Genes Phenotypes

Gene: Nptn

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Name
neuroplastin
MGI ID
MGI:108077
Synonyms
Sdfr1
Viability
Homozygous - Viable
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (20) Measurements chart (242) All data table (540)
Expression & images (67) Disease models (0) Order (2)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal behavior Nptntm1b(EUCOMM)Hmgu HOM Early adult 7.65×10-10
limb grasping Nptntm1b(EUCOMM)Hmgu HOM Early adult 3.19×10-05
abnormal ear morphology Nptntm1b(EUCOMM)Hmgu HOM Early adult 5.79×10-24
abnormal gait Nptntm1b(EUCOMM)Hmgu HOM Early adult 1.40×10-09
increased lean body mass Nptntm1b(EUCOMM)Hmgu HOM Early adult 9.81×10-05
increased circulating iron level Nptntm1b(EUCOMM)Hmgu HOM Early adult 1.51×10-05
increased hemoglobin content Nptntm1b(EUCOMM)Hmgu HOM Early adult 1.87×10-05
increased or absent threshold for auditory brainstem response Nptntm1b(EUCOMM)Hmgu HOM Early adult 2.00×10-06
decreased prepulse inhibition Nptntm1b(EUCOMM)Hmgu HOM Early adult 7.51×10-18
decreased total body fat amount Nptntm1b(EUCOMM)Hmgu HOM Early adult 1.36×10-08
increased mean corpuscular volume Nptntm1b(EUCOMM)Hmgu HOM Early adult 8.19×10-06
abnormal iris morphology Nptntm1b(EUCOMM)Hmgu HOM Early adult 6.13×10-05
increased circulating phosphate level Nptntm1b(EUCOMM)Hmgu HOM Early adult 1.44×10-06
hyperactivity Nptntm1b(EUCOMM)Hmgu HOM Early adult 6.65×10-08
tremors Nptntm1b(EUCOMM)Hmgu HOM Early adult 3.20×10-06
decreased startle reflex Nptntm1b(EUCOMM)Hmgu HOM Early adult 5.68×10-06
increased bone mineral content Nptntm1b(EUCOMM)Hmgu HOM Early adult 5.62×10-06
decreased lean body mass Nptntm1b(EUCOMM)Hmgu HOM Early adult 3.86×10-06
abnormal startle reflex Nptntm1b(EUCOMM)Hmgu HOM Early adult 8.34×10-07
increased circulating cholesterol level Nptntm1b(EUCOMM)Hmgu HOM Early adult 6.84×10-05

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 4 No  (2/584)  (4/4)  Wholemount images
Aorta 4 No  (4/4)  Wholemount images
Bone 4 No  (4/4)  Wholemount images
Brain 4 No  (4/4)  Wholemount images
Brainstem 4 No N/A
Brown adipose tissue 4 No N/A
Cartilage tissue 4 No  (4/4)  Wholemount images
Cerebellum 4 No  (4/4)  Wholemount images
Cerebral cortex 4 No  (4/4)  Wholemount images
Esophagus 4 No  (7/415)  (2/4)  Wholemount images
Eye 4 No  (2/4)  Wholemount images
Gall bladder 4 No  (2/4)  Wholemount images
Heart 4 No  (4/4)  Wholemount images
Hippocampus 4 No N/A
Hypothalamus 4 No N/A
Kidney 4 No  (18/584)  (4/4)  Wholemount images
Large intestine 4 No  (10/584)  (4/4)  Wholemount images
Liver 4 No N/A
Lower urinary tract 4 No  (4/4)  Wholemount images
Lung 4 No  (2/4)  Wholemount images
Lymph node 4 No N/A
Mammary gland 4 No N/A
Olfactory lobe 4 No N/A
Oral epithelium 4 No N/A
Ovary 4 No  (1/584) N/A
Oviduct 4 No  (1/4)  Wholemount images
Pancreas 4 No  (5/584) N/A
Parathyroid gland 4 No N/A
Peripheral nervous system 4 No  (4/4)  Wholemount images
Peyer's patch 4 No N/A
Pituitary gland 4 No N/A
Prostate gland 4 No  (12/584) N/A
Skeletal muscle 4 No N/A
Skin 4 No  (2/4)  Wholemount images
Small intestine 4 No  (9/584)  (3/4)  Wholemount images
Spinal cord 4 No  (3/4)  Wholemount images
Spleen 4 No  (2/584) N/A
Stomach 4 No  (12/584)  (4/4)  Wholemount images
Striatum 4 No  (1/4)  Wholemount images
Testis 4 No  (2/584)  (3/4)  Wholemount images
Thymus 4 No N/A
Thyroid gland 4 No  (15/584) N/A
Trachea 4 No  (4/4)  Wholemount images
Uterus 4 No  (1/4)  Wholemount images
Vascular system 4 No  (4/4)  Wholemount images
White adipose tissue 4 No N/A
LacZ Wholemount Images
Unassigned Top Level MA (1)
cardiovascular system (2)
Heart expression
Aorta expression
MA:0000072
MA:0000062
digestive system (5)
Gall Bladder expression
MA:0000356
endocrine system (1)
Adrenal gland expression
MA:0000116
integumental system (1)
Skin ambiguous
MA:0000151
musculoskeletal system (1)
Cartilage tissue expression
Bone expression
MA:0000104
MA:0001459
nervous system (5)
Cerebral Cortex expression
Cerebellum expression
Brain expression
MA:0000185
MA:0000198
MA:0000168
postnatal mouse (22)
Adrenal gland expression
MA:0000116
reproductive system (2)
Oviduct expression
Uterus expression
MA:0000385
MA:0000389
respiratory system (2)
Lung expression
MA:0000415
sensory organ (1)
Eye expression
MA:0000261
set of connective tissues (2)
Cartilage tissue expression
Bone expression
MA:0000104
MA:0001459
trunk (13)
Adrenal gland expression
MA:0000116
urinary system (2)
Kidney expression
MA:0000368
LacZ Section Images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/504)  (2/4) N/A
Ear 2  (1/504) N/A
Embryo 2  (1/505)  (4/4) N/A
Eye 2  (1/504)  (3/4) N/A
Foot 2  (1/504)  (1/4) N/A
Forebrain 2  (1/504)  (2/4) N/A
Forelimb 2  (1/504) N/A
Hand 2  (1/503)  (1/4) N/A
Head 2  (5/504)  (3/4) N/A
Heart 2  (1/504)  (2/4) N/A
Hindbrain 2  (6/504)  (1/4) N/A
Hindlimb 2  (1/503) N/A
Liver 2  (1/504)  (1/4) N/A
Lung 2  (1/500) N/A
Mandibular process 2  (1/504) N/A
Maxillary process 2  (1/504) N/A
Midbrain 2  (1/504) N/A
Oral cavity 2  (1/504) N/A
Skin 2  (1/504) N/A
Tail 2  (1/504)  (1/4) N/A
Tail somite 2  (1/504) N/A

 Associated Images

Echo: M-Mode Images
64 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
13 Images
X-ray: XRay Images Whole Body Lateral Orientation
13 Images
X-ray: XRay Images Whole Body Dorso Ventral
13 Images
Adult LacZ: LacZ Images Wholemount
23 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
4 Images
Embryo LacZ: LacZ images wholemount
8 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Nptntm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Nptntm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice

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