Ndufv1 | NADH:ubiquinone oxidoreductase core subunit V1
Physiological systems
18 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Hematopoietic system Behavior/neurological Mortality/aging
15 No significant impact
6 Not tested
Data collections
Gene metrics:6Significant phenotypes
2Associated diseases
Expression examined in:48Adult tissues
25Embryo tissues
decreased hematocrit | 1 supporting dataset | Ndufv1tm1.1(KOMP)Vlcg | heterozygote | Early adult | 1.04x10-6 | ||
decreased erythrocyte cell number | 1 supporting dataset | Ndufv1tm1.1(KOMP)Vlcg | heterozygote | Early adult | 4.59x10-8 | ||
hyperactivity | 1 supporting dataset | Ndufv1tm1.1(KOMP)Vlcg | heterozygote | Early adult | 8.12x10-5 | ||
preweaning lethality, complete penetrance | 1 supporting dataset | Ndufv1tm1.1(KOMP)Vlcg | homozygote | Early adult | N/A * | ||
embryonic lethality prior to organogenesis | 1 supporting dataset | Ndufv1tm1.1(KOMP)Vlcg | homozygote | E9.5 | N/A * | ||
decreased hemoglobin content | 1 supporting dataset | Ndufv1tm1.1(KOMP)Vlcg | heterozygote | Early adult | 1.81x10-7 |
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External links
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Ndufv1tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | es cell mouse |
Ndufv1tm1.1(KOMP)Vlcg | Reporter-tagged deletion allele (post Cre, with no selection cassette) | | mouse |
Ndufv1tm85611(L1L2_Pgk_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |