Smyd5 | SET and MYND domain containing 5
Physiological systems
20 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Growth/size/body region Behavior/neurological Skeleton
17 No significant impact
4 Not tested
Data collections
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:45Adult tissues
0Embryo tissues
increased lean body mass | 1 supporting dataset | Smyd5tm1e(EUCOMM)Wtsi | homozygote | Early adult | 6.04x10-5 | ||
abnormal bone mineralization | 1 supporting dataset | Smyd5tm1e(EUCOMM)Wtsi | homozygote | Early adult | 1.63x10-6 | ||
abnormal gait | 1 supporting dataset | Smyd5tm1e(EUCOMM)Wtsi | homozygote | Early adult | 8.94x10-8 |
| | | | | | | | | |
adrenal gland | heterozygote | n/a | 0% (0/2) | 0.7% (4/570) |
aorta | heterozygote | n/a | n/a | 0.19% (1/533) |
blood vessel | heterozygote | n/a | 0% (0/2) | 0% (0/173) |
bone | heterozygote | n/a | 100% (2/2) | 0% (0/394) |
brain | heterozygote | n/a | 100% (2/2) | 0.86% (5/579) |
brainstem | heterozygote | n/a | n/a | 0.41% (2/490) |
brown adipose tissue | heterozygote | n/a | 0% (0/2) | 0% (0/588) |
cartilage tissue | heterozygote | n/a | 100% (2/2) | 0.22% (1/454) |
cerebellum | heterozygote | n/a | n/a | 0.56% (3/532) |
cerebral cortex | heterozygote | n/a | n/a | 0.41% (2/491) |
External links
No external links available for Smyd5.
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Smyd5tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
Smyd5tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell mouse |