Genes Phenotypes

Gene: Myo10

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Name
myosin X
MGI ID
MGI:107716
Synonyms
myosin-X D15Ertd600e
Viability
Homozygous - Viable
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (20) Measurements chart (327) All data table (937)
Expression & images (0) Disease models (0) Order (3)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal retina morphology Myo10tm2(KOMP)Wtsi HOM Early adult 4.58×10-05
abnormal digit morphology Myo10tm2(KOMP)Wtsi HOM Early adult 8.02×10-28
abnormal lens morphology Myo10tm2(KOMP)Wtsi HOM Early adult 1.19×10-07
abnormal response to new environment Myo10tm2(KOMP)Wtsi HOM Early adult 5.31×10-05
fused cornea and lens Myo10tm2(KOMP)Wtsi HOM Early adult 3.06×10-15
abnormal circulating iron level Myo10tm2(KOMP)Wtsi HOM Early adult 5.35×10-06
impaired pupillary reflex Myo10tm2(KOMP)Wtsi HOM Early adult 6.91×10-06
abnormal iris morphology Myo10tm2(KOMP)Wtsi HOM Early adult 5.18×10-06
abnormal tail morphology Myo10tm2(KOMP)Wtsi HOM Early adult 5.79×10-05
corneal opacity Myo10tm2(KOMP)Wtsi HOM Early adult 1.25×10-13
abnormal cornea morphology Myo10tm2(KOMP)Wtsi HOM Early adult 3.62×10-11
abnormal hematocrit Myo10tm2(KOMP)Wtsi HOM Early adult 1.87×10-05
abnormal coat/hair pigmentation Myo10tm2(KOMP)Wtsi HOM Early adult 1.94×10-22
decreased circulating iron level Myo10tm2(KOMP)Wtsi HOM Early adult 4.24×10-05
fused phalanges Myo10tm2(KOMP)Wtsi HOM Early adult 8.02×10-28
abnormal circulating alkaline phosphatase level Myo10tm2(KOMP)Wtsi HOM Early adult 1.65×10-06
abnormal circulating creatinine level Myo10tm2(KOMP)Wtsi HOM Early adult 0.00
cataract Myo10tm2(KOMP)Wtsi HOM Early adult 1.19×10-07
persistence of hyaloid vascular system Myo10tm2(KOMP)Wtsi HOM Early adult 7.76×10-28
abnormal erythrocyte cell number Myo10tm2(KOMP)Wtsi HOM Early adult 1.74×10-05

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 Expression

Expression data not available

 Associated Images

Ear epidermis immunophenotyping
12 Images
DSS Histology
12 Images
Anti-nuclear antibody assay
6 Images
Eye Morphology: Images Ophthalmoscopy
14 Images
Eye Morphology: Images Slit Lamp
14 Images
Legacy Phenotype Associated Images
Myo10tm2(KOMP)Wtsi
WT, Male, WTSI
Myo10tm2(KOMP)Wtsi
WT, Male, WTSI
Myo10tm2(KOMP)Wtsi
WT, Male, WTSI
Myo10tm2(KOMP)Wtsi
WT, Male, WTSI
Myo10tm2(KOMP)Wtsi
HOM, Male, WTSI

View all 83 images

Myo10tm2(KOMP)Wtsi
abnormal coat/hair pigmentation, abnormal dorsoventral coat patterning, HOM, Male, WTSI
Myo10tm2(KOMP)Wtsi
interdigital webbing, HOM, Male, WTSI
Myo10tm2(KOMP)Wtsi
interdigital webbing, HOM, Female, WTSI
Myo10tm2(KOMP)Wtsi
abnormal ventral coat pigmentation, abnormal dorsoventral coat patterning, HOM, Female, WTSI
Myo10tm2(KOMP)Wtsi
interdigital webbing, HOM, Female, WTSI

View all 40 images

Myo10tm2(KOMP)Wtsi
mydriasis, abnormal pupil morphology, HOM, Female, WTSI
Myo10tm2(KOMP)Wtsi
Fused cornea and lens, HOM, Female, WTSI
Myo10tm2(KOMP)Wtsi
persistence of hyaloid vascular system, HOM, Male, WTSI
Myo10tm2(KOMP)Wtsi
persistence of hyaloid vascular system, HOM, Female, WTSI
Myo10tm2(KOMP)Wtsi
corneal vascularization, HOM, Male, WTSI

View all 28 images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Myo10tm2(KOMP)Wtsi Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells
Myo10tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Myo10tm242153(L1L2_Bact_P) Targeting vectors