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Gene: Sparcl1 MGI:108110

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Gene Summary

Name:
SPARC-like 1
Synonyms:
Ecm2,  Sc1,  hevin,  mast9

Order Alleles

IMPC Data Collections

IMPC Phenotype Summary

Significant
Not Significant
Not tested

View all our phenotype data below

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

Phenotype System Allele Zyg Sex Life Stage P Value
abnormal uterus morphology Sparcl1em1(IMPC)Mbp HOM Early adult 0.00
hydrometra Sparcl1em1(IMPC)Mbp HOM Early adult 0.00

Download data as:  TSV  XLS

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Viewing: all phenotypes
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Viewing: all phenotypes

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

X-ray

XRay Images Whole Body Dorso Ventral

30 Images

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X-ray

XRay Images Whole Body Lateral Orientation

10 Images

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Human diseases caused by Sparcl1 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

No human diseases associated to this gene by orthology or annotation.

The table below shows human diseases predicted to be associated to Sparcl1 by phenotypic similarity.

Disease Similarity of
phenotypes		 Matching phenotypes Source
Uterine Anomalies
Bicornuate uterus, Abnormality of the uterus OMIM:192000
Ovarian Dysgenesis 6
Hypoplasia of the uterus, Hypergonadotropic hypogonadism OMIM:618078
Pontocerebellar Hypoplasia, Type 4
Loss of Purkinje cells in the cerebellar vermis, Gliosis, Hypoplasia of the pons, Cerebellar hypo... OMIM:225753
Premature Ovarian Failure 3
Hypoplasia of the uterus OMIM:608996
Testicular Regression Syndrome
Abnormal morphology of female internal genitalia, Decreased testicular size, Agonadism, Male pseu... ORPHA:983
Huntington Disease
Cerebellar atrophy, Gliosis OMIM:143100
Diabetes Insipidus, Neurohypophyseal
Gliosis OMIM:125700
Autoinflammatory Disease, Familial, Behcet-Like 3
Vaginal mucosal ulceration OMIM:618287
Amyotrophic Lateral Sclerosis 15 With Or Without Frontotemporal Dementia
Gliosis, Amyotrophic lateral sclerosis OMIM:300857
46,Xy Sex Reversal 3
Clitoral hypertrophy, Gonadal dysgenesis, Ambiguous genitalia, Exaggerated rugosity of the labia ... OMIM:612965
Spinocerebellar Ataxia, Autosomal Recessive 2
Cerebellar hypoplasia, Cerebellar vermis atrophy, Dilated fourth ventricle, Gliosis OMIM:213200
Developmental And Epileptic Encephalopathy 71
Gliosis OMIM:618328
Immunodeficiency 83, Susceptibility To Viral Infections
Gliosis OMIM:613002
Caudal Duplication Anomaly
Uterus didelphys OMIM:607864
46,Xy Sex Reversal 11
Vanishing testis, Aplasia of the uterus, Urogenital sinus anomaly, Gonadal dysgenesis with female... OMIM:273250
46,Xx Ovotesticular Difference Of Sex Development
Small scrotum, Hypospadias, Bifid scrotum, Abnormal morphology of female internal genitalia, Abno... ORPHA:2138
46,Xy Sex Reversal 7
Sex reversal, Hypoplasia of the fallopian tube, Streak ovary, Abnormal epididymis morphology, Gon... OMIM:233420
