Gene: Kcnj11

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Name
potassium inwardly rectifying channel, subfamily J, member 11
MGI ID
MGI:107501
Synonyms
Kir6.2
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
impaired glucose tolerance Kcnj11tm1b(EUCOMM)Wtsi HOM Early adult 6.26×10-07
decreased fasting circulating glucose level Kcnj11tm1b(EUCOMM)Wtsi HOM Early adult 9.27×10-07
abnormal ear morphology Kcnj11tm1b(EUCOMM)Wtsi HOM Early adult 5.76×10-05

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Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (3/590) N/A
Aorta 2 No  (1/590)  (2/2)  Wholemount images
Bone 2 No N/A
Brain 2 No  (3/590)  (2/2)  Wholemount images
Brainstem 2 No  (2/590)  (2/2)  Wholemount images
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cerebellum 2 No  (3/590)  (2/2)  Wholemount images
Cerebral cortex 2 No  (2/590)  (2/2)  Wholemount images
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Heart 2 No  (1/590)  (2/2)  Wholemount images
Hippocampus 2 No  (3/590)  (2/2)  Wholemount images
Hypothalamus 2 No  (2/590)  (2/2)  Wholemount images
Kidney 2 No  (20/590) N/A
Large intestine 2 No  (10/590)  (2/2)  Wholemount images
Liver 2 No N/A
Lower urinary tract 2 No  (1/590) N/A
Lung 2 No  (1/590)  (2/2)  Wholemount images
Lymph node 2 No N/A
Mammary gland 2 No N/A
Olfactory lobe 2 No  (2/590)  (2/2)  Wholemount images
Oral epithelium 2 No N/A
Ovary 2 No  (1/590) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/590)  (2/2)  Wholemount images
Parathyroid gland 2 No  (2/2)  Wholemount images
Peripheral nervous system 2 No  (1/590) N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/590)  (1/2)  Wholemount images
Prostate gland 2 No  (12/590) N/A
Skeletal muscle 2 No  (1/2)  Wholemount images
Skin 2 No N/A
Small intestine 2 No  (9/590) N/A
Spinal cord 2 No  (2/590)  (2/2)  Wholemount images
Spleen 2 No  (2/590) N/A
Stomach 2 No  (13/590)  (2/2)  Wholemount images
Striatum 2 No  (3/590)  (2/2)  Wholemount images
Testis 2 No  (5/590)  (1/2)  Wholemount images
Thymus 2 No N/A
Thyroid gland 2 No  (16/590)  (2/2)  Wholemount images
Trachea 2 No  (2/590) N/A
Uterus 2 No N/A
Vascular system 2 No  (1/2)  Wholemount images
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/506)  (1/4) N/A
Ear 2  (1/506) N/A
Embryo 2  (1/507)  (4/4) N/A
Eye 2  (1/506)  (2/4) N/A
Foot 2  (1/506) N/A
Forebrain 2  (1/506) N/A
Forelimb 2  (1/506) N/A
Hand 2  (1/506) N/A
Head 2  (5/506)  (2/4) N/A
Heart 2  (1/506)  (1/4) N/A
Hindbrain 2  (6/506)  (1/4) N/A
Hindlimb 2  (1/506) N/A
Liver 2  (1/504) N/A
Lung 2  (1/504) N/A
Mandibular process 2  (1/506) N/A
Maxillary process 2  (1/506) N/A
Midbrain 2  (1/506) N/A
Oral cavity 2  (1/504) N/A
Skin 2  (1/506) N/A
Tail 2  (1/506) N/A
Tail somite 2  (1/506) N/A

 Associated Images

X-ray: XRay Images Whole Body Lateral Orientation
9 Images
Adult LacZ: LacZ Images Wholemount
14 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
9 Images
X-ray: XRay Images Whole Body Dorso Ventral
9 Images
Embryo LacZ: LacZ images wholemount
8 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Kcnj11tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice
Kcnj11tm1c(EUCOMM)Wtsi Wild type floxed exon (post-Flp) Mice
Kcnj11em1H Point Mutation Mice
Kcnj11tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells

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