Tubb4a | tubulin, beta 4A class IVA
Physiological systems
18 / 24 physiological systems tested
1 Significantly impacted by the knock-out
Homeostasis/metabolism
17 No significant impact
6 Not tested
Data collections
Gene metrics:1Significant phenotypes
4Associated diseases
Expression examined in:48Adult tissues
50Embryo tissues
decreased fasting circulating glucose level | 1 supporting dataset | Tubb4atm1.1(KOMP)Wtsi | homozygote | Early adult | 3.2x10-7 |
| | | | | | | | | |
adrenal gland | heterozygote | n/a | 0% (0/2) | 0.7% (4/570) |
aorta | heterozygote | n/a | 0% (0/2) | 0.19% (1/533) |
brain | heterozygote | Section images | 100% (2/2) | 0.86% (5/579) |
brainstem | heterozygote | Section images | 100% (2/2) | 0.41% (2/490) |
brown adipose tissue | heterozygote | n/a | 0% (0/2) | 0% (0/588) |
cartilage tissue | heterozygote | n/a | 0% (0/2) | 0.22% (1/454) |
cerebellum | heterozygote | Section images | 100% (2/2) | 0.56% (3/532) |
cerebral cortex | heterozygote | Section images | 100% (2/2) | 0.41% (2/491) |
epididymis | heterozygote | n/a | 0% (0/1) | 87.5% (21/24) |
esophagus | heterozygote | n/a | 0% (0/2) | 1.67% (7/419) |
External links
No external links available for Tubb4a.
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Tubb4atm1(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | targeting vector ES Cell mouse |
Tubb4atm1.1(KOMP)Wtsi | Reporter-tagged deletion allele (post Cre, with no selection cassette) | | mouse |
Tubb4atm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
Tubb4atm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |
Tubb4atm2a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
Tubb4atm2e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |