Genes Phenotypes

Gene: Nptn

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Name
neuroplastin
MGI ID
MGI:108077
Synonyms
Sdfr1
Viability
Homozygous - Viable
View
N/A
Other links
MGI   Ensembl  
Significant phenotypes (19) Measurements chart (243) All data table (535)
Expression & images (67) Disease models (0) Order (2)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal gait Nptntm1b(EUCOMM)Hmgu HOM postnatal 1.58×10-09
decreased startle reflex Nptntm1b(EUCOMM)Hmgu HOM postnatal 5.68×10-06
absent startle reflex Nptntm1b(EUCOMM)Hmgu HOM postnatal 7.55×10-07
abnormal iris morphology Nptntm1b(EUCOMM)Hmgu HOM postnatal 7.34×10-05
hyperactivity Nptntm1b(EUCOMM)Hmgu HOM postnatal 1.69×10-07
increased hemoglobin content Nptntm1b(EUCOMM)Hmgu HOM postnatal 1.80×10-05
decreased total body fat amount Nptntm1b(EUCOMM)Hmgu HOM postnatal 1.33×10-08
increased circulating phosphate level Nptntm1b(EUCOMM)Hmgu HOM postnatal 8.08×10-07
limb grasping Nptntm1b(EUCOMM)Hmgu HOM postnatal 4.08×10-05
increased bone mineral content Nptntm1b(EUCOMM)Hmgu HOM postnatal 5.64×10-06
increased mean corpuscular volume Nptntm1b(EUCOMM)Hmgu HOM postnatal 8.00×10-06
abnormal ear morphology Nptntm1b(EUCOMM)Hmgu HOM postnatal 1.29×10-23
tremors Nptntm1b(EUCOMM)Hmgu HOM postnatal 2.67×10-06
abnormal behavior Nptntm1b(EUCOMM)Hmgu HOM postnatal 6.16×10-10
decreased prepulse inhibition Nptntm1b(EUCOMM)Hmgu HOM postnatal 7.51×10-18
increased or absent threshold for auditory brainstem response Nptntm1b(EUCOMM)Hmgu HOM postnatal 2.00×10-06
increased circulating iron level Nptntm1b(EUCOMM)Hmgu HOM postnatal 1.23×10-05
increased circulating cholesterol level Nptntm1b(EUCOMM)Hmgu HOM postnatal 5.08×10-05
decreased lean body mass Nptntm1b(EUCOMM)Hmgu HOM postnatal 3.55×10-06

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 4 No  (2/584)  (4/4)  Wholemount images
Aorta 4 No  (4/4)  Wholemount images
Bone 4 No  (4/4)  Wholemount images
Brain 4 No  (4/4)  Wholemount images
Brainstem 4 No N/A
Brown adipose tissue 4 No N/A
Cartilage tissue 4 No  (4/4)  Wholemount images
Cerebellum 4 No  (4/4)  Wholemount images
Cerebral cortex 4 No  (4/4)  Wholemount images
Esophagus 4 No  (7/415)  (2/4)  Wholemount images
Eye 4 No  (2/4)  Wholemount images
Gall bladder 4 No  (2/4)  Wholemount images
Heart 4 No  (4/4)  Wholemount images
Hippocampus 4 No N/A
Hypothalamus 4 No N/A
Kidney 4 No  (18/584)  (4/4)  Wholemount images
Large intestine 4 No  (10/584)  (4/4)  Wholemount images
Liver 4 No N/A
Lower urinary tract 4 No  (4/4)  Wholemount images
Lung 4 No  (2/4)  Wholemount images
Lymph node 4 No N/A
Mammary gland 4 No N/A
Olfactory lobe 4 No N/A
Oral epithelium 4 No N/A
Ovary 4 No  (1/584) N/A
Oviduct 4 No  (1/4)  Wholemount images
Pancreas 4 No  (5/584) N/A
Parathyroid gland 4 No N/A
Peripheral nervous system 4 No  (4/4)  Wholemount images
Peyer's patch 4 No N/A
Pituitary gland 4 No N/A
Prostate gland 4 No  (12/584) N/A
Skeletal muscle 4 No N/A
Skin 4 No  (2/4)  Wholemount images
Small intestine 4 No  (9/584)  (3/4)  Wholemount images
Spinal cord 4 No  (3/4)  Wholemount images
Spleen 4 No  (2/584) N/A
Stomach 4 No  (12/584)  (4/4)  Wholemount images
Striatum 4 No  (1/4)  Wholemount images
Testis 4 No  (2/584)  (3/4)  Wholemount images
Thymus 4 No N/A
Thyroid gland 4 No  (15/584) N/A
Trachea 4 No  (4/4)  Wholemount images
Uterus 4 No  (1/4)  Wholemount images
Vascular system 4 No  (4/4)  Wholemount images
White adipose tissue 4 No N/A
LacZ Wholemount Images
Unassigned Top Level MA (1)
cardiovascular system (2)
Heart expression
Aorta expression
MA:0000072
MA:0000062
digestive system (5)
Gall Bladder expression
MA:0000356
endocrine system (1)
Adrenal gland expression
MA:0000116
integumental system (1)
Skin ambiguous
MA:0000151
musculoskeletal system (1)
Cartilage tissue expression
Bone expression
MA:0000104
MA:0001459
nervous system (5)
Cerebral Cortex expression
Cerebellum expression
Brain expression
MA:0000185
MA:0000198
MA:0000168
postnatal mouse (22)
Adrenal gland expression
MA:0000116
reproductive system (2)
Oviduct expression
Uterus expression
MA:0000385
MA:0000389
respiratory system (2)
Lung expression
MA:0000415
sensory organ (1)
Eye expression
MA:0000261
set of connective tissues (2)
Cartilage tissue expression
Bone expression
MA:0000104
MA:0001459
trunk (13)
Adrenal gland expression
MA:0000116
urinary system (2)
Kidney expression
MA:0000368
LacZ Section Images
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/485)  (2/4) N/A
Ear 2  (1/485) N/A
Embryo 2  (1/485)  (4/4) N/A
Eye 2  (1/485)  (3/4) N/A
Foot 2  (1/485)  (2/4) N/A
Forebrain 2  (1/485)  (2/4) N/A
Forelimb 2  (1/485) N/A
Hand 2  (1/485)  (1/4) N/A
Head 2  (5/485)  (2/4) N/A
Heart 2  (1/485)  (2/4) N/A
Hindbrain 2  (6/485)  (1/4) N/A
Hindlimb 2  (1/485) N/A
Liver 2  (1/485)  (1/4) N/A
Lung 2  (1/485) N/A
Mandibular process 2  (1/485) N/A
Maxillary process 2  (1/485) N/A
Midbrain 2  (1/485) N/A
Oral cavity 2  (1/485) N/A
Skin 2  (1/485) N/A
Tail 2  (1/485)  (1/4) N/A
Tail somite 2  (1/485) N/A

 Associated Images

Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
4 Images
X-ray: XRay Images Dorso Ventral
13 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
13 Images
Echo: M-Mode Images
64 Images
X-ray: XRay Images Lateral Orientation
13 Images
Adult LacZ: LacZ Images Wholemount
23 Images
Embryo LacZ: LacZ images wholemount
8 Images

 Disease Models

No associations by disease annotation and gene orthology found.
Please visit the desktop version to see this section

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Nptntm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Nptntm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice

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