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Gene: Pxmp2 MGI:107487

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Not currently registered for phenotyping at IMPC

Phenotyping is currently not planned for a knockout strain of this gene.

Gene Summary

Name:
peroxisomal membrane protein 2
Synonyms:
PMP22,  22kDa

Order Alleles

IMPC Data Collections

  • No Body Weight Data
  • No Embryo Imaging Data
  • No Viability Data

IMPC Phenotype Summary

Significant
Not Significant
Not tested

View all our phenotype data below

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Phenotype associated images not available

Human diseases caused by Pxmp2 mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

No human diseases associated to this gene by orthology or annotation.

The table below shows human diseases predicted to be associated to Pxmp2 by phenotypic similarity.

Disease Similarity of
phenotypes		 Matching phenotypes Source
Glomerulocystic kidney disease with hyperuricemia and isosthenuria
Abnormal renal tubule morphology, Renal insufficiency, Hyperuricemia, Multiple glomerular cysts OMIM:609886
Tubulointerstitial Kidney Disease, Autosomal Dominant, 4
Renal tubular atrophy, Hyperuricemia, Hyperechogenic kidneys, Renal hypoplasia, Proteinuria, Foca... OMIM:613092
Mild Phosphoribosylpyrophosphate Synthetase Superactivity
Increased phosphoribosylpyrophosphate synthetase level, Uric acid nephrolithiasis, Crystalluria, ... ORPHA:411536
Xanthinuria, Type Ii
Hyperxanthinemia, Increased urinary hypoxanthine, Hypouricemia, Xanthinuria, Renal insufficiency,... OMIM:603592
Tubulointerstitial Kidney Disease, Autosomal Dominant, 1
Renal tubular atrophy, Hyperuricemia, Nephritis, Nephropathy, Decreased glomerular filtration rat... OMIM:162000
Glycogen Storage Disease V
Myoglobinuria, Dark urine, Hyperuricemia, Elevated circulating creatine kinase concentration OMIM:232600
Lesch-Nyhan Syndrome
Renal insufficiency, Hyperuricemia, Hematuria ORPHA:510
Glycine N-Methyltransferase Deficiency
Hypermethioninemia, Elevated hepatic transaminase, Hepatomegaly OMIM:606664
Glycogen Storage Disease Ixa1
Hyperuricemia, Elevated hepatic transaminase, Hepatomegaly, Hypercholesterolemia, Hypertriglyceri... OMIM:306000
Hereditary Xanthinuria
Uric acid nephrolithiasis, Sulfite oxidase deficiency, Crystalluria, Recurrent urinary tract infe... ORPHA:3467
Glycogen Storage Disease Vii
Increased total bilirubin, Hyperuricemia, Exercise-induced myoglobinuria, Jaundice, Cholelithiasis OMIM:232800
Burkitt Lymphoma
Increased circulating lactate dehydrogenase concentration, Abnormality of the ovary, Abnormality ... ORPHA:543
Renal Cysts And Diabetes Syndrome
Abnormality of alkaline phosphatase level, Elevated hepatic transaminase, Biliary tract abnormali... OMIM:137920
Tubulointerstitial Kidney Disease, Autosomal Dominant, 5
Hyperuricemia, Renal cyst, Nephropathy, Elevated circulating creatinine concentration, Focal segm... OMIM:617056
3-Hydroxy-3-Methylglutaryl-Coa Lyase Deficiency
Hyperuricemia, Decreased plasma carnitine, Increased level of 3-hydroxy-3-methylglutaric acid in ... OMIM:246450
Nephropathy, Progressive Tubulointerstitial, With Cholestatic Liver Disease
Elevated hepatic transaminase, Abnormal tubulointerstitial morphology, Nephropathy, Cholestatic l... OMIM:602114
