Gene: Nptn

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Phenotype System Allele Zyg Sex Life Stage P Value
increased circulating phosphate level Nptntm1b(EUCOMM)Hmgu HOM   Early adult 4.32×10-05
increased bone mineral content Nptntm1b(EUCOMM)Hmgu HOM Early adult 7.27×10-07
abnormal auditory brainstem response Nptntm1b(EUCOMM)Hmgu HOM   Early adult 1.24×10-06
tremors Nptntm1b(EUCOMM)Hmgu HOM Early adult 1.54×10-06
abnormal ear morphology Nptntm1b(EUCOMM)Hmgu HOM Early adult 3.48×10-24
increased mean corpuscular volume Nptntm1b(EUCOMM)Hmgu HOM Early adult 4.31×10-11
decreased prepulse inhibition Nptntm1b(EUCOMM)Hmgu HOM Early adult 7.03×10-09
increased mean corpuscular hemoglobin Nptntm1b(EUCOMM)Hmgu HOM Early adult 4.10×10-08
decreased total body fat amount Nptntm1b(EUCOMM)Hmgu HOM Early adult 2.65×10-06
limb grasping Nptntm1b(EUCOMM)Hmgu HOM   Early adult 2.70×10-05
increased circulating iron level Nptntm1b(EUCOMM)Hmgu HOM Early adult 1.04×10-08
abnormal behavior Nptntm1b(EUCOMM)Hmgu HOM   Early adult 9.56×10-06
increased heart weight Nptntm1b(EUCOMM)Hmgu HOM   Early adult 6.38×10-06
hypoactivity Nptntm1b(EUCOMM)Hmgu HOM Early adult 1.15×10-10
hyperactivity Nptntm1b(EUCOMM)Hmgu HOM Early adult 2.00×10-08
abnormal startle reflex Nptntm1b(EUCOMM)Hmgu HOM Early adult 4.96×10-07
decreased thigmotaxis Nptntm1b(EUCOMM)Hmgu HOM   Early adult 9.56×10-06
increased circulating cholesterol level Nptntm1b(EUCOMM)Hmgu HOM   Early adult 5.55×10-05
abnormal gait Nptntm1b(EUCOMM)Hmgu HOM Early adult 1.48×10-09
decreased anxiety-related response Nptntm1b(EUCOMM)Hmgu HOM   Early adult 3.51×10-06
decreased startle reflex Nptntm1b(EUCOMM)Hmgu HOM Early adult 1.85×10-05
increased hemoglobin content Nptntm1b(EUCOMM)Hmgu HOM Early adult 6.56×10-06
increased lean body mass Nptntm1b(EUCOMM)Hmgu HOM   Early adult 3.75×10-05

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
4 No  (4/583)  (4/4)  Wholemount images
4 No  (1/583)  (4/4)  Wholemount images
4 No  (4/4)  Wholemount images
4 No  (4/583)  (4/4)  Wholemount images
4 No  (2/583) N/A
4 No N/A
4 No  (1/583)  (4/4)  Wholemount images
4 No  (3/583)  (4/4)  Wholemount images
4 No  (2/583)  (4/4)  Wholemount images
4 No  (7/407)  (2/4)  Wholemount images
4 No  (2/4)  Wholemount images
4 No  (2/4)  Wholemount images
4 No  (2/583)  (4/4)  Wholemount images
4 No  (3/583) N/A
4 No  (2/583) N/A
4 No  (21/583)  (4/4)  Wholemount images
4 No  (10/583)  (4/4)  Wholemount images
4 No N/A
4 No  (1/583)  (4/4)  Wholemount images
4 No  (2/583)  (2/4)  Wholemount images
4 No  (1/583) N/A
4 No N/A
4 No  (2/583) N/A
4 No N/A
4 No  (1/583) N/A
4 No  (1/4)  Wholemount images
4 No  (5/583) N/A
4 No  (1/563) N/A
4 No  (2/583)  (4/4)  Wholemount images
4 No N/A
4 No  (1/583) N/A
4 No  (12/583) N/A
4 No N/A
4 No  (1/583)  (2/4)  Wholemount images
4 No  (9/583)  (3/4)  Wholemount images
4 No  (3/583)  (3/4)  Wholemount images
4 No  (3/583) N/A
4 No  (13/583)  (4/4)  Wholemount images
4 No  (3/583)  (1/4)  Wholemount images
4 No  (6/583)  (3/4)  Wholemount images
4 No  (1/583) N/A
4 No  (17/583) N/A
4 No  (3/583)  (4/4)  Wholemount images
4 No  (1/4)  Wholemount images
4 No  (4/4)  Wholemount images
4 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
2  (6/505)  (2/4) N/A
2  (1/505) N/A
2  (1/506)  (4/4) N/A
2  (1/505)  (3/4) N/A
2  (1/505)  (1/4) N/A
2  (1/505)  (2/4) N/A
2  (1/505) N/A
2  (1/505)  (1/4) N/A
2  (5/505)  (3/4) N/A
2  (1/505)  (2/4) N/A
2  (6/505)  (1/4) N/A
2  (1/505) N/A
2  (1/503)  (1/4) N/A
2  (1/503) N/A
2  (1/505) N/A
2  (1/505) N/A
2  (1/505) N/A
2  (1/503) N/A
2  (1/505) N/A
2  (1/505)  (1/4) N/A
2  (1/505) N/A

 Associated Images

X-ray: XRay Images Whole Body Dorso Ventral
13 Images
Echo: M-Mode Images
64 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
13 Images
X-ray: XRay Images Whole Body Lateral Orientation
13 Images
Adult LacZ: LacZ Images Wholemount
23 Images
Embryo LacZ: LacZ images wholemount
8 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
4 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Histopathology

 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Nptntm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Nptntm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice

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