Gene: Dnm1

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Phenotype System Allele Zyg Sex Life Stage P Value
abnormal bone structure Dnm1tm1.1(KOMP)Vlcg HET   Early adult 6.42×10-06
preweaning lethality, complete penetrance Dnm1tm1.1(KOMP)Vlcg HOM   Early adult 0.00

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Select physiological systems to view:
Viewing: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (4/583) N/A
Aorta 2 No  (1/583) N/A
Blood 2 No N/A
Bone marrow 2 No N/A
Brain 2 No  (4/583) N/A
Brainstem 2 No  (2/583) N/A
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (1/583) N/A
Cecum 2 No  (12/371) N/A
Cerebellum 2 No  (3/583) N/A
Cerebral cortex 2 No  (2/583) N/A
Chest bone 2 No N/A
Colon 2 No  (12/127) N/A
Diaphragm 2 No N/A
Duodenum 2 No  (2/127) N/A
Epididymis 2 No  (18/132)  (1/2)  Section images
Esophagus 2 No  (7/407) N/A
Eye 2 No  Section images
Gall bladder 2 No N/A
Gonadal fat pad 2 No N/A
Harderian gland 2 No N/A
Heart 2 No  (2/583) N/A
Hindlimb 2 No N/A
Hippocampus 2 No  (3/583) N/A
Hypothalamus 2 No  (2/583) N/A
Ileum 2 No  (14/127)  (1/2)  Section images
Jejunum 2 No  (6/127) N/A
Kidney 2 No  (21/583)  (2/2)  Section images
Large intestine 2 No  (10/583) N/A
Liver 2 No N/A
Lower urinary tract 2 No  (1/583) N/A
Lung 2 No  (2/583) N/A
Lymph node 2 No  (1/583) N/A
Mammary gland 2 No N/A
Mesenteric adipose tissue 2 No N/A
Mesenteric lymph node 2 No N/A
Midbrain 2 No  (2/2)  Section images
Olfactory lobe 2 No  (2/583)  (2/2)  Section images
Ovary 2 No  (1/583) N/A
Oviduct 2 No N/A
Pancreas 2 No  (5/583) N/A
Parathyroid gland 2 No  (1/563) N/A
Parotid gland 2 No N/A
Penis 2 No  (1/2)  Section images
Peripheral nervous system 2 No  (2/583) N/A
Peyer's patch 2 No N/A
Pituitary gland 2 No  (1/583) N/A
Prostate gland 2 No  (12/583) N/A
Quadriceps 2 No N/A
Sciatic nerve 2 No N/A
Skeletal muscle 2 No N/A
Skin 2 No  (1/583) N/A
Small intestine 2 No  (9/583) N/A
Spinal cord 2 No  (3/583)  (2/2)  Section images
Spleen 2 No  (3/583) N/A
Stomach 2 No  (13/583) N/A
Stomach pyloric region 2 No N/A
Striatum 2 No  (3/583) N/A
Sublingual gland 2 No N/A
Submandibular gland 2 No  (2/130) N/A
Testis 2 No  (6/583)  (1/2)  Section images
Thymus 2 No  (1/583) N/A
Thyroid gland 2 No  (17/583) N/A
Tongue 2 No  (5/127) N/A
Trachea 2 No  (3/583) N/A
Trigeminal V nerve 2 No N/A
Urinary bladder 2 No N/A
Uterus 2 No N/A
Vagina 2 No N/A
Vas deferens 2 No  (15/382)  (1/2)  Section images
Vascular system 2 No N/A
Vesicular gland 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
2  (1/60) N/A
2  (1/64)  (7/7) N/A
2  (6/505) N/A
2  (1/73)  (4/7) N/A
2  (1/60)  (7/7) N/A
2  (1/505) N/A
2  (1/506)  (7/7) N/A
1  (1/71) N/A
2  (1/505) N/A
2  (1/55)  (4/7) N/A
2  (1/505) N/A
2  (1/302)  (7/7) N/A
2  (1/505) N/A
2  (1/505)  (6/7) N/A
2  (1/61)  (4/7) N/A
2  (1/505) N/A
2  (5/505)  (7/7) N/A
2  (1/60)  (7/7) N/A
2  (1/505) N/A
2  (1/60) N/A
2  (6/505) N/A
2  (1/505)  (7/7) N/A
1  (1/64) N/A
2  (1/58) N/A
2  (1/503) N/A
2  (1/302)  (7/7) N/A
2  (1/503) N/A
2  (1/505)  (3/7) N/A
2  (1/505)  (3/7) N/A
2  (3/7) N/A
2  (1/505) N/A
2  (1/60)  (3/6) N/A
2  (1/75) N/A
2  (1/60) N/A
2  (1/503)  (4/7) N/A
2  (1/60) N/A
2  (1/55) N/A
2  (1/56) N/A
2  (7/39) N/A
2  (1/64)  (7/7) N/A
0  (1/57)  (4/4) N/A
2  (1/75)  (1/7) N/A
2  (1/505) N/A
2  (1/72) N/A
2  (1/505) N/A
2  (1/505) N/A
0  (1/55)  (4/4) N/A
2  (1/55)  (3/7) N/A
2  (1/60) N/A
2  (1/60) N/A
2  (1/60) N/A
2  (1/302) N/A
2  (1/302) N/A
2  (1/71) N/A

 Associated Images

X-ray: XRay Images Whole Body Lateral Orientation
10 Images
Adult LacZ: LacZ Images Section
30 Images
X-ray: XRay Images Whole Body Dorso Ventral
10 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Dnm1tm51066(L1L2_Bact_P) Targeting vectors
Dnm1tm1.1(KOMP)Vlcg Reporter-tagged deletion allele (post Cre, with no selection cassette) Mice, Tissue
Dnm1tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Mice, Targeting vectors, ES Cells

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