Genes Phenotypes

Gene: Rock1

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Name
Rho-associated coiled-coil containing protein kinase 1
MGI ID
MGI:107927
Synonyms
1110055K06Rik Rock-I
Viability
Homozygous - Subviable
View
3D Imaging
Other links
MGI   Ensembl  
Significant phenotypes (3) Measurements chart (309) All data table (805)
Expression & images (30) Disease models (0) Order (2)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
edema Rock1tm1b(NCOM)Mfgc HOM embryonic day 15.5 0.00
preweaning lethality, incomplete penetrance Rock1tm1b(NCOM)Mfgc HOM n/a 0.00
edema Rock1tm1b(NCOM)Mfgc HET embryonic day 15.5 0.00

Download data as:  TSV  XLS

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Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

No Adult expression data was found for this gene.
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 2  (1/51) N/A
Brain 5  (6/485)  (2/8) N/A
Central nervous system ganglion 2  (1/51)  (2/2) N/A
Ear 5  (1/485)  (2/8) N/A
Embryo 5  (1/485)  (2/8) N/A
Eye 5  (1/485)  (2/8) N/A
Foot 5  (1/485) N/A
Forebrain 5  (1/485)  (2/8) N/A
Forelimb 5  (1/485)  (2/8) N/A
Gut 2  (1/50)  (2/2) N/A
Hand 5  (1/485) N/A
Head 5  (5/485) N/A
Heart 5  (1/485)  (2/8) N/A
Hindbrain 5  (6/485)  (2/8) N/A
Hindlimb 5  (1/485)  (2/8) N/A
Liver 5  (1/485)  (2/8) N/A
Lung 5  (1/485) N/A
Mandibular process 5  (1/485) N/A
Maxillary process 5  (1/485) N/A
Midbrain 5  (1/485)  (2/8) N/A
Nose 2  (1/51) N/A
Oral cavity 5  (1/485)  (2/8) N/A
2  (7/25)  (2/2) N/A
Skeleton 2  (1/51)  (2/2) N/A
Skin 5  (1/485) N/A
Spinal cord 2  (1/50)  (2/2) N/A
Tail 5  (1/485) N/A
Tail somite 5  (1/485)  (2/8) N/A
Trachea 2  (1/50) N/A
Urinary system 2  (1/50)  (2/2) N/A

 Associated Images

X-ray: XRay Images Dorso Ventral
11 Images
Gross Pathology and Tissue Collection
10 Images
Eye Morphology: Images Ophthalmoscopy
12 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
11 Images
Gross Morphology Embryo E14.5-E15.5
4 Images
Histopathology
2 Images
X-ray: XRay Images Lateral Orientation
11 Images
X-ray: XRay Images Skull Lateral Orientation
11 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Rock1tm1a(NCOM)Mfgc KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Rock1tm1b(NCOM)Mfgc Reporter-tagged deletion allele (post-Cre) Mice, Tissue

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