The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.
|Phenotype||System||Allele||Zyg||Sex||Life Stage||P Value|
|preweaning lethality, complete penetrance||Hmgcs1em1(IMPC)J||HOM||Early adult||0.00|
|abnormal auditory brainstem response||Hmgcs1em1(IMPC)J||HET||Early adult||7.94×10-11|
|increased circulating alanine transaminase level||Hmgcs1em1(IMPC)J||HET||Early adult||8.17×10-07|