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Gene: Uqcrc1 MGI:107876

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Gene Summary

Name:
ubiquinol-cytochrome c reductase core protein 1
Synonyms:
1110032G10Rik

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IMPC Data Collections

IMPC Phenotype Summary

Significant
Not Significant
Not tested

View all our phenotype data below

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

Phenotype System Allele Zyg Sex Life Stage P Value
embryonic lethality prior to tooth bud stage Uqcrc1em1(IMPC)Bay HOM   E12.5 0.00
preweaning lethality, complete penetrance Uqcrc1em1(IMPC)Bay HOM   Early adult 0.00
decreased exploration in new environment Uqcrc1em1(IMPC)Bay HET Early adult 7.84×10-05

Download data as:  TSV  XLS

Select physiological systems to view:
Viewing: all phenotypes
Select physiological systems to view:
Viewing: all phenotypes

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Phenotype associated images not available

Human diseases caused by Uqcrc1 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

The table below shows human diseases associated to Uqcrc1 by orthology or direct annotation.

Disease Similarity of
phenotypes		 Matching phenotypes Source
Parkinsonism With Polyneuropathy
Depression OMIM:619279

The table below shows human diseases predicted to be associated to Uqcrc1 by phenotypic similarity.

Disease Similarity of
phenotypes		 Matching phenotypes Source
Monoamine Oxidase A Deficiency
Cognitive impairment ORPHA:3057
Parkinsonism With Polyneuropathy
Depression OMIM:619279

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Uqcrc1

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Uqcrc1.

No publications found that use IMPC mice or data for Uqcrc1.

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All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

MGI Allele Allele Type Produced
Uqcrc1tm82015(L1L2_Bact_P) KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors
Uqcrc1em1(IMPC)Bay Exon Deletion Mice

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