Genes Phenotypes

Gene: Myo10

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Name
myosin X
MGI ID
MGI:107716
Synonyms
D15Ertd600e myosin-X
Viability
Homozygous - Viable
View
N/A
Other links
MGI   Ensembl  
Significant phenotypes (17) Measurements chart (411) All data table (545)
Expression & images (0) Disease models (0) Order (3)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal retina morphology Myo10tm2(KOMP)Wtsi HOM postnatal 5.13×10-05
abnormal digit morphology Myo10tm2(KOMP)Wtsi HOM postnatal 4.50×10-20
abnormal lens morphology Myo10tm2(KOMP)Wtsi HOM postnatal 9.89×10-08
abnormal response to new environment Myo10tm2(KOMP)Wtsi HOM postnatal 8.15×10-05
fused cornea and lens Myo10tm2(KOMP)Wtsi HOM postnatal 3.12×10-14
decreased caudal vertebrae number Myo10tm2(KOMP)Wtsi HOM postnatal 3.04×10-05
fused phalanges Myo10tm2(KOMP)Wtsi HOM postnatal 4.50×10-20
abnormal cornea morphology Myo10tm2(KOMP)Wtsi HOM postnatal 3.96×10-11
decreased circulating creatinine level Myo10tm2(KOMP)Wtsi HOM postnatal 2.00×10-07
persistence of hyaloid vascular system Myo10tm2(KOMP)Wtsi HOM postnatal 3.92×10-15
decreased circulating iron level Myo10tm2(KOMP)Wtsi HOM postnatal 8.47×10-05
cataract Myo10tm2(KOMP)Wtsi HOM postnatal 9.89×10-08
abnormal iris morphology Myo10tm2(KOMP)Wtsi HOM postnatal 5.83×10-06
increased or absent threshold for auditory brainstem response Myo10tm2(KOMP)Wtsi HOM postnatal 0.00
impaired pupillary reflex Myo10tm2(KOMP)Wtsi HOM postnatal 7.85×10-06
corneal opacity Myo10tm2(KOMP)Wtsi HOM postnatal 4.83×10-13
abnormal coat/hair pigmentation Myo10tm2(KOMP)Wtsi HOM postnatal 1.83×10-14

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Viewing: all phenotypes

 Expression

Expression data not available

 Associated Images

X-ray: XRay Images Dorso Ventral
40 Images
X-ray: XRay Images Lateral Orientation
28 Images
Eye Morphology: Images Slit Lamp
14 Images
X-ray: XRay Images Skull Lateral Orientation
14 Images
X-ray: XRay Images Forepaw
14 Images
Eye Morphology: Images Ophthalmoscopy
14 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
12 Images
DSS Histology
12 Images
Anti-nuclear antibody assay
6 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Myo10tm242153(L1L2_Bact_P) Targeting vectors
Myo10tm1a(KOMP)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells
Myo10tm2(KOMP)Wtsi Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells

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