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Atr | ataxia telangiectasia and Rad3 related

Physiological systems

19 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Homeostasis/metabolism Growth/size/body region Nervous system Behavior/neurological Mortality/aging Cardiovascular system

13 No significant impact

5 Not tested

Gene metrics:8Significant phenotypes
4Associated diseases
Expression examined in:49Adult tissues
21Embryo tissues

Phenotypes

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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Human diseases caused by Atr mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.






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Histopathology

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IMPC related publications

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Order Mouse and ES Cells

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