Name
smoothened, frizzled class receptor
MGI ID
MGI:108075
Synonyms
E130215L21Rik
Viability
Embryo viewer
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
increased heart rate variability Smotm1b(KOMP)Wtsi HET   Early adult 5.79×10-06
embryonic lethality prior to tooth bud stage Smotm1b(KOMP)Wtsi HOM   E12.5 0.00
decreased heart rate Smotm1b(KOMP)Wtsi HET   Early adult 6.69×10-05
abnormal skin morphology Smotm1b(KOMP)Wtsi HET Early adult 0.00
abnormal embryo turning Smotm1b(KOMP)Wtsi HOM E9.5 0.00
abnormal embryo development Smotm1b(KOMP)Wtsi HOM E9.5 0.00
prolonged PR interval Smotm1b(KOMP)Wtsi HET Early adult 8.94×10-05
abnormal pericardium morphology Smotm1b(KOMP)Wtsi HOM E9.5 0.00
preweaning lethality, complete penetrance Smotm1b(KOMP)Wtsi HOM   Early adult 0.00

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Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (4/583) N/A
Aorta 2 No  (1/583)  (2/2) N/A
Bone 2 No  (2/2) N/A
Brain 2 No  (4/583)  (2/2) N/A
Brainstem 2 No  (2/583)  (2/2) N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (1/583)  (2/2) N/A
Cecum 2 No  (12/371) N/A
Cerebellum 2 No  (3/583)  (2/2) N/A
Cerebral cortex 2 No  (2/583) N/A
Esophagus 2 No  (7/407)  (2/2) N/A
Eye 2 No N/A
Gall bladder 2 No  (2/2) N/A
Heart 2 No  (2/583)  (2/2) N/A
Hippocampus 2 No  (3/583) N/A
Hypothalamus 2 No  (2/583) N/A
Kidney 2 No  (21/583)  (2/2) N/A
Large intestine 2 No  (10/583)  (2/2) N/A
Liver 2 No N/A
Lower urinary tract 2 No  (1/583)  (2/2) N/A
Lung 2 No  (2/583) N/A
Lymph node 2 No  (1/583) N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No  (2/583)  (2/2) N/A
Oral epithelium 2 No  (2/2) N/A
Ovary 2 No  (1/583)  (1/2) N/A
Oviduct 2 No  (1/2) N/A
Pancreas 2 No  (5/583) N/A
Parathyroid gland 2 No  (1/563)  (2/2) N/A
Peripheral nervous system 2 No  (2/583)  (2/2) N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/583) N/A
Prostate gland 2 No  (12/583)  (1/2) N/A
Skeletal muscle 2 No N/A
Skin 2 No  (1/583)  (2/2) N/A
Small intestine 2 No  (9/583)  (2/2) N/A
Spinal cord 2 No  (3/583)  (2/2) N/A
Spleen 2 No  (3/583) N/A
Stomach 2 No  (13/583)  (2/2) N/A
Striatum 2 No  (3/583)  (2/2) N/A
Testis 2 No  (6/583)  (1/2) N/A
Thymus 2 No  (1/583) N/A
Thyroid gland 2 No  (17/583)  (2/2) N/A
Trachea 2 No  (3/583)  (2/2) N/A
Trigeminal V nerve 2 No  (2/2) N/A
Uterus 2 No  (1/2) N/A
Vas deferens 2 No  (15/382) N/A
Vascular system 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
2  (1/60)  (2/2) N/A
2  (1/64)  (2/2) N/A
2  (6/505)  (2/2) N/A
2  (1/73)  (2/2) N/A
2  (1/64)  (2/2) N/A
2  (1/60)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/506)  (2/2) N/A
2  (1/71)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/55)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/302)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/61)  (2/2) N/A
2  (1/59)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (5/505)  (2/2) N/A
2  (1/60)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/60)  (2/2) N/A
2  (6/505)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/64)  (2/2) N/A
2  (1/64)  (2/2) N/A
2  (1/58)  (2/2) N/A
2  (1/503)  (2/2) N/A
2  (1/302)  (2/2) N/A
2  (1/503)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/55)  (2/2) N/A
2  (1/55)  (2/2) N/A
2  (1/55)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/60)  (2/2) N/A
2  (1/75)  (2/2) N/A
2  (1/60)  (2/2) N/A
2  (1/503)  (2/2) N/A
2  (1/60)  (2/2) N/A
2  (1/55)  (2/2) N/A
2  (1/55)  (2/2) N/A
2  (1/56)  (2/2) N/A
2  (1/64)  (2/2) N/A
2  (1/57)  (2/2) N/A
2  (1/75)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/72)  (2/2) N/A
2  (1/55)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/505)  (2/2) N/A
2  (1/55)  (2/2) N/A
2  (1/55)  (2/2) N/A
2  (1/59)  (2/2) N/A
2  (1/60)  (2/2) N/A
2  (1/60)  (2/2) N/A
2  (1/60)  (2/2) N/A
2  (1/302)  (2/2) N/A
2  (1/302)  (2/2) N/A
2  (1/59)  (2/2) N/A
2  (1/71)  (2/2) N/A

 Associated Images

X-ray: XRay Images Forepaw
9 Images
X-ray: XRay Images Whole Body Lateral Orientation
9 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
9 Images
X-ray: XRay Images Whole Body Dorso Ventral
9 Images
X-ray: XRay Images Skull Lateral Orientation
9 Images
Embryo LacZ: LacZ images wholemount
4 Images
Immunophenotyping: Panel B FCS file(s)
6 Images
Immunophenotyping: Panel A FCS file(s)
6 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Smotm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Smotm199121(L1L2_Bact_P) Targeting vectors
Smotm1b(KOMP)Wtsi Reporter-tagged deletion allele (post-Cre) Mice, Tissue

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