Genes Phenotypes

Gene: Irgm1

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Name
immunity-related GTPase family M member 1
MGI ID
MGI:107567
Synonyms
Irgm Ifi1 LRG-47 Iigp3
Viability
N/A
Embryo viewer
N/A
Other links
MGI   Ensembl  
Significant phenotypes (33) Measurements chart (208) All data table (226)
Expression & images (0) Disease models (0) Order (2)
Significant
Not Significant
Not tested
View body weight measurements
Phenotype System Allele Zyg Sex Life Stage P Value
decreased B cell number Irgm1em1(IMPC)Wtsi HOM Early adult 0.00
decreased hematocrit Irgm1em1(IMPC)Wtsi HOM Early adult 4.46×10-18
increased CD4-positive, alpha beta T cell number Irgm1em1(IMPC)Wtsi HOM Early adult 1.00×10-06
increased circulating cholesterol level Irgm1em1(IMPC)Wtsi HOM Early adult 9.11×10-05
increased circulating alkaline phosphatase level Irgm1em1(IMPC)Wtsi HOM Early adult 1.54×10-07
decreased NK T cell number Irgm1em1(IMPC)Wtsi HOM Early adult 2.00×10-07
increased red blood cell distribution width Irgm1em1(IMPC)Wtsi HOM Early adult 0.00
increased neutrophil cell number Irgm1em1(IMPC)Wtsi HOM Early adult 2.05×10-05
decreased circulating fructosamine level Irgm1em1(IMPC)Wtsi HOM Early adult 6.79×10-05
thrombocytopenia Irgm1em1(IMPC)Wtsi HOM Early adult 7.82×10-25
decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number Irgm1em1(IMPC)Wtsi HOM Early adult 0.00
decreased T cell number Irgm1em1(IMPC)Wtsi HOM Early adult 2.05×10-05
decreased NK cell number Irgm1em1(IMPC)Wtsi HOM Early adult 0.00
increased monocyte cell number Irgm1em1(IMPC)Wtsi HOM Early adult 0.00
decreased effector memory CD8-positive, alpha-beta T cell number Irgm1em1(IMPC)Wtsi HOM Early adult 4.60×10-06
decreased mature B cell number Irgm1em1(IMPC)Wtsi HOM Early adult 0.00
decreased circulating glucose level Irgm1em1(IMPC)Wtsi HOM Early adult 2.13×10-05
decreased KLRG1-positive NK cell number Irgm1em1(IMPC)Wtsi HOM Early adult 0.00
decreased circulating serum albumin level Irgm1em1(IMPC)Wtsi HOM Early adult 5.14×10-11
abnormal eye morphology Irgm1em1(IMPC)Wtsi HOM Early adult 5.57×10-07
decreased gamma-delta T cell number Irgm1em1(IMPC)Wtsi HOM Early adult 0.00
decreased erythrocyte cell number Irgm1em1(IMPC)Wtsi HOM Early adult 1.37×10-13
decreased alpha-beta T cell number Irgm1em1(IMPC)Wtsi HOM Early adult 2.19×10-05
decreased CD8-positive, alpha-beta T cell number Irgm1em1(IMPC)Wtsi HOM Early adult 0.00
decreased effector memory CD4-positive, alpha-beta T cell number Irgm1em1(IMPC)Wtsi HOM Early adult 0.00
decreased eosinophil cell number Irgm1em1(IMPC)Wtsi HOM Early adult 0.00
increased lean body mass Irgm1em1(IMPC)Wtsi HOM Early adult 2.90×10-05
decreased leukocyte cell number Irgm1em1(IMPC)Wtsi HOM Early adult 3.63×10-05
increased KLRG1-positive NK cell number Irgm1em1(IMPC)Wtsi HOM Early adult 0.00
decreased hemoglobin content Irgm1em1(IMPC)Wtsi HOM Early adult 1.15×10-05
decreased fasting circulating glucose level Irgm1em1(IMPC)Wtsi HOM Early adult 4.03×10-09
decreased circulating triglyceride level Irgm1em1(IMPC)Wtsi HOM Early adult 5.64×10-06
increased circulating LDL cholesterol level Irgm1em1(IMPC)Wtsi HOM Early adult 4.52×10-06

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 Expression

Expression data not available

 Associated Images

DSS Histology
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 Disease Models

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MGI Allele Allele Type Produced
Irgm1em1(IMPC)Wtsi Exdel Mice
Irgm1tm470641(Ifitm2_intron_L1L2_GT1_LF2A_LacZ_BetactP_neo) Targeting vectors

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