Gene: Ctsk

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Name
cathepsin K
MGI ID
MGI:107823
Synonyms
Cat K catK
Viability
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
increased circulating alkaline phosphatase level Ctsktm1b(EUCOMM)Hmgu HOM Early adult 2.77×10-05
decreased prepulse inhibition Ctsktm1b(EUCOMM)Hmgu HOM Early adult 1.45×10-17
increased grip strength Ctsktm1b(EUCOMM)Hmgu HOM Early adult 9.40×10-06
abnormal uterus morphology Ctsktm1b(EUCOMM)Hmgu HOM Early adult 0.00
short tibia Ctsktm1b(EUCOMM)Hmgu HOM Early adult 4.87×10-08
increased bone mineral density Ctsktm1b(EUCOMM)Hmgu HOM Early adult 3.54×10-09
increased bone mineral content Ctsktm1b(EUCOMM)Hmgu HOM   Early adult 6.98×10-05

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Viewing: all phenotypes

 Expression

Expression data not available

 Associated Images

Gross Pathology and Tissue Collection
9 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images
X-ray: XRay Images Skull Lateral Orientation
10 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
Histopathology
10 Images
X-ray: XRay Images Whole Body Dorso Ventral
10 Images
Immunophenotyping: Panel A FCS file(s)
3 Images
Eye Morphology: Images Ophthalmoscopy
4 Images
Immunophenotyping: Panel B FCS file(s)
3 Images

 Disease Models

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 Histopathology

Phenotype Allele Zygosity Sex Life Stage
Testes - process of degenerative change Ctsktm1b(EUCOMM)Hmgu HOM Early adult
Tibia - developmental and structural abnormality Ctsktm1b(EUCOMM)Hmgu HOM Early adult
Femur - developmental and structural abnormality Ctsktm1b(EUCOMM)Hmgu HOM Early adult
Epididymis - hypoplasia Ctsktm1b(EUCOMM)Hmgu HOM Early adult

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MGI Allele Allele Type Produced
Ctsktm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Ctsktm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells
Ctsktm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice, Tissue

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