Microcephaly 10, Primary, Autosomal Recessive
Cerebellar hemisphere hypoplasia, Cerebellar atrophy, Gliosis OMIM:615095
Developmental And Epileptic Encephalopathy 14
Gliosis OMIM:614959
Congenital Neuronal Ceroid Lipofuscinosis
Cerebellar hypoplasia, Abnormal astrocyte morphology, Cerebellar atrophy, Gliosis ORPHA:168486
Frontotemporal Dementia And/Or Amyotrophic Lateral Sclerosis 1
Abnormal lower motor neuron morphology, Gliosis, Amyotrophic lateral sclerosis OMIM:105550
Spinocerebellar Ataxia, Autosomal Recessive 27
Cerebellar atrophy, Gliosis OMIM:618369
Ovarian Dysgenesis 2
Hypoplasia of the uterus, Streak ovary, Hypergonadotropic hypogonadism OMIM:300510
Hemimegalencephaly
Abnormal neuron morphology, Gliosis ORPHA:99802
Neuropathy, Hereditary Motor And Sensory, Okinawa Type
Gliosis, Degeneration of anterior horn cells OMIM:604484
Mayer-Rokitansky-Kuster-Hauser Syndrome
Hematocolpos, Abnormal female external genitalia morphology, Aplasia of the vagina, Polycystic ov... OMIM:277000
Hereditary Breast And/Or Ovarian Cancer Syndrome
Abnormal fallopian tube morphology, Ovarian neoplasm, Prostate cancer ORPHA:145
Testicular Agenesis
Absent external genitalia, Hypoplasia of the uterus, Vanishing testis, Ambiguous genitalia, Uroge... ORPHA:325124
Mitochondrial Complex Iv Deficiency, Nuclear Type 6
Gliosis OMIM:615119
Pick Disease Of Brain
Gliosis OMIM:172700
Leydig Cell Hypoplasia
Male hypogonadism, Hypoplasia of the Leydig cells, Abnormal external genitalia, Cryptorchidism, T... ORPHA:755
Premature Ovarian Failure 7
Clitoral hypertrophy, Hypoplasia of the uterus, Gonadal dysgenesis OMIM:612964
Encephalopathy, Familial, With Neuroserpin Inclusion Bodies
Gliosis OMIM:604218
Premature Ovarian Failure 13
Hypoplasia of the uterus OMIM:617442
Diethylstilbestrol Syndrome
Hypoplasia of the uterus, Abnormality of the uterus, Vaginal neoplasm, Cryptorchidism, Testicular... ORPHA:1916
Hypomelia With Mullerian Duct Anomalies
Uterus didelphys, Longitudinal vaginal septum OMIM:146160
Mullerian Aplasia And Hyperandrogenism
Aplasia of the uterus, Abnormal external genitalia, Aplasia of the fallopian tube, Aplasia of the... OMIM:158330
Perrault Syndrome 6
Hypoplasia of the uterus, Streak ovary OMIM:617565
Spinocerebellar Ataxia 17
Cerebellar atrophy, Gliosis OMIM:607136
Adducted Thumbs Syndrome
Myelin-dependent gliosis OMIM:201550
46,Xy Gonadal Dysgenesis-Motor And Sensory Neuropathy Syndrome
Male hypogonadism, Abnormal vagina morphology, Gonadal dysgenesis, Abnormal female external genit... ORPHA:168563
Primary Non-Essential Cutis Verticis Gyrata
Gliosis ORPHA:357225
L-2-Hydroxyglutaric Aciduria
Cerebellar atrophy, Gliosis OMIM:236792
Intellectual Developmental Disorder, X-Linked 12
Cerebellar vermis hypoplasia, Abnormal cerebellum morphology, Gliosis OMIM:300957
Hydatidiform Mole
Enlarged uterus ORPHA:99927
Spastic Paraplegia 50, Autosomal Recessive
Cerebellar atrophy, Gliosis OMIM:612936
Frontotemporal Dementia With Motor Neuron Disease
Abnormal lower motor neuron morphology, Abnormal upper motor neuron morphology, Gliosis ORPHA:275872
Ovarian Dysgenesis 7
Hypoplasia of the uterus OMIM:618117
Vaginal Atresia
Imperforate hymen, Uterus didelphys, Abnormality of the uterus, Vaginal hematocele, Transverse va... ORPHA:65681
Leukoencephalopathy, Hereditary Diffuse, With Spheroids 1
Gliosis OMIM:221820
Wilms Tumor, Aniridia, Genitourinary Anomalies, And Impaired Intellectual Development Syndrome
Abnormal vagina morphology, Abnormality of the uterus, Streak ovary, Cryptorchidism, Gonadoblasto... OMIM:194072
Hypogonadotropic Hypogonadism 12 With Or Without Anosmia
Decreased testicular size, Cryptorchidism, Hypogonadotropic hypogonadism, Hypoplasia of the ovary... OMIM:614841
Pyruvate Dehydrogenase E1-Alpha Deficiency
Cerebellar gliosis, Cerebellar cyst, Gliosis, Basal ganglia gliosis ORPHA:79243
Complete Androgen Insensitivity Syndrome
Abnormal morphology of female internal genitalia, Bilateral cryptorchidism, Aplasia of the uterus... ORPHA:99429
X-Linked Intellectual Disability-Short Stature-Overweight Syndrome
Cerebellar dysplasia, Gliosis ORPHA:457240
Hypogonadotropic Hypogonadism 13 With Or Without Anosmia
Hypogonadotropic hypogonadism, Hypoplasia of the uterus OMIM:614842
Polycystic Lipomembranous Osteodysplasia With Sclerosing Leukoencephalopathy 1
Abnormal upper motor neuron morphology, Gliosis OMIM:221770
Ovarian Dysgenesis 5
Hypoplasia of the uterus OMIM:617690
Partial Androgen Insensitivity Syndrome
Clitoral hypertrophy, Bifid scrotum, Bilateral cryptorchidism, Azoospermia, Aplasia of the ovary,... ORPHA:90797
Perrault Syndrome 3
Hypoplasia of the uterus, Streak ovary, Hypergonadotropic hypogonadism OMIM:614129
Leukoencephalopathy With Vanishing White Matter 1
Gliosis OMIM:603896
Encephalopathy, Acute, Infection-Induced, Susceptibility To, 3
Gliosis OMIM:608033
Sporadic Creutzfeldt-Jakob Disease
Astrocytosis, Gliosis ORPHA:204
Cerebrooculofacioskeletal Syndrome 1
Cerebellar hypoplasia, Cerebellar atrophy, Gliosis OMIM:214150
Leukodystrophy, Demyelinating, Adult-Onset, Autosomal Dominant
Abnormal cerebellum morphology, Gliosis OMIM:169500
Hypogonadotropic Hypogonadism 8 With Or Without Anosmia
Decreased testicular size, Azoospermia, Cryptorchidism, Hypogonadotropic hypogonadism, Micropenis... OMIM:614837
Renal And Mullerian Duct Hypoplasia
Aplasia of the uterus, Anteriorly displaced urethral meatus, Hydrocele testis OMIM:266810
Pontocerebellar Hypoplasia, Type 2A
Cerebellar hypoplasia, Gliosis, Hypoplasia of the pons OMIM:277470
Premature Ovarian Failure 6
Hypoplasia of the uterus, Streak ovary OMIM:612310
Premature Ovarian Failure 18
Hypoplasia of the uterus, Hypoplasia of the ovary OMIM:619203
Huntington Disease-Like 1
Cerebellar atrophy, Gliosis ORPHA:157941
Mitochondrial Complex Iv Deficiency, Nuclear Type 2
Gliosis, Cerebellar atrophy, Basal ganglia gliosis OMIM:604377
Spongiform Encephalopathy With Neuropsychiatric Features
Gliosis OMIM:606688
Neurodegeneration With Brain Iron Accumulation 2A
Cerebellar atrophy, Gliosis OMIM:256600
Leigh Syndrome, Nuclear
Gliosis OMIM:256000
Ovarian Dysgenesis 9
Hypoplasia of the uterus, Hypoplasia of the ovary OMIM:619665
Early-Onset Progressive Leukoencephalopathy-Central Nervous System Calcification-Deafness-Visual Impairment Syndrome
Cerebellar hypoplasia, Gliosis ORPHA:3240
Combined Oxidative Phosphorylation Deficiency 24
Cerebellar atrophy, Gliosis OMIM:616239
Lissencephaly, X-Linked, 2
Gliosis OMIM:300215
46,Xx Sex Reversal 2
Small scrotum, Bifid scrotum, Non-obstructive azoospermia, Azoospermia, True hermaphroditism, Ovo... OMIM:278850
Machado-Joseph Disease
Dilated fourth ventricle, Cerebellar atrophy, Gliosis OMIM:109150
Combined Oxidative Phosphorylation Deficiency 14
Gliosis, Cerebellar atrophy, Basal ganglia gliosis OMIM:614946
Rigidity And Multifocal Seizure Syndrome, Lethal Neonatal
Gliosis OMIM:614498
Pelizaeus-Merzbacher Disease, Connatal Form
Cerebellar hypoplasia, Gliosis ORPHA:280210
Mullerian Duct Aplasia, Unilateral Renal Agenesis, And Cervicothoracic Somite Anomalies
Azoospermia, Hypoplasia of the uterus, Bicornuate uterus OMIM:601076
Lumbar Syndrome
Bifid scrotum, Cryptorchidism, Hypoplastic labia majora, Ambiguous genitalia, Micropenis, Bifid u... ORPHA:83628
Kleefstra Syndrome Due To A Point Mutation
Cerebellar hypoplasia, Gliosis ORPHA:261652
Satoyoshi Syndrome
Abnormality of the ovary, Hypoplasia of the uterus, Hypoplasia of the ovary, Abnormality of the u... ORPHA:3130
Townes-Brocks Syndrome 2
Bifid uterus, Rectovaginal fistula, Hypospadias OMIM:617466
Lethal Omphalocele-Cleft Palate Syndrome
Bifid uterus ORPHA:2736
Familial Acute Necrotizing Encephalopathy
Gliosis ORPHA:88619
Encephalopathy, Progressive, Early-Onset, With Brain Atrophy And Thin Corpus Callosum
Cerebellar atrophy, Gliosis OMIM:617193
Mayer-Rokitansky-Küster-Hauser Syndrome
Ectopic ovary, Aplasia of the ovary, Endometriosis, Aplasia of the uterus, Hypoplasia of the vagina ORPHA:3109
Perrault Syndrome 4
Hypoplasia of the uterus, Hypoplasia of the ovary, Bicornuate uterus OMIM:615300
Neurodegeneration, Childhood-Onset, With Progressive Microcephaly
Gliosis OMIM:619847
Mannosidosis, Alpha B, Lysosomal
Cerebellar atrophy, Gliosis OMIM:248500
Combined Oxidative Phosphorylation Deficiency 58
Cerebellar atrophy, Gliosis OMIM:620451
Hypoparathyroidism, Sensorineural Deafness, And Renal Dysplasia Syndrome
Aplasia of the uterus, Septate vagina, Uterus didelphys, Aplasia of the vagina OMIM:146255
Congenital Adrenal Hyperplasia Due To 17-Alpha-Hydroxylase Deficiency
Male hypogonadism, Precocious puberty in females, Bifid scrotum, Bilateral cryptorchidism, Ovaria... ORPHA:90793
Müllerian Aplasia And Hyperandrogenism
Abnormality of the ovary, Hypoplasia of the uterus, Abnormal vagina morphology ORPHA:247768
Leigh Syndrome
Abnormal dentate nucleus morphology, Cerebellar atrophy, Gliosis, Olivopontocerebellar atrophy ORPHA:506
Adrenal Hyperplasia, Congenital, Due To Steroid 11-Beta-Hydroxylase Deficiency
Clitoral hypertrophy, Long penis, Precocious puberty in males, Decreased testicular size, Ambiguo... OMIM:202010
46,Xy Sex Reversal 4
Gonadal dysgenesis, Hypoplastic labia majora, Hypoplasia of the uterus, Agonadism, Hypergonadotro... OMIM:154230
Multiple Acyl-Coa Dehydrogenase Deficiency
Gliosis ORPHA:26791
Progressive Supranuclear Palsy
Gliosis ORPHA:683
Multiple Acyl-Coa Dehydrogenase Deficiency
Gliosis OMIM:231680
Amed Syndrome, Digenic
Hypoplasia of the uterus OMIM:619151
Papillorenal Syndrome
Chiari type I malformation, Gliosis OMIM:120330
Frontotemporal Lobar Degeneration With Tdp43 Inclusions, Grn-Related
Gliosis OMIM:607485
Satoyoshi Syndrome
Hypoplasia of the uterus OMIM:600705
Seckel Syndrome 7
Hypoplasia of the uterus OMIM:614851
Tay-Sachs Disease
Cerebellar atrophy, Gliosis ORPHA:845
46,Xy Difference Of Sex Development-Adrenal Insufficiency Due To Cyp11A1 Deficiency
Midshaft hypospadias, Clitoral hypertrophy, Abnormality of the Leydig cells, Abnormal vagina morp... ORPHA:168558
Estrogen Resistance
Hypoplasia of the uterus, Polycystic ovaries OMIM:615363
Normosmic Congenital Hypogonadotropic Hypogonadism
Male hypogonadism, Non-obstructive azoospermia, Decreased testicular size, Azoospermia, Cryptorch... ORPHA:432
Inherited Isolated Adrenal Insufficiency Due To Partial Cyp11A1 Deficiency
Midshaft hypospadias, Clitoral hypertrophy, Abnormality of the Leydig cells, Abnormal vagina morp... ORPHA:289548
Encephalopathy, Progressive, Early-Onset, With Brain Edema And/Or Leukoencephalopathy, 2
Gliosis OMIM:618321
Parkinson Disease 1, Autosomal Dominant
Gliosis OMIM:168601
D-Bifunctional Protein Deficiency
Cerebellar atrophy, Gliosis OMIM:261515
Popliteal Pterygium Syndrome
Small scrotum, Bifid scrotum, Cryptorchidism, Hypoplastic labia majora, Hypoplasia of the uterus,... OMIM:119500
Neurodevelopmental Disorder With Epilepsy And Hemochromatosis
Cerebellar atrophy, Gliosis OMIM:301072
Cerebrotendinous Xanthomatosis
Cerebellar atrophy, Abnormal cerebellum morphology, Abnormal dentate nucleus morphology, Gliosis,... ORPHA:909
Mitochondrial Dna Depletion Syndrome 4A (Alpers Type)
Astrocytosis, Cerebellar atrophy, Gliosis OMIM:203700
Meckel Syndrome 12
Vaginal atresia, Hypoplasia of the uterus OMIM:616258
46,Xy Difference Of Sex Development Due To Isolated 17,20-Lyase Deficiency
Decreased testicular size, Cryptorchidism, Polycystic ovaries, Enlarged polycystic ovaries, Ambig... ORPHA:90796
Microcephaly 20, Primary, Autosomal Recessive
Vaginal atresia, Hypoplasia of the uterus OMIM:617914
Hypoparathyroidism-Sensorineural Deafness-Renal Disease Syndrome
Vaginal atresia, Aplasia of the uterus, Septate vagina, Uterus didelphys ORPHA:2237
Mitochondrial Complex I Deficiency, Nuclear Type 2
Gliosis OMIM:618222
Oeis Complex
Ambiguous genitalia, female, Absent scrotum, Cryptorchidism, Ambiguous genitalia, male, Bifid ute... OMIM:258040
Molybdenum Cofactor Deficiency, Type B
Gliosis OMIM:252160
Molybdenum Cofactor Deficiency, Type A
Gliosis OMIM:252150
Hereditary Late-Onset Parkinson Disease
Gliosis ORPHA:411602
Alacrimia-Choreoathetosis-Liver Dysfunction Syndrome
Cerebellar atrophy, Gliosis ORPHA:404454
Multiple Congenital Anomalies-Hypotonia-Seizures Syndrome 2
Cerebellar hypoplasia, Abnormal pons morphology, Gliosis OMIM:300868
Estrogen Resistance Syndrome
Enlarged polycystic ovaries, Hypoplasia of the uterus ORPHA:785
Neurodevelopmental Disorder With Intracranial Hemorrhage, Seizures, And Spasticity
Gliosis OMIM:620371
Spondylocostal Dysostosis With Anal Atresia And Urogenital Anomalies
Aplasia of the uterus, Absent external genitalia, Aplasia of the vagina OMIM:271520
Pontocerebellar Hypoplasia Type 7
Clitoral hypertrophy, Microphallus, Gonadal dysgenesis, Cryptorchidism, Aplasia of the uterus, Am... ORPHA:284339
Cockayne Syndrome
Cerebellar dentate nucleus calcification, Cerebellar atrophy, Gliosis ORPHA:191
Congenital Disorder Of Deglycosylation 1
Gliosis OMIM:615273
Meckel Syndrome 14
Aplasia of the uterus, Ambiguous genitalia OMIM:619879
Classic Congenital Adrenal Hyperplasia Due To 21-Hydroxylase Deficiency
Clitoral hypertrophy, Long penis, Precocious puberty in females, Decreased testicular size, Ambig... ORPHA:90794
Supranuclear Palsy, Progressive, 1
Astrocytosis, Gliosis OMIM:601104
Thrombocytopenia-Absent Radius Syndrome
Aplasia of the uterus ORPHA:3320
Helsmoortel-Van Der Aa Syndrome
Gliosis OMIM:615873
Mitochondrial Complex Iii Deficiency, Nuclear Type 1
Cerebellar atrophy, Gliosis OMIM:124000
Acromesomelic Dysplasia 3
Hypoplasia of the uterus, Hypergonadotropic hypogonadism OMIM:609441
Neurodevelopmental Disorder With Hypotonia And Speech Delay, With Or Without Seizures
Cerebellar vermis hypoplasia, Gliosis, Hypoplasia of the pons OMIM:620455
Dyrk1A-Related Intellectual Disability Syndrome Due To 21Q22.13Q22.2 Microdeletion
Gliosis ORPHA:268261
Craniofrontonasal Dysplasia-Poland Anomaly Syndrome
Abnormal reproductive system morphology, Bifid uterus ORPHA:1521
Supranuclear Palsy, Progressive, 2
Gliosis OMIM:609454
Woodhouse-Sakati Syndrome
Decreased testicular size, Hypogonadotropic hypogonadism, Micropenis, Hypoplasia of the uterus, H... OMIM:241080
Phocomelia, Schinzel Type
Aplasia of the uterus, Hypoplasia of penis, Cryptorchidism ORPHA:2879
Chromosome 17Q12 Deletion Syndrome
Cryptorchidism, Ovarian cyst, Aplasia of the vagina, Aplasia of the uterus, Unicornuate uterus OMIM:614527
Cutis Laxa, Autosomal Recessive, Type Iid
Gliosis OMIM:617403
Diets-Jongmans Syndrome
Gliosis OMIM:618846
Intellectual Developmental Disorder With Microcephaly And With Or Without Ocular Malformations Or Hypogonadotropic Hypogonadism
Hypoplasia of the uterus OMIM:615866
Microcephaly-Corpus Callosum Hypoplasia-Intellectual Disability-Facial Dysmorphism Syndrome
Aplasia of the uterus, Aplasia of the vagina ORPHA:457284
Woodhouse-Sakati Syndrome
Hypogonadism, Decreased testicular size, Streak ovary, Abnormal spermatogenesis, Micropenis, Hypo... ORPHA:3464
Linear Skin Defects With Multiple Congenital Anomalies 1
Clitoral hypertrophy, Ovotestis, Chordee, Micropenis, Hypoplasia of the uterus, Hypospadias OMIM:309801
Fanconi Anemia, Complementation Group L
Micropenis, Aplasia of the uterus OMIM:614083
Mitochondrial Complex Iv Deficiency, Nuclear Type 5
Cerebellar vermis hypoplasia, Gliosis OMIM:220111
Gabriele-De Vries Syndrome
Gliosis ORPHA:506358
Cardiac-Urogenital Syndrome
Bifid scrotum, Cryptorchidism, Aplasia of the uterus, Ambiguous genitalia, Penoscrotal hypospadia... OMIM:618280
Exstrophy-Epispadias Complex
Penoscrotal transposition, Bifid scrotum, Cystocele, Cryptorchidism, Bifid penis, Bifid uterus, A... ORPHA:322
Microphthalmia, Syndromic 9
Hypoplasia of the uterus, Bicornuate uterus, Cryptorchidism OMIM:601186
Limb-Mammary Syndrome
Aplasia of the uterus, Aplasia of the ovary ORPHA:69085
Myoectodermal Gonadal Dysgenesis Syndrome
Hypoplastic labia majora, Hypoplasia of the uterus, Clitoral hypoplasia, Gonadal dysgenesis OMIM:618419
Blepharophimosis, Ptosis, And Epicanthus Inversus
Hypoplasia of the uterus OMIM:110100
Renal Cysts And Diabetes Syndrome
Atretic vas deferens, Epididymal cyst, Hypoplasia of the uterus, Bicornuate uterus, Hypospadias OMIM:137920
Thrombocytopenia-Absent Radius Syndrome
Aplasia of the uterus OMIM:274000
Antley-Bixler Syndrome With Genital Anomalies And Disordered Steroidogenesis
Small scrotum, Clitoral hypertrophy, Vesicovaginal fistula, Bifid scrotum, Cryptorchidism, Ovaria... OMIM:201750
Ehlers-Danlos Syndrome, Vascular Type
Uterine rupture, Cystocele, Cryptorchidism, Uterine prolapse, Cervical insufficiency OMIM:130050
Hydrolethalus Syndrome 1
Bifid uterus, Hypospadias, Abnormal vagina morphology OMIM:236680
Wolf-Hirschhorn Syndrome
Precocious puberty, Aplasia of the uterus, Hypospadias, Cryptorchidism OMIM:194190
Coffin-Siris Syndrome 1
Aplasia of the uterus, Clitoral hypertrophy, Hypospadias, Cryptorchidism OMIM:135900
Blepharophimosis-Ptosis-Epicanthus Inversus Syndrome Plus
Hypoplasia of the uterus, Streak ovary, Hypergonadotropic hypogonadism, Polycystic ovaries ORPHA:572333
Loeys-Dietz Syndrome
Uterine rupture ORPHA:60030
Ulna And Fibula, Absence Of, With Severe Limb Deficiency
Small scrotum, Cryptorchidism, Aplasia of the uterus, Anteriorly displaced genitalia, Hypospadias OMIM:276820
Townes-Brocks Syndrome 1
Bifid scrotum, Cryptorchidism, Rectoperineal fistula, Bifid uterus, Rectovaginal fistula, Hypospa... OMIM:107480
Neu-Laxova Syndrome 1
Bifid uterus, Cryptorchidism OMIM:256520
Okamoto Syndrome
Bifid uterus ORPHA:2729
Norrie Disease
Uterine rupture, Cryptorchidism ORPHA:649
Vascular Ehlers-Danlos Syndrome
Uterine rupture, Cystocele, Cryptorchidism, Uterine prolapse, Hypospadias ORPHA:286
Peters Plus Syndrome
Hypoplasia of the uterus, Hypospadias, Cryptorchidism, Clitoral hypoplasia ORPHA:709
Pallister-Killian Syndrome
Small scrotum, Cryptorchidism, Aplasia of the uterus, Hypoplastic labia majora, Aplasia of the up... OMIM:601803
Peters-Plus Syndrome
Cryptorchidism, Hypoplastic labia majora, Hypoplasia of the vagina, Hypoplasia of the uterus, Hyp... OMIM:261540

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Sparcl1

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Sparcl1.

No publications found that use IMPC mice or data for Sparcl1.

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MGI Allele Allele Type Produced
Sparcl1tm96918(L1L2_Bact_P) KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors
Sparcl1em1(IMPC)Mbp Exon Deletion Mice, Tissue

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