Dctn1 - dynactin 1 | International Mouse Phenotyping Consortium

Genes Phenotypes

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Gene: Dctn1

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Name

dynactin 1

MGI ID

MGI:107745

Synonyms

p150 Glued p150

Viability

Homozygous - Lethal

Embryo viewer

N/A

Other links

MGI Ensembl

Significant phenotypes (4) Measurements chart (280) All data table (331)

Expression & images (0) Disease models (0) Order (1)

Significant

Not Significant

Not tested

View body weight measurements

Phenotype	System	Allele	Zyg	Sex	Life Stage	P Value
preweaning lethality, complete penetrance		Dctn1^{tm1a(EUCOMM)Wtsi}	HOM		Early adult	0.00
increased circulating creatinine level		Dctn1^{tm1a(EUCOMM)Wtsi}	HET		Early adult	6.95×10^-07
decreased caudal vertebrae number		Dctn1^{tm1a(EUCOMM)Wtsi}	HET		Early adult	0.00
decreased effector memory CD4-positive, alpha-beta T cell number		Dctn1^{tm1a(EUCOMM)Wtsi}	HET		Early adult	3.41×10^-05

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Viewing: all phenotypes

Select physiological systems to view:

Viewing: all phenotypes

Expression

Expression data not available

Associated Images

X-ray: XRay Images Whole Body Dorso Ventral
42 Images

X-ray: XRay Images Whole Body Lateral Orientation
28 Images

X-ray: XRay Images Forepaw
13 Images

X-ray: XRay Images Skull Lateral Orientation
13 Images

X-ray: XRay Images Skull Dorso Ventral Orientation
15 Images

Legacy Phenotype Associated Images

Dctn1^{tm1a(EUCOMM)Wtsi}
WT, Female, WTSI

Dctn1^{tm1a(EUCOMM)Wtsi}
WT, Female, WTSI

Dctn1^{tm1a(EUCOMM)Wtsi}
WT, Female, WTSI

Dctn1^{tm1a(EUCOMM)Wtsi}
WT, Female, WTSI

Dctn1^{tm1a(EUCOMM)Wtsi}
HET, Female, WTSI

View all 165 images

Dctn1^{tm1a(EUCOMM)Wtsi}
right eye, WT, Female, WTSI

Dctn1^{tm1a(EUCOMM)Wtsi}
left eye, WT, Female, WTSI

Dctn1^{tm1a(EUCOMM)Wtsi}
right eye, WT, Female, WTSI

Dctn1^{tm1a(EUCOMM)Wtsi}
right eye, WT, Female, WTSI

Dctn1^{tm1a(EUCOMM)Wtsi}
left eye, WT, Female, WTSI

View all 9 images

Disease Models

By Annotation and Orthology (0)
By phenotypic Similarity (0)

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MGI Allele	Allele Type	Produced
Dctn1^{tm1a(EUCOMM)Wtsi}	KO first allele (reporter-tagged insertion with conditional potential)	Mice, Targeting vectors, ES Cells

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