Gene: Lrig1

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Name
leucine-rich repeats and immunoglobulin-like domains 1
MGI ID
MGI:107935
Synonyms
LIG-1 Img
Viability
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
increased bone mineral density Lrig1tm1a(EUCOMM)Wtsi HOM Early adult 5.81×10-05
decreased circulating alkaline phosphatase level Lrig1tm1a(EUCOMM)Wtsi HOM Early adult 1.23×10-05
decreased body weight Lrig1tm1a(EUCOMM)Wtsi HOM Early adult 2.16×10-07
abnormal tail morphology Lrig1tm1a(EUCOMM)Wtsi HOM Early adult 2.22×10-06
abnormal skin condition Lrig1tm1a(EUCOMM)Wtsi HOM Early adult 4.25×10-10

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (4/584) N/A
Aorta 2 No  (1/584) N/A
Blood vessel 2 No N/A
Bone 2 No N/A
Brain 2 No  (4/584)  (2/2) N/A
Brainstem 2 No  (2/584) N/A
Brown adipose tissue 2 No  (1/2) N/A
Cartilage tissue 2 No  (1/584) N/A
Cerebellum 2 No  (3/584) N/A
Cerebral cortex 2 No  (2/584) N/A
Eye 2 No  (2/2) N/A
Gall bladder 2 No  (1/2) N/A
Heart 2 No  (2/584)  (2/2) N/A
Hippocampus 2 No  (3/584) N/A
Hypothalamus 2 No  (2/584) N/A
Kidney 2 No  (21/584) N/A
Large intestine 2 No  (10/584)  (2/2) N/A
Liver 2 No N/A
Lower urinary tract 2 No  (1/584) N/A
Lung 2 No  (2/584)  (2/2) N/A
Lymph node 2 No  (1/584) N/A
Mammary gland 2 No  (2/2) N/A
Esophagus 2 No  (1/2) N/A
Olfactory lobe 2 No  (2/584) N/A
Ovary 2 No  (1/584)  (1/2) N/A
Oviduct 2 No  (1/2) N/A
Pancreas 2 No  (5/584) N/A
Parathyroid gland 2 No  (1/562) N/A
Peripheral nervous system 2 No  (2/584)  (2/2) N/A
Peyer's patch 2 No  (1/176) N/A
Pituitary gland 2 No  (1/584)  (1/2) N/A
Prostate gland 2 No  (12/584) N/A
Skeletal muscle tissue 2 No N/A
Skin 2 No  (1/584)  (2/2) N/A
Small intestine 2 No  (9/584)  (2/2) N/A
Spinal cord 2 No  (3/584)  (2/2) N/A
Spleen 2 No  (3/584) N/A
Stomach 2 No  (12/584)  (2/2) N/A
Striatum 2 No  (3/584) N/A
Testis 2 No  (6/584)  (1/2) N/A
Thymus 2 No  (1/584)  (1/2) N/A
Thyroid gland 2 No  (16/584)  (1/2) N/A
Trachea 2 No  (3/584)  (2/2) N/A
Uterus 2 No  (1/2) N/A
White adipose tissue 2 No  (1/2) N/A
LacZ Section Images

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View all 12 images

No Embryo expression data was found for this gene.

 Associated Images

Histopathology
3 Images
Legacy Phenotype Associated Images

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View all 6 images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Histopathology

Phenotype Allele Zygosity Sex Life Stage
Skin - hyperplasia Lrig1tm1a(EUCOMM)Wtsi HOM Early adult
Skin - MPATH diagnostic term acanthosis Lrig1tm1a(EUCOMM)Wtsi HOM Early adult

 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Lrig1tm42916(L1L2_gt2_Del_LacZ) Targeting vectors
Lrig1tm42916(pL1L2_frt15_BetactinBSD_frt14_neo_Rox) Targeting vectors
Lrig1tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Lrig1tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells

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