Esophagus 2 No  (7/415)  (1/2)  Section images
Eye 2 No  (1/2)  Section images
Gall bladder 2 No N/A
Gonadal fat pad 2 No N/A
Harderian gland 2 No  (1/2)  Section images
Heart 2 No  (1/589) N/A
Hindlimb 2 No N/A
Hippocampus 2 No  (3/589) N/A
Hypothalamus 2 No  (2/589) N/A
Ileum 2 No  (14/127)  (1/2)  Section images
Jejunum 2 No  (6/127)  (1/2)  Section images
Kidney 2 No  (20/589)  (2/2)  Section images
Large intestine 2 No  (10/589) N/A
Liver 2 No  (1/2)  Section images
Lower urinary tract 2 No  (1/589) N/A
Lung 2 No  (1/589) N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Mesenteric adipose tissue 2 No  (1/2)  Section images
Mesenteric lymph node 2 No N/A
Midbrain 2 No  (2/2)  Section images
Olfactory lobe 2 No  (2/589)  (2/2)  Section images
Ovary 2 No  (1/589) N/A
Oviduct 2 No  (1/2)  Section images
Pancreas 2 No  (5/589)  (2/2)  Section images
Parathyroid gland 2 No  (2/2)  Section images
Parotid gland 2 No N/A
Penis 2 No  (1/2)  Section images
Peripheral nervous system 2 No  (1/589) N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/589)  Section images
Prostate gland 2 No  (12/589)  (1/2)  Section images
Quadriceps 2 No  (1/2)  Section images
Sciatic nerve 2 No N/A
Skeletal muscle 2 No N/A
Skin 2 No  (2/2)  Section images
Small intestine 2 No  (9/589) N/A
Spinal cord 2 No  (2/589)  (1/2)  Section images
Spleen 2 No  (2/589)  (2/2)  Section images
Stomach 2 No  (13/589)  (1/2)  Section images
Stomach pyloric region 2 No N/A
Striatum 2 No  (3/589) N/A
Sublingual gland 2 No  (1/2)  Section images
Submandibular gland 2 No  (2/132) N/A
Testis 2 No  (5/589)  (1/2)  Section images
Thymus 2 No  (1/2)  Section images
Thyroid gland 2 No  (16/589) N/A
Tongue 2 No  (5/127)  (2/2)  Section images
Trachea 2 No  (2/589)  (2/2)  Section images
Trigeminal V nerve 2 No  (1/2)  Section images
Urinary bladder 2 No  (2/2)  Section images
Uterus 2 No  (1/2)  Section images
Vagina 2 No  (1/2)  Section images
Vas deferens 2 No  (15/388)  (1/2)  Section images
Vascular system 2 No N/A
Vesicular gland 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Heart atrium 1  (1/61) N/A
Axial skeleton 6  (1/65)  (6/7) N/A
Brain 6  (6/506)  (7/7) N/A
Central nervous system ganglion 6  (1/74)  (7/7) N/A
Dorsal root ganglion 6  (1/61)  (7/7) N/A
Ear 6  (1/506)  (1/7) N/A
Embryo 6  (1/507)  (7/7) N/A
Outer ear 1  (1/70)  (1/2) N/A
Eye 6  (1/506)  (1/7) N/A
Foot 6  (1/506)  (1/7) N/A
Forebrain 6  (1/506) N/A
Forelimb 6  (1/506)  (7/7) N/A
Fronto-nasal process 6  (1/62)  (7/7) N/A
Gut 6  (1/60)  (2/7) N/A
Hand 6  (1/505)  (2/7) N/A
Head 6  (5/506)  (1/7) N/A
Head mesenchyme 6  (1/61)  (1/7) N/A
Heart 6  (1/506) N/A
Heart ventricle 1  (1/61) N/A
Hindbrain 6  (6/506)  (6/7) N/A
Hindlimb 6  (1/505)  (6/7) N/A
Liver 6  (1/506) N/A
Lung 6  (1/502)  (7/7) N/A
Mandibular process 6  (1/506) N/A
Maxillary process 6  (1/506)  (1/7) N/A
Meckel's cartilage 6 N/A
Midbrain 6  (1/506)  (7/7) N/A
Nasal septum 6  (1/61)  (7/7) N/A
Nose 6  (1/74)  (7/7) N/A
Notochord 6  (1/61) N/A
Oral cavity 6  (1/506)  (1/7) N/A
Outflow tract 1  (1/61) N/A
Pericardium 1  (1/56)  (1/2) N/A
Skeleton 6  (1/74)  (7/7) N/A
Skin 6  (1/506) N/A
Spinal cord 6  (1/73)  (7/7) N/A
Tail 6  (1/506) N/A
Tail somite 6  (1/506) N/A
Tongue 6  (1/56) N/A
Trunk mesenchyme 6  (1/61) N/A
Vibrissa 6  (1/70) N/A

 Associated Images

Adult LacZ: LacZ Images Section
96 Images
X-ray: XRay Images Whole Body Dorso Ventral
10 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images

 Disease Models

No associations by disease annotation and gene orthology found.
Please visit the desktop version to see this section

 Order Mouse and ES Cells

This service may be affected by the Covid-19 pandemic. See how

MGI Allele Allele Type Produced
Apbb2tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice, Tissue
Apbb2tm448183(L1L2_GT1_LF2A_LacZ_BetactP_neo) Targeting vectors
Apbb2tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter