Not currently registered for phenotyping at IMPC

Phenotyping is currently not planned for a knockout strain of this gene.

Gene Summary

Name:
GATA binding protein 6
Synonyms:
N/A

IMPC Data Collections

  • No Body Weight Data
  • No Embryo Imaging Data
  • No Viability Data

IMPC Phenotype Summary

Significant
Not Significant
Not tested

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Phenotype associated images not available

Human diseases caused by Gata6 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

The table below shows human diseases associated to Gata6 by orthology or direct annotation.

Disease Similarity of
phenotypes
Matching phenotypes Source
Tetralogy Of Fallot
Intrauterine growth retardation ORPHA:3303
Heart Defects, Congenital, And Other Congenital Anomalies
Intrauterine growth retardation, Patent ductus arteriosus, Umbilical hernia OMIM:600001
Pancreatic Hypoplasia-Diabetes-Congenital Heart Disease Syndrome
Intrauterine growth retardation, Patent ductus arteriosus, Umbilical hernia ORPHA:2255
Partial Atrioventricular Septal Defect
Patent ductus arteriosus ORPHA:1330
Atrioventricular Septal Defect 5
OMIM:614474
Tetralogy Of Fallot
OMIM:187500
Atrial Septal Defect 9
OMIM:614475
Congenital Diaphragmatic Hernia
ORPHA:2140
Conotruncal Heart Malformations
OMIM:217095
Atrial Septal Defect, Ostium Secundum Type
ORPHA:99103

The table below shows human diseases predicted to be associated to Gata6 by phenotypic similarity.

Disease Similarity of
phenotypes
Matching phenotypes Source
Tetralogy Of Fallot
Intrauterine growth retardation ORPHA:3303
Heart Defects, Congenital, And Other Congenital Anomalies
Intrauterine growth retardation, Patent ductus arteriosus, Umbilical hernia OMIM:600001
Pancreatic Hypoplasia-Diabetes-Congenital Heart Disease Syndrome
Intrauterine growth retardation, Patent ductus arteriosus, Umbilical hernia ORPHA:2255
Partial Atrioventricular Septal Defect
Patent ductus arteriosus ORPHA:1330
Atrioventricular Septal Defect 5
OMIM:614474
Tetralogy Of Fallot
OMIM:187500
Atrial Septal Defect 9
OMIM:614475
Congenital Diaphragmatic Hernia
ORPHA:2140
Conotruncal Heart Malformations
OMIM:217095
Atrial Septal Defect, Ostium Secundum Type
ORPHA:99103

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Gata6

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Gata6.

No publications found that use IMPC mice or data for Gata6.

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MGI Allele Allele Type Produced
Gata6tm108362(L1L2_Bact_P) Targeting vectors

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