Gene: Tbr1

Name
T-box brain gene 1
MGI ID
MGI:107404
Synonyms
N/A
Viability
Homozygous - Subviable
Other links
View data by physiological system
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
increased prepulse inhibition Tbr1tm1b(KOMP)Mbp HET postnatal 9.14×10-06
decreased blood urea nitrogen level Tbr1tm1b(KOMP)Mbp HET postnatal 9.87×10-06
decreased circulating glucose level Tbr1tm1b(KOMP)Mbp HET postnatal 2.37×10-08
preweaning lethality, incomplete penetrance Tbr1tm1b(KOMP)Mbp HOM n/a 0.00

Download data as:  TSV  XLS

Filtered by: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584) N/A
Aorta 2 No N/A
Blood 2 No N/A
Bone marrow 2 No N/A
Brain 2 No N/A
Brainstem 2 No N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No N/A
Cecum 2 No  (12/383) N/A
Cerebellum 2 No N/A
Cerebral cortex 2 No N/A
Chest bone 2 No N/A
Colon 2 No  (12/127) N/A
Diaphragm 2 No N/A
Duodenum 2 No  (2/127) N/A
Epididymis 2 No  (18/134)  (1/2) N/A
Esophagus 2 No  (7/415) N/A
Eye 2 No N/A
Gall bladder 2 No N/A
Gonadal fat pad 2 No N/A
Harderian gland 2 No N/A
Heart 2 No N/A
Hindlimb 2 No N/A
Hippocampus 2 No N/A
Hypothalamus 2 No N/A
Ileum 2 No  (14/127) N/A
Jejunum 2 No  (6/127) N/A
Kidney 2 No  (18/584) N/A
Large intestine 2 No  (10/584) N/A
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No N/A
Lymph node 2 No N/A
Mammary gland 2 No N/A
Mesenteric adipose tissue 2 No N/A
Mesenteric lymph node 2 No N/A
Midbrain 2 No  (2/2) N/A
Olfactory lobe 2 No  (2/2) N/A
Ovary 2 No  (1/584) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/584) N/A
Parathyroid gland 2 No N/A
Parotid gland 2 No N/A
Penis 2 No N/A
Peripheral nervous system 2 No N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No N/A
Prostate gland 2 No  (12/584)  (1/2) N/A
Quadriceps 2 No N/A
Sciatic nerve 2 No N/A
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584) N/A
Spinal cord 2 No N/A
Spleen 2 No  (2/584) N/A
Stomach 2 No  (12/584) N/A
Stomach pyloric region 2 No N/A
Striatum 2 No N/A
Sublingual gland 2 No N/A
Submandibular gland 2 No  (2/132) N/A
Testis 2 No  (2/584)  (1/2) N/A
Thymus 2 No N/A
Thyroid gland 2 No  (15/584) N/A
Tongue 2 No  (5/127) N/A
Trachea 2 No N/A
Trigeminal V nerve 2 No N/A
Urinary bladder 2 No N/A
Uterus 2 No N/A
Vagina 2 No N/A
Vas deferens 2 No  (15/388)  (1/2) N/A
Vascular system 2 No N/A
Vesicular gland 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Axial skeleton 3  (1/51) N/A
Brain 3  (6/485)  (6/6) N/A
Central nervous system ganglion 3  (1/51) N/A
Dorsal root ganglion 3  (1/47) N/A
Ear 3  (1/485) N/A
Embryo 3  (1/485)  (6/6) N/A
Eye 3  (1/485) N/A
Foot 3  (1/485) N/A
Forebrain 3  (1/485)  (6/6) N/A
Forelimb 3  (1/485) N/A
Fronto-nasal process 3  (1/48) N/A
Gut 3  (1/50)  (1/6) N/A
Hand 3  (1/485) N/A
Head 3  (5/485) N/A
Head mesenchyme 3  (1/47) N/A
Heart 3  (1/485) N/A
Hindbrain 3  (6/485) N/A
Hindlimb 3  (1/485) N/A
Liver 3  (1/485) N/A
Lung 3  (1/485) N/A
Mandibular process 3  (1/485) N/A
Maxillary process 3  (1/485)  (1/6) N/A
Midbrain 3  (1/485) N/A
Nasal septum 3  (1/47) N/A
Nose 3  (1/51) N/A
Notochord 3  (1/47) N/A
Oral cavity 3  (1/485) N/A
Skeleton 3  (1/51) N/A
Skin 3  (1/485) N/A
Spinal cord 3  (1/50) N/A
Tail 3  (1/485) N/A
Tail somite 3  (1/485)  (1/6) N/A
Trunk mesenchyme 3  (1/47) N/A
Vibrissa 3  (1/47) N/A

 Associated Images

X-ray: XRay Images Dorso Ventral
11 Images
X-ray: XRay Images Lateral Orientation
11 Images

 Disease Models

Please visit the desktop version to see this section

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Tbr1tm1b(KOMP)Mbp Reporter-tagged deletion allele (post-Cre) Mice, Tissue
Tbr1tm1(KOMP)Mbp Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells
Tbr1tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Targeting vectors, ES Cells

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter