Gene: Stxbp1

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Name
syntaxin binding protein 1
MGI ID
MGI:107363
Synonyms
Munc-18a Sxtbp1 Munc18-1 Unc18h Rb-sec1 N-sec1 nsec1
Viability
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
hyperactivity Stxbp1tm1b(EUCOMM)Hmgu HET Early adult 5.81×10-06
increased bone mineral content Stxbp1tm1b(EUCOMM)Hmgu HET Early adult 6.17×10-05
hypoactivity Stxbp1tm1b(EUCOMM)Hmgu HET Early adult 1.41×10-05
increased thigmotaxis Stxbp1tm1b(EUCOMM)Hmgu HET Early adult 1.93×10-11
abnormal behavior Stxbp1tm1b(EUCOMM)Hmgu HET Early adult 4.57×10-11
preweaning lethality, complete penetrance Stxbp1tm1b(EUCOMM)Hmgu HOM   Early adult 0.00

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 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
2 No  (4/583)  (2/2)  Section images
2 No  (1/583)  (2/2)  Section images
2 No  (4/583)  (2/2)  Section images
2 No  (2/583)  (2/2)  Section images
2 No N/A
2 No  (1/583)  (2/2)  Section images
2 No  (3/583)  (2/2)  Section images
2 No  (2/583)  (2/2)  Section images
2 No  (18/132)  (1/2)  Section images
2 No  (7/407)  (2/2)  Section images
2 No  (2/2)  Section images
2 No  (2/583)  (2/2)  Section images
2 No  (3/583)  (2/2)  Section images
2 No  (2/583)  (2/2)  Section images
2 No  (21/583)  (2/2)  Section images
2 No  (10/583)  (2/2)  Section images
2 No N/A
2 No  (1/583) N/A
2 No  (2/583)  (2/2)  Section images
2 No  (1/583) N/A
2 No  (1/2)  Section images
2 No  (2/2)  Section images
2 No  (2/583)  (2/2)  Section images
2 No  (1/583)  (1/2)  Section images
2 No  (1/2)  Section images
2 No  (5/583)  (2/2)  Section images
2 No  (2/583)  (2/2)  Section images
2 No N/A
2 No  (1/583)  (2/2)  Section images
2 No  (12/583) N/A
2 No N/A
2 No  (1/583) N/A
2 No  (9/583)  (2/2)  Section images
2 No  (3/583)  (2/2)  Section images
2 No  (3/583)  (2/2)  Section images
2 No  (13/583)  (2/2)  Section images
2 No  (3/583)  (2/2)  Section images
2 No  (2/130)  (1/2)  Section images
2 No  (6/583)  (1/2)  Section images
2 No  (2/2)  Section images
2 No  (1/583)  (2/2)  Section images
2 No  (17/583)  (2/2)  Section images
2 No  (3/583) N/A
2 No  (2/2)  Section images
2 No  (1/2)  Section images
2 No  (2/2)  Section images
2 No N/A
2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
2  (6/505)  (2/3) N/A
2  (1/73)  (2/2) N/A
2  (1/60) Image Only N/A
2  (1/505)  (2/3) N/A
2  (1/506)  (2/3)  Wholemount images
2  (1/505)  (2/3) N/A
2  (1/505) N/A
2  (1/505)  (2/3) N/A
2  (1/505) N/A
2  (1/61) Image Only N/A
2  (1/59)  (2/2) N/A
2  (1/505) N/A
2  (5/505)  (2/3) N/A
2  (1/505)  (2/3) N/A
2  (6/505)  (2/3) N/A
2  (1/505) N/A
2  (1/503) N/A
2  (1/503) Image Only N/A
2  (1/505)  (2/3) N/A
2  (1/505) N/A
2  (1/505)  (2/3) N/A
2  (1/75) N/A
2  (1/503) Image Only N/A
2  (1/505) Image Only N/A
2  (1/72)  (2/3) N/A
2  (1/505)  (2/3) N/A
2  (1/505) Image Only N/A

 Associated Images

Adult LacZ: LacZ Images Section
37 Images
X-ray: XRay Images Whole Body Dorso Ventral
9 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
9 Images
X-ray: XRay Images Forepaw
9 Images
Embryo LacZ: LacZ images wholemount
12 Images
X-ray: XRay Images Whole Body Lateral Orientation
9 Images
X-ray: XRay Images Skull Lateral Orientation
9 Images

 Disease Models

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 Order Mouse and ES Cells

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MGI Allele Allele Type Produced
Stxbp1tm26688(L1L2_gt0) Targeting vectors
Stxbp1tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells
Stxbp1tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Stxbp1tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice

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