Tial1 | Tia1 cytotoxic granule-associated RNA binding protein-like 1
Physiological systems
15 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Homeostasis/metabolism Adipose tissue Growth/size/body region Hematopoietic system Skeleton
10 No significant impact
9 Not tested
Data collections
Gene metrics:8Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
decreased circulating triglyceride level | 1 supporting dataset | Tial1tm1b(EUCOMM)Wtsi | heterozygote | Early adult | 2.15x10-5 | ||
decreased total body fat amount | 2 supporting datasets | Tial1tm1b(EUCOMM)Wtsi | heterozygote | Early adult | 1.53x10-6 | ||
thrombocytosis | 1 supporting dataset | Tial1tm1b(EUCOMM)Wtsi | heterozygote | Early adult | 1.54x10-5 | ||
increased bone mineral density | 1 supporting dataset | Tial1tm1b(EUCOMM)Wtsi | heterozygote | Early adult | 3.55x10-6 | ||
decreased circulating cholesterol level | 1 supporting dataset | Tial1tm1b(EUCOMM)Wtsi | heterozygote | Early adult | 8.44x10-9 | ||
decreased circulating HDL cholesterol level | 1 supporting dataset | Tial1tm1b(EUCOMM)Wtsi | heterozygote | Early adult | 9.18x10-8 | ||
increased lean body mass | 2 supporting datasets | Tial1tm1b(EUCOMM)Wtsi | heterozygote | Early adult | 2.35x10-6 | ||
decreased circulating calcium level | 1 supporting dataset | Tial1tm1b(EUCOMM)Wtsi | heterozygote | Early adult | 6.26x10-5 |
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External links
No external links available for Tial1.
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Tial1tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
Tial1tm1b(EUCOMM)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |