Genes Phenotypes

Gene: Rock1

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Name
Rho-associated coiled-coil containing protein kinase 1
MGI ID
MGI:107927
Synonyms
Rock-I 1110055K06Rik
Viability
Subviable
Embryo viewer
3D Imaging
Other links
MGI   Ensembl  
Significant phenotypes (7) Measurements chart (226) All data table (1193)
Expression & images (30) Disease models (0) Order (2)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
preweaning lethality, incomplete penetrance Rock1tm1b(NCOM)Mfgc HOM Early adult 0.00
pallor Rock1tm1b(NCOM)Mfgc HOM E15.5 0.00
decreased mean corpuscular volume Rock1tm1b(NCOM)Mfgc HET Early adult 3.20×10-05
decreased mean platelet volume Rock1tm1b(NCOM)Mfgc HET Early adult 4.13×10-05
abnormal heart morphology Rock1tm1b(NCOM)Mfgc HOM E15.5 0.00
abnormal craniofacial morphology Rock1tm1b(NCOM)Mfgc HET E15.5 0.00
abnormal embryo size Rock1tm1b(NCOM)Mfgc HOM E15.5 0.00

Download data as:  TSV  XLS

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

No Adult expression data was found for this gene.
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
2  (1/65) N/A
5  (6/506)  (2/8) N/A
2  (1/74)  (2/2) N/A
5  (1/506)  (2/8) N/A
5  (1/507)  (2/8) N/A
5  (1/506)  (2/8) N/A
5  (1/506) N/A
5  (1/506)  (2/8) N/A
5  (1/506)  (2/8) N/A
2  (1/60)  (2/2) N/A
5  (1/506) N/A
5  (5/506) N/A
5  (1/506)  (2/8) N/A
5  (6/506)  (2/8) N/A
5  (1/506)  (2/8) N/A
5  (1/504)  (2/8) N/A
5  (1/504) N/A
5  (1/506) N/A
5  (1/506) N/A
5  (1/506)  (2/8) N/A
2  (1/76) N/A
5  (1/504)  (2/8) N/A
2  (7/39)  (2/2) N/A
2  (1/76)  (2/2) N/A
5  (1/506) N/A
2  (1/73)  (2/2) N/A
5  (1/506) N/A
5  (1/506)  (2/8) N/A
2  (1/60) N/A
2  (1/60)  (2/2) N/A

 Associated Images

Gross Pathology and Tissue Collection
10 Images
X-ray: XRay Images Whole Body Dorso Ventral
11 Images
X-ray: XRay Images Whole Body Lateral Orientation
11 Images
Embryo LacZ: LacZ images wholemount
32 Images
Immunophenotyping: Panel A FCS file(s)
2 Images
Immunophenotyping: Panel B FCS file(s)
2 Images
X-ray: XRay Images Skull Lateral Orientation
11 Images
Eye Morphology: Images Ophthalmoscopy
12 Images
Gross Morphology Embryo E14.5-E15.5
4 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
11 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Rock1tm1b(NCOM)Mfgc Reporter-tagged deletion allele (post-Cre) Mice, Tissue
Rock1tm1a(NCOM)Mfgc KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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