Gene: Sipa1

Name
signal-induced proliferation associated gene 1
MGI ID
MGI:107576
Synonyms
SPA-1
View
N/A
Other links
View data by physiological system
Significant
Not Significant
Not tested

Filtered by: all phenotypes

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Allele Center Procedure / Parameter Zygosity Mutants Statistical
Method
P Value Status
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Tail - thickness HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Forelimb digit - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Clinical Chemistry / Alanine aminotransferase HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.404 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Coat - hair distribution - back HOM 8f:8m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Eye Morphology / Bulging eye HOM 8f:8m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Forelimb nail - shape HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Skin texture - whole body HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Trunk curl HOM 8f:8m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Clinical Chemistry / Creatinine HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.275 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Eye Morphology / Iris/Pupil HOM 8f:8m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Hematology / Mean cell hemoglobin concentration HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.930 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell X-ray / Radius HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell X-ray / Fibula HOM 5f:5m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Hematology / Mean platelet volume HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.506 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Hematology / Eosinophil differential count HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.813 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Open Field / Percentage center time HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.927 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Auditory Brain Stem Response / 6kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell X-ray / Shape of vertebrae HOM 5f:5m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell X-ray / Brachydactyly HOM 5f:5m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Vibrissae - presence HOM 8f:8m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Thyroid HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Thyroid HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Thyroid HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Thyroid HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Lower teeth appearance HOM 8f:8m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell X-ray / Scapulae HOM 5f:5m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Eye Morphology / Lens Opacity HOM 8f:8m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Skin texture - back paws HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Forelimbs - shape HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Open Field / Periphery distance travelled HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.851 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Eye Morphology / Retina (combined) HOM 8f:8m Not processed Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell X-ray / Zygomatic bone HOM 5f:5m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Spleen HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Spleen HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Spleen HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Spleen HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Clinical Chemistry / Calcium HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.512 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell X-ray / Shape of ribs HOM 5f:5m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Epididymis HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Epididymis HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Epididymis HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Epididymis HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Contact righting HOM 8f:8m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Hematology / Hematocrit HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.546 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Hindlimb nail - number HOM 8f:8m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Skin color - ear HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Esophagus HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Esophagus HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Esophagus HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Esophagus HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Grip Strength / Forelimb and hindlimb grip strength normalised against body weight HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.232 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - head HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Intraperitoneal glucose tolerance test (IPGTT) / Area under glucose response curve HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.769 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Clinical Chemistry / Creatine kinase HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.894 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Coat - color - abdomen HOM 8f:8m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Eye Morphology / Pupil Dilation HOM 8f:8m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI3 HOM 8f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.00859 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Clinical Chemistry / Potassium HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.107 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Body Composition (DEXA lean/fat) / Fat mass HOM 3f:8m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_DXA_002_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Auditory Brain Stem Response / 30kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Clinical Chemistry / Phosphorus HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.960 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Hindpaw - shape HOM 8f:8m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Tremor HOM 8f:8m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Viability Primary Screen / Outcome HOM 46f:46m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Genitalia - morphology HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Hematology / Large Unstained Cell (LUC) count HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0784 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Lymph node HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Lymph node HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Lymph node HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Lymph node HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Brain HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Brain HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Brain HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Brain HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Hematology / Lymphocyte cell count HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.197 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Head morphology HOM 8f:8m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Indirect Calorimetry / Respiratory Exchange Ratio HOM 0f:8m Not processed 1.00 FAILED - testDataset returned an error, check log file
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Upper teeth appearance HOM 8f:8m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Open Field / Center distance travelled HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.794 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Auditory Brain Stem Response / 18kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Eye Morphology / Corneal vascularization HOM 8f:8m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Eye Morphology / Retinal Blood Vessels Pattern HOM 8f:8m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Clinical Chemistry / Triglycerides HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0544 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell X-ray / Clavicle HOM 5f:5m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Hematology / Platelet count HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.00706 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Activity (body position) HOM 8f:8m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Liver HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Liver HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Liver HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Liver HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Hindlimb digit - size HOM 8f:8m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell X-ray / Digit integrity HOM 5f:5m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Thymus HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Thymus HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Thymus HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Thymus HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Skin texture - snout HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Clinical Chemistry / Total protein HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0216 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Eye Morphology / Pupil Position HOM 8f:8m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Body Composition (DEXA lean/fat) / Fat/Body weight HOM 3f:8m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_DXA_009_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Hindlimbs - position HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Open Field / Latency to center entry HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.366 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Eye Morphology / Eyelid closure HOM 8f:8m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Forelimbs - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell X-ray / Fusion of vertebrae HOM 5f:5m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Mammary gland HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Mammary gland HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Mammary gland HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Mammary gland HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Tail - morphology HOM 8f:8m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell X-ray / Tibia HOM 5f:5m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Coat - color pattern - abdomen HOM 8f:8m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Clinical Chemistry / Aspartate aminotransferase HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.953 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Hindlimb nail - length HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Hematology / Eosinophil cell count HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.441 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Vocalization HOM 8f:8m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Grip Strength / Forelimb and hindlimb grip strength measurement mean HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.265 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Hematology / Hemoglobin HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.216 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Open Field / Whole arena resting time HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.970 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell X-ray / Syndactylism HOM 5f:5m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Teeth presence HOM 8f:8m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Eye Morphology / Lens HOM 8f:8m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Grip Strength / Forelimb grip strength normalised against body weight HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.853 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Head size HOM 8f:8m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Coat - color pattern - back HOM 8f:8m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Eye Morphology / Optic Disc HOM 8f:8m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Open Field / Center average speed HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.704 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Eye Morphology / Narrow eye opening HOM 8f:8m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Clinical Chemistry / Sodium HOM 8f:8m Not processed 1.00 FAILED - Insufficient variability in dependent variable 'IMPC_CBC_001_001' for MM/TF framework. Fisher Exact Test can be better way to do the analysis.
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Organ Weight / Heart weight HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.701 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Forepaw - shape HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Body Composition (DEXA lean/fat) / Bone Mineral Content (excluding skull) HOM 3f:8m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_DXA_005_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Hematology / Neutrophil differential count HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.158 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Prostate HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Prostate HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Prostate HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Prostate HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Skin color - snout HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Skin HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Skin HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Skin HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Skin HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - back HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Lung HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Lung HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Lung HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Lung HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Clinical Chemistry / HDL-cholesterol HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0224 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Eye Morphology / Persistence of hyaloid vascular system HOM 8f:8m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI2 HOM 8f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.195 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Acoustic Startle and Pre-pulse Inhibition (PPI) / Response amplitude - S HOM 8f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.701 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Eye Morphology / Pupil Shape HOM 8f:8m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Open Field / Periphery average speed HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.970 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Fertility of Homozygous Knock-out Mice / Gross Findings Male HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Eye Morphology / Eye HOM 8f:8m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell X-ray / Processes on vertebrae HOM 5f:5m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell X-ray / Maxilla/Pre-maxilla HOM 5f:5m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Hematology / Lymphocyte differential count HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.132 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Pancreas HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Pancreas HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Pancreas HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Pancreas HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Mouth morphology HOM 8f:8m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Hematology / Monocyte differential count HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.659 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Head bobbing HOM 8f:8m Fisher Exact Test framework 0.000322 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Spinal cord HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Spinal cord HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Spinal cord HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Spinal cord HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Body Composition (DEXA lean/fat) / Lean/Body weight HOM 3f:8m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_DXA_008_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell X-ray / Number of ribs right HOM 5f:1m 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Skin texture - ear HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Open Field / Distance travelled - total HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.934 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Snout size HOM 8f:8m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Clinical Chemistry / Alpha-amylase HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.000196 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Auditory Brain Stem Response / Click-evoked ABR threshold HOM 2f:2m 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Eye Morphology / Synechia HOM 8f:8m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Clinical Chemistry / Iron HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.354 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Auditory Brain Stem Response / 24kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Clinical Chemistry / Total cholesterol HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.119 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Genitalia - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Open Field / Periphery permanence time HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.896 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Clinical Chemistry / Albumin HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.108 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Forelimb nail - length HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Intraperitoneal glucose tolerance test (IPGTT) / Initial response to glucose challenge HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.463 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Aggression HOM 8f:8m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Open Field / Number of center entries HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.919 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell X-ray / Pelvis HOM 5f:5m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Adrenal gland HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Adrenal gland HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Adrenal gland HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Adrenal gland HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Grip Strength / Forelimb grip strength measurement mean HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.989 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Hindlimbs - shape HOM 8f:8m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Startle response HOM 8f:8m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Urinary bladder HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Urinary bladder HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Urinary bladder HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Urinary bladder HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Eye Morphology / Eyelid morphology HOM 8f:8m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell X-ray / Shape of spine HOM 5f:5m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Forelimb digit - shape HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Gall bladder HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Gall bladder HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Gall bladder HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Gall bladder HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Hematology / Mean cell volume HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0147 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Coat - color - back HOM 8f:8m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell X-ray / Femur HOM 5f:5m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Eye Morphology / Cornea HOM 8f:8m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Open Field / Center permanence time HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.927 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Auditory Brain Stem Response / 12kHz-evoked ABR Threshold HOM 2f:2m 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Hindpaw - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Hematology / Basophil cell count HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.328 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Body Composition (DEXA lean/fat) / Bone Mineral Density (excluding skull) HOM 3f:8m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_DXA_004_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Upper lip morphology HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Locomotor activity HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0179 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Hematology / Red blood cell count HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.905 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Skeletal muscle HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Skeletal muscle HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Skeletal