Hypoxanthine Guanine Phosphoribosyltransferase Partial Deficiency
Uric acid nephrolithiasis, Hyperuricemia, Acute kidney injury, Dysuria, Nephropathy, Macroscopic ... ORPHA:79233
Hnf1B-Related Autosomal Dominant Tubulointerstitial Kidney Disease
Glomerulopathy, Hypothyroidism, Multicystic kidney dysplasia, Hyperuricemia, Aplasia/Hypoplasia o... ORPHA:93111
Severe Phosphoribosylpyrophosphate Synthetase Superactivity
Increased phosphoribosylpyrophosphate synthetase level, Uric acid nephrolithiasis, Crystalluria, ... ORPHA:411543
Hyperuricemia, Hprt-Related
Renal insufficiency, Hyperuricemia, Nephrolithiasis, Hyperuricosuria OMIM:300323
Lipodystrophy, Familial Partial, Type 3
Cirrhosis, Hyperuricemia, Oligomenorrhea, Hepatic steatosis, Polycystic ovaries, Hirsutism, Decre... OMIM:604367
Cystinuria
Renal insufficiency, Hyperuricemia, Hematuria, Nephrolithiasis ORPHA:214
Hypomagnesemia 3, Renal
Hyperuricemia, Hypocitraturia, Hypercitraturia, Recurrent urinary tract infections, Hypermagnesiu... OMIM:248250
Distal 16P11.2 Microdeletion Syndrome
Vesicoureteral reflux, Hyperuricemia, Abnormality of the kidney, Renal agenesis, Proteinuria, Low... ORPHA:261222
Medullary cystic kidney disease 2
Renal tubular atrophy, Tubulointerstitial nephritis, Multiple small medullary renal cysts, Hyperu... OMIM:603860
Hypouricemia, Renal, 1
Renal cortical hyperechogenicity, Urolithiasis, Uric acid nephrolithiasis, Acute kidney injury, R... OMIM:220150
Lactic Acidosis, Chronic Adult Form
Hyperuricemia OMIM:150170
Hereditary Renal Hypouricemia
Acute kidney injury, Abnormal renal tubule morphology, Hematuria, Abnormal renal physiology, Hype... ORPHA:94088
Glycogen Storage Disease Ixb
Increased hepatic glycogen content, Hyperuricemia, Hepatomegaly OMIM:261750
Alstrom Syndrome
Tubulointerstitial nephritis, Alopecia, Irregular menstruation, Hyperuricemia, Decreased response... OMIM:203800
Fanconi Renotubular Syndrome 4 With Maturity-Onset Diabetes Of The Young
Aminoaciduria, Glycosuria, Hyperphosphaturia, Hypophosphatemia, Elevated hepatic transaminase, El... OMIM:616026
Hyperuricemia, Pulmonary Hypertension, Renal Failure, And Alkalosis Syndrome
Hyperuricemia, Renal salt wasting, Increased blood urea nitrogen, Polyuria, Hyponatremia, Protein... OMIM:613845
Pparg-Related Familial Partial Lipodystrophy
Cirrhosis, Hyperuricemia, Secondary amenorrhea, Oligomenorrhea, Hepatic steatosis, Polycystic ova... ORPHA:79083
Hyperuricemic Nephropathy, Familial Juvenile, 3
Impaired renal concentrating ability, Abnormal renal insterstitial morphology, Renal insufficienc... OMIM:614227
Tubulointerstitial Kidney Disease, Autosomal Dominant, 2
Renal tubular atrophy, Tubulointerstitial nephritis, Hyperuricemia, Stage 5 chronic kidney diseas... OMIM:174000
Interstitial Nephritis, Karyomegalic
Tubulointerstitial nephritis, Renal interstitial fibrosis, Renal tubular cyst, Glycosuria, Stage ... OMIM:614817
Lesch-Nyhan Phenotype With Normal Hgprt
Hyperuricemia OMIM:308950
Phosphoribosylpyrophosphate Synthetase Superactivity
Renal insufficiency, Hyperuricemia ORPHA:3222
Hereditary Fructose Intolerance
Reduced circulating aldolase concentration, Hyperuricemia, Jaundice, Hypophosphatemia, Chronic he... ORPHA:469
Glycogen Storage Disease Due To Muscle Phosphofructokinase Deficiency
Hyperuricemia ORPHA:371
Glycogen Storage Disease Due To Glucose-6-Phosphatase Deficiency
Hyperuricemia, Hyperlipidemia ORPHA:364
Glycogen Storage Disease Ia
Hyperuricemia, Enlarged kidney, Elevated hepatic transaminase, Hepatocellular carcinoma, Decrease... OMIM:232200
Fructose-1,6-Bisphosphatase Deficiency
Hyperuricemia, Hyperalaninemia, Elevated hepatic transaminase, Abnormal circulating enzyme concen... ORPHA:348
Fructose Intolerance, Hereditary
Transient aminoaciduria, Cirrhosis, Proximal tubulopathy, Hyperuricemia, Glycosuria, Jaundice, Hy... OMIM:229600
Glycogen Storage Disease Ib
Hyperuricemia, Enlarged kidney, Elevated hepatic transaminase, Hepatocellular carcinoma, Decrease... OMIM:232220
Cholestasis, Progressive Familial Intrahepatic, 12
Elevated circulating alanine aminotransferase concentration, Jaundice, Hyperbilirubinemia, Elevat... OMIM:620010
Hypouricemia, Hypercalcinuria, And Decreased Bone Density
Hypercalciuria, Hypouricemia OMIM:242050
Galactosemia I
Aminoaciduria, Elevated circulating alanine aminotransferase concentration, Cirrhosis, Increased ... OMIM:230400
Molybdenum Cofactor Deficiency, Complementation Group A
Sulfite oxidase deficiency, Increased urinary taurine, Increased urinary thiosulfate, Reduced xan... OMIM:252150
Combined Deficiency Of Factor V And Factor Viii
Menorrhagia, Hyperuricemia, Hematuria, Hyperlipidemia ORPHA:35909
Morgagni-Stewart-Morel Syndrome
Hypothyroidism, Hyperuricemia, Hirsutism, Hypercholesterolemia ORPHA:77296
Paget Disease Of Bone 5, Juvenile-Onset
Hyperphosphatemia, Hyperuricemia, Hydroxyprolinuria, Elevated circulating alkaline phosphatase co... OMIM:239000
Fanconi-Bickel Syndrome
Glycosuria, Hyperphosphaturia, Hypophosphatemia, Hypokalemia, Generalized aminoaciduria, Elevated... OMIM:227810
Juvenile Nephropathic Cystinosis
Abnormal urine potassium concentration, Aminoaciduria, Hypocalcemic tetany, Hypothyroidism, Low-m... ORPHA:411634
Congenital Disorder Of Glycosylation, Type Iip
Decreased circulating ceruloplasmin concentration, Elevated hepatic transaminase, Hepatic steatos... OMIM:616829
Hyperuricemia, Infantile, With Abnormal Behavior And Normal Hypoxanthine Guanine Phosphoribosyltransferase
Hyperuricemia OMIM:240000
Dent Disease 2
Aminoaciduria, Elevated circulating alanine aminotransferase concentration, Proximal tubulopathy,... OMIM:300555
Neuroleptic Malignant Syndrome
Urinary incontinence, Hyperphosphatemia, Hyperuricemia, Hyperhidrosis, Acute kidney injury, Hyper... ORPHA:94093
Phosphoribosylpyrophosphate Synthetase Superactivity
Increased phosphoribosylpyrophosphate synthetase level, Urolithiasis, Uric acid nephrolithiasis, ... OMIM:300661
Glycogen Storage Disease Due To Glucose-6-Phosphatase Deficiency Type Ib
Hypothyroidism, Hepatocellular carcinoma, Hepatic steatosis, Hepatomegaly, Hypercholesterolemia, ... ORPHA:79259
Gilbert Syndrome
Unconjugated hyperbilirubinemia, Jaundice, Hepatic failure, Elevated hepatic transaminase OMIM:143500
Lesch-Nyhan Syndrome
Hyperuricemia, Testicular atrophy, Nephrocalcinosis, Nephrolithiasis, Hyperuricosuria OMIM:300322
Hypouricemia, Renal, 2
Nephrolithiasis, Hypouricemia OMIM:612076
Molybdenum Cofactor Deficiency, Complementation Group C
Sulfite oxidase deficiency, Increased urinary taurine, Hypertaurinemia, Molybdenum cofactor defic... OMIM:615501
3-Hydroxy-3-Methylglutaric Aciduria
Hyperuricemia, Ketonuria, Jaundice, Elevated hepatic transaminase, Acute pancreatitis, Hyperammon... ORPHA:20
Primary Fanconi Renotubular Syndrome
Renal phosphate wasting, Hyperuricosuria, Stage 5 chronic kidney disease, Renal sodium wasting, G... ORPHA:3337
Glycogen Storage Disease Vi
Hypercholesterolemia, Elevated hepatic transaminase, Increased hepatic glycogen content, Hyperlip... OMIM:232700
Late-Onset Isolated Acth Deficiency
Hyperuricemia, Hepatitis, Premature ovarian insufficiency, Decreased circulating cortisol level, ... ORPHA:199299
Hemochromatosis, Type 2B
Hepatic fibrosis, Cirrhosis, Hypogonadism, Secondary amenorrhea, Elevated transferrin saturation,... OMIM:613313
Acute Adrenal Insufficiency
Hyperuricemia, Decreased circulating aldosterone level, Decreased female libido, Sparse axillary ... ORPHA:95409
Wilson Disease
Aminoaciduria, Hyperphosphaturia, Decreased circulating ceruloplasmin concentration, Hepatocellul... OMIM:277900
Juvenile Paget Disease
Hyperuricemia ORPHA:2801
Preeclampsia
Acute kidney injury, Abnormality of the kidney, Elevated hepatic transaminase, Polycystic ovaries... ORPHA:275555
Addison Disease
Hyperuricemia, Primary testicular failure, Decreased circulating aldosterone level, Decreased fem... ORPHA:85138
Glycogen Storage Disease Ic
Hyperuricemia, Chronic pancreatitis, Hepatocellular carcinoma, Hematuria, Hepatoblastoma, Decreas... OMIM:232240
Citrullinemia, Type Ii, Adult-Onset
Elevated circulating alanine aminotransferase concentration, Hepatic fibrosis, Argininosuccinic a... OMIM:603471
Beta-Ketothiolase Deficiency
Hyperammonemia, Hyperuricemia, Hepatomegaly, Ketonuria ORPHA:134
Hemochromatosis Type 2
Abnormality of iron homeostasis, Impotence, Hypogonadism, Abnormality of endocrine pancreas physi... ORPHA:79230
Hypertriglyceridemia, Transient Infantile
Hepatic fibrosis, Elevated hepatic transaminase, Hepatic steatosis, Elevated gamma-glutamyltransf... OMIM:614480
Cholestasis, Intrahepatic, Of Pregnancy, 1
Jaundice, Elevated hepatic transaminase, Intrahepatic cholestasis, Increased serum bile acid conc... OMIM:147480
Xanthinuria, Type I
Reduced xanthine dehydrogenase level, Pyelonephritis, Xanthine nephrolithiasis, Hyperxanthinemia,... OMIM:278300
Bile Acid Synthesis Defect, Congenital, 5
Hepatic failure, Hepatic fibrosis, Increased total iron binding capacity, Jaundice, Hyperbilirubi... OMIM:616278
Cholestasis-Lymphedema Syndrome
Cirrhosis, Jaundice, Elevated hepatic transaminase, Elevated circulating alkaline phosphatase con... OMIM:214900
Molybdenum Cofactor Deficiency, Complementation Group B
Increased urinary taurine, Xanthine nephrolithiasis, Increased urinary hypoxanthine, Increased ur... OMIM:252160
Mitochondrial Complex Iii Deficiency, Nuclear Type 5
Hyperalaninemia, Elevated circulating sebacic acid concentration, Elevated circulating suberic ac... OMIM:615160
Biliary Atresia, Extrahepatic
Increased total bilirubin, Atretic gallbladder, Cirrhosis, Extrahepatic biliary duct atresia, Unc... OMIM:210500
Carnitine Palmitoyltransferase I Deficiency
Elevated circulating alanine aminotransferase concentration, Renal tubular acidosis, Elevated hep... OMIM:255120
Congenital Bile Acid Synthesis Defect Type 2
Hepatic failure, Jaundice, Abnormal serum bile acid concentration, Elevated hepatic transaminase,... ORPHA:79303
Bile Acid Conjugation Defect 1
Elevated circulating alanine aminotransferase concentration, Hepatic failure, Jaundice, Elevated ... OMIM:619232
Hemochromatosis, Type 3
Cirrhosis, Impotence, Elevated transferrin saturation, Elevated hepatic transaminase, Increased c... OMIM:604250
Hypouricemia, Familial Renal, Due To Tubular Hypersecretion
Hypouricemia OMIM:307830
Hepatorenocardiac Degenerative Fibrosis
Cirrhosis, Renal interstitial fibrosis, Enlarged kidney, Jaundice, Elevated hepatic transaminase,... OMIM:619902
Cholestasis, Progressive Familial Intrahepatic, 8
Hepatic fibrosis, Elevated circulating alanine aminotransferase concentration, Cirrhosis, Scleros... OMIM:619662
Gaisböck Syndrome
Hyperuricemia, Hypernatriuria, Increased circulating renin level, Cholecystitis, Hypercholesterol... ORPHA:90041
Blue Diaper Syndrome
Hyperphosphatemia, Elevated circulating thyroid-stimulating hormone concentration, Elevated hepat... ORPHA:94086
Cockayne Syndrome
Urinary incontinence, Dry hair, Hyperuricemia, Nephrotic syndrome, Neurogenic bladder, Anhidrosis... ORPHA:191
Protoporphyria, Erythropoietic, X-Linked
Increased erythrocyte protoporphyrin concentration, Elevated hepatic transaminase, Cholelithiasis OMIM:300752
Citrullinemia, Type Ii, Neonatal-Onset
Hyperlysinemia, Hyperargininemia, Hypercholesterolemia, Conjugated hyperbilirubinemia, Hyperthreo... OMIM:605814
Liver Failure, Infantile, Transient
3-hydroxydicarboxylic aciduria, Elevated circulating alanine aminotransferase concentration, Micr... OMIM:613070
Tyrosinemia, Type Iii
Hypertyrosinemia, 4-hydroxyphenylacetic aciduria, 4-Hydroxyphenylpyruvic aciduria, Elevated hepat... OMIM:276710
Neonatal Intrahepatic Cholestasis Due To Citrin Deficiency
Hyperlysinemia, Abnormal circulating lipid concentration, Hypergalactosemia, Elevated hepatic tra... ORPHA:247598
Congenital Bile Acid Synthesis Defect Type 3
Elevated circulating alanine aminotransferase concentration, Hepatic failure, Cirrhosis, Jaundice... ORPHA:79302
Arthrogryposis, Renal Dysfunction, And Cholestasis 2
Aminoaciduria, Renal tubular acidosis, Glycosuria, Jaundice, Elevated hepatic transaminase, Nephr... OMIM:613404
Gallbladder Disease 1
Hepatic fibrosis, Cholesterol gallstones, Jaundice, Pancreatitis, Elevated hepatic transaminase, ... OMIM:600803
Porphyria Cutanea Tarda
Abnormal circulating porphyrin concentration, Porphyrinuria, Periportal fibrosis, Decreased circu... ORPHA:101330
Cholestasis, Progressive Familial Intrahepatic, 3
Cirrhosis, Jaundice, Elevated hepatic transaminase, Portal inflammation, Portal fibrosis, Intrahe... OMIM:602347
Genetic Recurrent Myoglobinuria
Hyperphosphatemia, Acute kidney injury, Exercise-induced myoglobinuria, Highly elevated creatine ... ORPHA:99845
Cholestasis, Progressive Familial Intrahepatic, 6
Periportal fibrosis, Elevated hepatic transaminase, Intrahepatic cholestasis, Elevated circulatin... OMIM:619484
Mitochondrial Complex Iv Deficiency, Nuclear Type 22
3-hydroxydicarboxylic aciduria, Hepatic failure, Hyperalaninemia, Ketonuria, Increased urine alph... OMIM:619355
Glycogen Storage Disease Due To Phosphorylase Kinase Deficiency
Hypercholesterolemia, Irregular menstruation, Hepatic fibrosis, Cirrhosis, Hypertriglyceridemia, ... ORPHA:370
Bile Acid Synthesis Defect, Congenital, 2
Hepatic failure, Jaundice, Hyperbilirubinemia, Elevated hepatic transaminase, Intrahepatic choles... OMIM:235555
Isolated Biliary Atresia
Atretic gallbladder, Cirrhosis, Hypothyroidism, Periportal fibrosis, Dark yellow urine, Jaundice,... ORPHA:30391
Bile Acid Synthesis Defect, Congenital, 4
Hepatic failure, Hyperbilirubinemia, Elevated hepatic transaminase, Decreased serum bile acid con... OMIM:214950
Purine Nucleoside Phosphorylase Deficiency
Increased circulating guanosine concentration, Increased circulating inosine concentration, Hypou... OMIM:613179
Purine Nucleoside Phosphorylase Deficiency
Decreased urinary urate, Hypouricemia ORPHA:760
Bile Acid Synthesis Defect, Congenital, 1
Hepatic failure, Cirrhosis, Jaundice, Elevated hepatic transaminase, Acholic stools, Intrahepatic... OMIM:607765
Glycogen Storage Disease Due To Hepatic Glycogen Synthase Deficiency
Glycosuria, Elevated hepatic transaminase, Hyperlipidemia, Ketonuria ORPHA:2089
Familial Osteodysplasia, Anderson Type
Thick eyebrow, Hyperuricemia ORPHA:2769
Alport Syndrome 3, Autosomal Dominant
Glomerular basement membrane lamellation, Nephrotic syndrome, Stage 5 chronic kidney disease, Azo... OMIM:104200
Low Phospholipid-Associated Cholelithiasis
Biliary cirrhosis, Liver abscess, Neoplasm of the liver, Sclerosing cholangitis, Hepatocellular c... ORPHA:69663
Lethal Ataxia With Deafness And Optic Atrophy
Abnormal erythrocyte enzyme level, Hypouricemia ORPHA:1187
Senior-Boichis Syndrome
Abnormal renal insterstitial morphology, Elevated hepatic transaminase, Malformation of the hepat... ORPHA:84081
Parenteral Nutrition-Associated Cholestasis
Hepatic fibrosis, Biliary hyperplasia, Cirrhosis, Hepatic failure, Jaundice, Elevated hepatic tra... ORPHA:567983
Primary Hyperoxaluria Type 3
Pollakisuria, Calcium oxalate nephrolithiasis, Dysuria, Abnormality of urine homeostasis, Hematur... ORPHA:93600
Mitochondrial Dna Depletion Syndrome 15 (Hepatocerebral Type)
Hypermethioninemia, Hepatic failure, Cirrhosis, Microvesicular hepatic steatosis, Jaundice, 4-hyd... OMIM:617156
Severe Congenital Hypochromic Anemia With Ringed Sideroblasts
Hypothyroidism, Hypogonadism, Adrenal insufficiency, Decreased transferrin saturation, Azoospermi... ORPHA:300298
Ornithine Transcarbamylase Deficiency, Hyperammonemia Due To
Elevated circulating alanine aminotransferase concentration, Elevated circulating uracil concentr... OMIM:311250
Lysinuric Protein Intolerance
Hyperlysinuria, Ornithinuria, Elevated hepatic transaminase, Hepatosplenomegaly, Glomerulonephrit... ORPHA:470
Mirizzi Syndrome
Cholesterol gallstones, Jaundice, Hyperbilirubinemia, Elevated hepatic transaminase, Pancreatitis... ORPHA:521219
Eisenmenger Syndrome
Hyperuricemia, Abnormality of the liver, Abnormal B-type natriuretic peptide concentration, Eleva... ORPHA:97214
Caroli Syndrome
Cirrhosis, Hepatic failure, Periportal fibrosis, Liver abscess, Abnormality of the kidney, Jaundi... ORPHA:480520
Tyrosinemia, Type I
Hypermethioninemia, Cirrhosis, Hepatic failure, Renal Fanconi syndrome, Enlarged kidney, Elevated... OMIM:276700

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Pxmp2

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Pxmp2.

No publications found that use IMPC mice or data for Pxmp2.

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MGI Allele Allele Type Produced
Pxmp2tm1e(EUCOMM)Hmgu Targeted, non-conditional allele ES Cells
Pxmp2tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

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