Gene: Nptn

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Phenotype System Allele Zyg Sex Life Stage P Value
increased circulating cholesterol level Nptntm1b(EUCOMM)Hmgu HOM   Early adult 8.01×10-05
abnormal startle reflex Nptntm1b(EUCOMM)Hmgu HOM Early adult 6.72×10-07
hypoactivity Nptntm1b(EUCOMM)Hmgu HOM Early adult 7.81×10-11
decreased thigmotaxis Nptntm1b(EUCOMM)Hmgu HOM   Early adult 7.00×10-06
decreased anxiety-related response Nptntm1b(EUCOMM)Hmgu HOM   Early adult 1.93×10-06
increased heart weight Nptntm1b(EUCOMM)Hmgu HOM   Early adult 5.47×10-06
decreased startle reflex Nptntm1b(EUCOMM)Hmgu HOM Early adult 6.43×10-06
increased circulating iron level Nptntm1b(EUCOMM)Hmgu HOM Early adult 1.46×10-08
increased hemoglobin content Nptntm1b(EUCOMM)Hmgu HOM Early adult 2.68×10-06
increased lean body mass Nptntm1b(EUCOMM)Hmgu HOM   Early adult 3.76×10-05
decreased prepulse inhibition Nptntm1b(EUCOMM)Hmgu HOM Early adult 6.70×10-09
increased mean corpuscular hemoglobin Nptntm1b(EUCOMM)Hmgu HOM Early adult 6.58×10-08
increased hematocrit Nptntm1b(EUCOMM)Hmgu HOM Early adult 9.23×10-05
hyperactivity Nptntm1b(EUCOMM)Hmgu HOM Early adult 8.99×10-09
abnormal behavior Nptntm1b(EUCOMM)Hmgu HOM   Early adult 7.00×10-06
abnormal ear morphology Nptntm1b(EUCOMM)Hmgu HOM Early adult 3.41×10-24
increased mean corpuscular volume Nptntm1b(EUCOMM)Hmgu HOM Early adult 1.30×10-10
abnormal gait Nptntm1b(EUCOMM)Hmgu HOM Early adult 1.46×10-09
increased circulating phosphate level Nptntm1b(EUCOMM)Hmgu HOM   Early adult 4.78×10-05
decreased pulmonary respiratory rate Nptntm1b(EUCOMM)Hmgu HOM   Early adult 4.94×10-05
abnormal auditory brainstem response Nptntm1b(EUCOMM)Hmgu HOM   Early adult 1.24×10-06
decreased total body fat amount Nptntm1b(EUCOMM)Hmgu HOM Early adult 2.64×10-06
limb grasping Nptntm1b(EUCOMM)Hmgu HOM   Early adult 2.68×10-05
tremors Nptntm1b(EUCOMM)Hmgu HOM Early adult 2.61×10-06
increased bone mineral content Nptntm1b(EUCOMM)Hmgu HOM Early adult 7.28×10-07

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 4 No  (3/590)  (4/4)  Wholemount images
Aorta 4 No  (1/590)  (4/4)  Wholemount images
Bone 4 No  (4/4)  Wholemount images
Brain 4 No  (3/590)  (4/4)  Wholemount images
Brainstem 4 No  (2/590) N/A
Brown adipose tissue 4 No N/A
Cartilage tissue 4 No  (4/4)  Wholemount images
Cerebellum 4 No  (3/590)  (4/4)  Wholemount images
Cerebral cortex 4 No  (2/590)  (4/4)  Wholemount images
Esophagus 4 No  (7/415)  (2/4)  Wholemount images
Eye 4 No  (2/4)  Wholemount images
Gall bladder 4 No  (2/4)  Wholemount images
Heart 4 No  (1/590)  (4/4)  Wholemount images
Hippocampus 4 No  (3/590) N/A
Hypothalamus 4 No  (2/590) N/A
Kidney 4 No  (20/590)  (4/4)  Wholemount images
Large intestine 4 No  (10/590)  (4/4)  Wholemount images
Liver 4 No N/A
Lower urinary tract 4 No  (1/590)  (4/4)  Wholemount images
Lung 4 No  (1/590)  (2/4)  Wholemount images
Lymph node 4 No N/A
Mammary gland 4 No N/A
Olfactory lobe 4 No  (2/590) N/A
Oral epithelium 4 No N/A
Ovary 4 No  (1/590) N/A
Oviduct 4 No  (1/4)  Wholemount images
Pancreas 4 No  (5/590) N/A
Parathyroid gland 4 No N/A
Peripheral nervous system 4 No  (1/590)  (4/4)  Wholemount images
Peyer's patch 4 No N/A
Pituitary gland 4 No  (1/590) N/A
Prostate gland 4 No  (12/590) N/A
Skeletal muscle 4 No N/A
Skin 4 No  (2/4)  Wholemount images
Small intestine 4 No  (9/590)  (3/4)  Wholemount images
Spinal cord 4 No  (2/590)  (3/4)  Wholemount images
Spleen 4 No  (2/590) N/A
Stomach 4 No  (13/590)  (4/4)  Wholemount images
Striatum 4 No  (3/590)  (1/4)  Wholemount images
Testis 4 No  (5/590)  (3/4)  Wholemount images
Thymus 4 No N/A
Thyroid gland 4 No  (16/590) N/A
Trachea 4 No  (2/590)  (4/4)  Wholemount images
Uterus 4 No  (1/4)  Wholemount images
Vascular system 4 No  (4/4)  Wholemount images
White adipose tissue 4 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/506)  (2/4) N/A
Ear 2  (1/506) N/A
Embryo 2  (1/507)  (4/4) N/A
Eye 2  (1/506)  (3/4) N/A
Foot 2  (1/506)  (1/4) N/A
Forebrain 2  (1/506)  (2/4) N/A
Forelimb 2  (1/506) N/A
Hand 2  (1/506)  (1/4) N/A
Head 2  (5/506)  (3/4) N/A
Heart 2  (1/506)  (2/4) N/A
Hindbrain 2  (6/506)  (1/4) N/A
Hindlimb 2  (1/506) N/A
Liver 2  (1/504)  (1/4) N/A
Lung 2  (1/504) N/A
Mandibular process 2  (1/506) N/A
Maxillary process 2  (1/506) N/A
Midbrain 2  (1/506) N/A
Oral cavity 2  (1/504) N/A
Skin 2  (1/506) N/A
Tail 2  (1/506)  (1/4) N/A
Tail somite 2  (1/506) N/A

 Associated Images

Echo: M-Mode Images
64 Images
Adult LacZ: LacZ Images Wholemount
23 Images
X-ray: XRay Images Whole Body Dorso Ventral
13 Images
X-ray: XRay Images Whole Body Lateral Orientation
13 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
13 Images
Embryo LacZ: LacZ images wholemount
8 Images
Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
4 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Histopathology

 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Nptntm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice
Nptntm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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