Ifnar1 | interferon (alpha and beta) receptor 1

GeneMGI:107658Synonyms: Ifar, IFN-alpha/betaR, +1 more

Physiological systems

18 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Integument Hematopoietic system Skeleton

13 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:8Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased circulating amylase level1 supporting datasetIfnar1tm2a(EUCOMM)WtsihomozygoteEarly adult4.76x10-10 
increased circulating creatinine level1 supporting datasetIfnar1tm2a(EUCOMM)WtsihomozygoteEarly adult4.32x10-7 
abnormal vibrissa morphology1 supporting datasetIfnar1tm2a(EUCOMM)WtsihomozygoteEarly adult6.98x10-5 
increased bone mineral content1 supporting datasetIfnar1tm2a(EUCOMM)WtsihomozygoteEarly adult6.71x10-5 
improved glucose tolerance1 supporting datasetIfnar1tm2a(EUCOMM)WtsihomozygoteEarly adult1.16x10-6 
decreased KLRG1-positive NK cell number1 supporting datasetIfnar1tm2a(EUCOMM)WtsihomozygoteEarly adultN/A * 
decreased monocyte cell number1 supporting datasetIfnar1tm2a(EUCOMM)WtsihomozygoteEarly adultN/A * 
decreased circulating fructosamine level1 supporting datasetIfnar1tm2a(EUCOMM)WtsihomozygoteEarly adult8.09x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ifnar1tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Ifnar1tm2a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse

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