muscle HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Skeletal muscle HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Skin texture - tail HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Vibrissae - appearance HOM 8f:8m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Eye Morphology / Iris Pigmentation HOM 8f:8m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Acoustic Startle and Pre-pulse Inhibition (PPI) / % Pre-pulse inhibition - PPI1 HOM 8f:8m Mixed Model framework, generalized least squares, equation withoutWeight 0.534 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Eye Morphology / Retinal Blood Vessels HOM 8f:8m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell X-ray / Mandibles HOM 5f:5m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Hematology / Neutrophil cell count HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.0289 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Seminal vesicle HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Seminal vesicle HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Seminal vesicle HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Seminal vesicle HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell X-ray / Humerus HOM 5f:5m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Skin color - back paws HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Large intestine HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Large intestine HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Large intestine HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Large intestine HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Limb grasp HOM 8f:8m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Skin color - whole body HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell X-ray / Number of digits HOM 5f:1m 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Coat - hair distribution - abdomen HOM 8f:8m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Clinical Chemistry / Urea (Blood Urea Nitrogen - BUN) HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.222 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Coat - color pattern - head HOM 8f:8m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Open Field / Periphery resting time HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.953 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Genitalia - presence HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Hindlimb nail - shape HOM 8f:8m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell X-ray / Ulna HOM 5f:5m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Coat - hair distribution - head HOM 8f:8m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Uterus HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Uterus HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Uterus HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Uterus HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Organ Weight / Spleen weight HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.168 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Clinical Chemistry / Fructosamine HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.136 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Clinical Chemistry / Alkaline phosphatase HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0837 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Hindlimb digit - number HOM 8f:8m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Stomach HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Stomach HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Stomach HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Stomach HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Tail - length HOM 8f:8m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Eye Morphology / Eye Hemorrhage or Blood Presence HOM 8f:8m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Hematology / Monocyte cell count HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.430 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Unexpected behaviors HOM 8f:8m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell X-ray / Teeth HOM 5f:5m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell X-ray / Number of ribs left HOM 5f:1m 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Hindlimbs - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Skin texture - front paws HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Body Composition (DEXA lean/fat) / Bone Area HOM 3f:8m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_DXA_010_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Eye Morphology / Fusion between cornea and lens HOM 8f:8m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Coat - color - head HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Hematology / Mean corpuscular hemoglobin HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.319 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Hindlimb digit - shape HOM 8f:8m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Hematology / Large Unstained Cell (LUC) differential count HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.226 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Intraperitoneal glucose tolerance test (IPGTT) / Fasted blood glucose concentration HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.311 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Forepaw - size HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Heart HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Heart HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Heart HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Heart HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Clinical Chemistry / Total bilirubin HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0820 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Forelimbs - position HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell X-ray / Fusion of ribs HOM 5f:5m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Body Composition (DEXA lean/fat) / BMC/Body weight HOM 3f:8m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_DXA_007_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Lower lip morphology HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Trachea HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Trachea HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Trachea HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Trachea HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Hematology / Basophil differential count HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.402 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Skin color - front paws HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Testes HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Testes HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Testes HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Testes HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Coat - hair texture / appearance - abdomen HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Open Field / Center resting time HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.891 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Clinical Chemistry / Glucose HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.0999 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Eye Morphology / Retinal Blood Vessels Structure HOM 8f:8m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Fertility of Homozygous Knock-out Mice / Gross Findings Female HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell X-ray / Joints HOM 5f:5m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell X-ray / Skull shape HOM 5f:5m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Forelimb nail - number HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Gait HOM 8f:8m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Kidney HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Kidney HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Kidney HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Kidney HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Hematology / Red blood cell distribution width HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withWeight 0.149 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Ears HOM 8f:8m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Small intestine HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Small intestine HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Small intestine HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Small intestine HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Forelimb digit - number HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Tail - presence HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Clinical Chemistry / Chloride HOM 8f:8m Not processed 1.00 FAILED - Insufficient variability in dependent variable 'IMPC_CBC_003_001' for MM/TF framework. Fisher Exact Test can be better way to do the analysis.
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Body Composition (DEXA lean/fat) / Lean mass HOM 3f:8m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_DXA_003_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell X-ray / Tibia length HOM 4f:1m Not processed 1.00 FAILED - Not enough data points in dependent variable 'IMPC_XRY_033_001' for genotype/sex combinations to allow the application of MM/TF framework. Threshold used: 4.
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Eye Morphology / Pupil Light Response HOM 8f:8m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Open Field / Whole arena average speed HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.929 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Eye Morphology / Corneal opacity HOM 8f:8m Fisher Exact Test framework 1.00 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Ovary HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Ovary HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Ovary HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Ovary HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Eye with optic nerve HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Eye with optic nerve HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Eye with optic nerve HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Gross Pathology and Tissue Collection / Eye with optic nerve HOM f:m Supplied as data Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Hematology / White blood cell count HOM 8f:8m Mixed Model framework, linear mixed-effects model, equation withoutWeight 0.108 Success
Sipa1tm1b(EUCOMM)Hmgu MRC Harwell Combined SHIRPA and Dysmorphology / Skin color - tail HOM 8f:8m Fisher Exact Test framework 1.00 Not tested (No variation) - OK

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No N/A
Bone 2 No N/A
Brain 2 No N/A
Brainstem 2 No N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No N/A
Cerebral cortex 2 No N/A
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No N/A
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Kidney 2 No  (18/584)  (2/2)  Wholemount images
Large intestine 2 No  (10/584) N/A
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No N/A
Lymph node 2 No  (2/2)  Wholemount images
Mammary gland 2 No N/A
Olfactory lobe 2 No N/A
Oral epithelium 2 No N/A
Ovary 2 No  (1/584) N/A
Oviduct 2 No  (1/2)  Wholemount images
Pancreas 2 No  (5/584) N/A
Parathyroid gland 2 No N/A
Peripheral nervous system 2 No  (2/2)  Wholemount images
Peyer's patch 2 No  (2/2)  Wholemount images
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No N/A
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584)  (2/2)  Wholemount images
Striatum 2 No N/A
Testis 2 No  (2/584)  (1/2)  Wholemount images
Thymus 2 No N/A
Thyroid gland 2 No  (15/584) N/A
Trachea 2 No N/A
Uterus 2 No  (1/2)  Wholemount images
Vascular system 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/485)  (4/4) N/A
Ear 2  (1/485) N/A
Embryo 2  (1/485)  (4/4) N/A
Eye 2  (1/485)  (2/4) N/A
Foot 2  (1/485)  (3/4) N/A
Forebrain 2  (1/485)  (4/4) N/A
Forelimb 2  (1/485)  (4/4) N/A
Hand 2  (1/485)  (4/4) N/A
Head 2  (5/485)  (4/4) N/A
Heart 2  (1/485)  (2/4) N/A
Hindbrain 2  (6/485)  (4/4) N/A
Hindlimb 2  (1/485)  (4/4) N/A
Liver 2  (1/485)  (2/4) N/A
Lung 2  (1/485)  (2/4) N/A
Mandibular process 2  (1/485)  (2/4) N/A
Maxillary process 2  (1/485)  (2/4) N/A
Midbrain 2  (1/485)  (4/4) N/A
Oral cavity 2  (1/485) N/A
Skin 2  (1/485) N/A
Tail 2  (1/485)  (4/4) N/A
Tail somite 2  (1/485) N/A

 Associated Images

Auditory Brain Stem Response: Click-evoked + 6 to 30kHz tone waveforms (pdf format)
4 Images
Embryo LacZ: LacZ images wholemount
8 Images
Adult LacZ: LacZ Images Wholemount
7 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
12 Images
X-ray: XRay Images Dorso Ventral
12 Images
X-ray: XRay Images Lateral Orientation
12 Images

 Disease Models

No associations by disease annotation and gene orthology found.
Please visit the desktop version to see this section

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Sipa1tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Sipa1tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice

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