The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.
An assay measuring the expression of lacZ shows the tissue where the gene is expressed.
|Adrenal gland||N/A||heterozygote||0.0% (0 of 1)|
|Aorta||N/A||heterozygote||0.0% (0 of 1)|
|Blood vessel||N/A||heterozygote||0.0% (0 of 1)|
|Bone||N/A||heterozygote||0.0% (0 of 1)|
|Brain||N/A||heterozygote||0.0% (0 of 1)|
|Brainstem||N/A||heterozygote||0.0% (0 of 1)|
|Brown adipose tissue||N/A||heterozygote||0.0% (0 of 1)|
|Cartilage tissue||N/A||heterozygote||0.0% (0 of 1)|
|Cerebellum||N/A||heterozygote||0.0% (0 of 1)|
|Cerebral cortex||N/A||heterozygote||0.0% (0 of 1)|
|Eye||N/A||heterozygote||0.0% (0 of 1)|
|Gall bladder||N/A||heterozygote||0.0% (0 of 1)|
|Heart||N/A||heterozygote||0.0% (0 of 1)|
|Hippocampus||N/A||heterozygote||0.0% (0 of 1)|
|Hypothalamus||N/A||heterozygote||0.0% (0 of 1)|
|Kidney||N/A||heterozygote||100% (1 of 1)|
|Large intestine||N/A||heterozygote||0.0% (0 of 1)|
|Liver||N/A||heterozygote||0.0% (0 of 1)|
|Lower urinary tract||N/A||heterozygote||0.0% (0 of 1)|
|Lung||N/A||heterozygote||0.0% (0 of 1)|
|Lymph node||N/A||heterozygote||0.0% (0 of 1)|
|Mammary gland||N/A||heterozygote||0.0% (0 of 1)|
|Esophagus||N/A||heterozygote||0.0% (0 of 1)|
|Olfactory lobe||N/A||heterozygote||0.0% (0 of 1)|
|Ovary||N/A||heterozygote||0.0% (0 of 1)|
|Oviduct||N/A||heterozygote||0.0% (0 of 1)|
|Pancreas||N/A||heterozygote||0.0% (0 of 1)|
|Parathyroid gland||N/A||heterozygote||0.0% (0 of 1)|
|Peripheral nervous system||N/A||heterozygote||0.0% (0 of 1)|
|Peyer's patch||N/A||heterozygote||0.0% (0 of 1)|
|Pituitary gland||N/A||heterozygote||0.0% (0 of 1)|
|Prostate gland||N/A||heterozygote||Not available|
|Skeletal muscle tissue||N/A||heterozygote||0.0% (0 of 1)|
|Skin||N/A||heterozygote||0.0% (0 of 1)|
|Small intestine||N/A||heterozygote||0.0% (0 of 1)|
|Spinal cord||N/A||heterozygote||0.0% (0 of 1)|
|Spleen||N/A||heterozygote||0.0% (0 of 1)|
|Stomach||N/A||heterozygote||0.0% (0 of 1)|
|Striatum||N/A||heterozygote||0.0% (0 of 1)|
|Thymus||N/A||heterozygote||0.0% (0 of 1)|
|Thyroid gland||N/A||heterozygote||0.0% (0 of 1)|
|Trachea||N/A||heterozygote||0.0% (0 of 1)|
|Uterus||N/A||heterozygote||0.0% (0 of 1)|
|White adipose tissue||N/A||heterozygote||0.0% (0 of 1)|
Background staining occurs in wild type mice and embryos at an incidental rate.
|Anatomy||Background staining in controls (WT)|
|brown adipose tissue||0.0%|
|lower urinary tract||0.0%|
|peripheral nervous system||0.0%|
|skeletal muscle tissue|
|white adipose tissue||0.0%|
Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.
Legacy Phenotype Associated Images
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Npat.
There are 6 publications which use IMPC produced mice or data.
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
|MGI Allele||Allele Type||Produced|
|Npattm1(KOMP)Vlcg||Reporter-tagged deletion allele (with selection cassette)||ES Cells|
|Npattm1a(EUCOMM)Wtsi||KO first allele (reporter-tagged insertion with conditional potential)||Mice, Targeting vectors, ES Cells|
|Npattm1e(EUCOMM)Wtsi||Targeted, non-conditional allele||ES Cells|
|Npattm1b(EUCOMM)Wtsi||Reporter-tagged deletion allele (with selection cassette)||Mice|