Not currently registered for phenotyping at IMPC
Phenotyping is currently not planned for a knockout strain of this gene.
Gene Summary
IMPC Data Collections
- No Body Weight Data
- No Embryo Imaging Data
- No Viability Data
Phenotyping is currently not planned for a knockout strain of this gene.
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
The table below shows human diseases associated to Igtp by orthology or direct annotation.
Disease | Similarity of phenotypes |
Matching phenotypes | Source |
---|---|---|---|
Inflammatory Bowel Disease (Crohn Disease) 19 | OMIM:612278 |
The table below shows human diseases predicted to be associated to Igtp by phenotypic similarity.
Disease | Similarity of phenotypes |
Matching phenotypes | Source |
---|---|---|---|
Immunodeficiency 35 | Recurrent respiratory infections, Recurrent viral infections, Recurrent mycobacterial infections,... | OMIM:611521 | |
Immune Deficiency, Familial Variable | Decreased circulating IgG level, Recurrent infections, Decreased circulating IgA level | OMIM:146830 | |
Inflammatory Bowel Disease (Crohn Disease) 19 | OMIM:612278 |
The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Igtp.
There are 1 publication which use IMPC produced mice or data.
Title | Journal | IMPC Allele | PubMed ID |
---|---|---|---|
A conditional knockout resource for the genome-wide study of mouse gene function. | Nature (June 2011) | Igtptm1a(KOMP)Wtsi | PMC3572410 |
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
MGI Allele | Allele Type | Produced |
---|---|---|
Igtptm1e(KOMP)Wtsi | Targeted, non-conditional allele | ES Cells |
Igtptm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | Targeting vectors, ES Cells |
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