Gene: Stxbp1

Name
syntaxin binding protein 1
MGI ID
MGI:107363
Synonyms
N-sec1 nsec1 Munc18-1 Unc18h Rb-sec1 Sxtbp1 Munc-18a
Viability
Homozygous - Lethal
Other links
View data by physiological system
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal behavioral response to light Stxbp1tm1b(EUCOMM)Hmgu HET postnatal 2.59×10-07
abnormal behavior Stxbp1tm1b(EUCOMM)Hmgu HET postnatal 1.19×10-06
preweaning lethality, complete penetrance Stxbp1tm1b(EUCOMM)Hmgu HOM n/a 0.00
increased bone mineral content Stxbp1tm1b(EUCOMM)Hmgu HET postnatal 4.40×10-05

Download data as:  TSV  XLS

Filtered by: all phenotypes

 Expression

IMPC lacZ Expression Data

 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens HOM Images? WT Expr Mutant Expr Images
Adrenal gland 2 No  (2/584)  (2/2)  Section images
Aorta 2 No  (2/2)  Section images
Brain 2 No  (2/2)  Section images
Brainstem 2 No  (2/2)  Section images
Brown adipose tissue 2 No N/A
Cartilage tissue 2 No  (2/2)  Section images
Cerebellum 2 No  (2/2)  Section images
Cerebral cortex 2 No  (2/2)  Section images
Epididymis 2 No  (18/134)  (1/2)  Section images
Esophagus 2 No  (7/415)  (2/2)  Section images
Eye 2 No  (2/2)  Section images
Heart 2 No  (2/2)  Section images
Hippocampus 2 No  (2/2)  Section images
Hypothalamus 2 No  (2/2)  Section images
Kidney 2 No  (18/584)  (2/2)  Section images
Large intestine 2 No  (10/584)  (2/2)  Section images
Liver 2 No N/A
Lower urinary tract 2 No N/A
Lung 2 No  (2/2)  Section images
Lymph node 2 No N/A
Mammary gland 2 No  (1/2)  Section images
Midbrain 2 No  (2/2)  Section images
Olfactory lobe 2 No  (2/2)  Section images
Ovary 2 No  (1/584)  (1/2)  Section images
Oviduct 2 No  (1/2)  Section images
Pancreas 2 No  (5/584)  (2/2)  Section images
Peripheral nervous system 2 No  (2/2)  Section images
Peyer's patch 2 No N/A
Pituitary gland 2 No  (2/2)  Section images
Prostate gland 2 No  (12/584) N/A
Skeletal muscle 2 No N/A
Skin 2 No N/A
Small intestine 2 No  (9/584)  (2/2)  Section images
Spinal cord 2 No  (2/2)  Section images
Spleen 2 No  (2/584)  (2/2)  Section images
Stomach 2 No  (12/584)  (2/2)  Section images
Striatum 2 No  (2/2)  Section images
Submandibular gland 2 No  (2/132)  (1/2)  Section images
Testis 2 No  (2/584)  (1/2)  Section images
Thalamus 2 No  (2/2)  Section images
Thymus 2 No  (2/2)  Section images
Thyroid gland 2 No  (15/584)  (2/2)  Section images
Trachea 2 No N/A
Urinary bladder 2 No  (2/2)  Section images
Uterus 2 No  (1/2)  Section images
Vascular system 2 No  (2/2)  Section images
Vesicular gland 2 No N/A
White adipose tissue 2 No N/A
 Expression  No Expression  Ambiguous  No Tissue Available
Anatomy #HET Specimens WT Expr Mutant Expr Images
Brain 2  (6/485)  (2/3) N/A
Central nervous system ganglion 2  (1/51)  (2/2) N/A
Dorsal root ganglion 2  (1/47) Image Only N/A
Ear 2  (1/485)  (2/3) N/A
Embryo 2  (1/485)  (2/3)  Wholemount images
Eye 2  (1/485)  (2/3) N/A
Foot 2  (1/485) N/A
Forebrain 2  (1/485)  (2/3) N/A
Forelimb 2  (1/485) N/A
Fronto-nasal process 2  (1/48) Image Only N/A
Gut 2  (1/50)  (2/2) N/A
Hand 2  (1/485) N/A
Head 2  (5/485)  (2/3) N/A
Heart 2  (1/485)  (2/3) N/A
Hindbrain 2  (6/485)  (2/3) N/A
Hindlimb 2  (1/485) N/A
Liver 2  (1/485) N/A
Lung 2  (1/485) Image Only N/A
Mandibular process 2  (1/485)  (2/3) N/A
Maxillary process 2  (1/485) N/A
Midbrain 2  (1/485)  (2/3) N/A
Nose 2  (1/51) N/A
Oral cavity 2  (1/485) Image Only N/A
Skin 2  (1/485) Image Only N/A
Spinal cord 2  (1/50)  (2/3) N/A
Tail 2  (1/485)  (2/3) N/A
Tail somite 2  (1/485) Image Only N/A

 Associated Images

Original Image
Adult LacZ: LacZ Images Section
37 Images
X-ray: XRay Images Skull Lateral Orientation
9 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
9 Images
Embryo LacZ: LacZ images wholemount
12 Images
X-ray: XRay Images Dorso Ventral
9 Images
X-ray: XRay Images Lateral Orientation
9 Images
X-ray: XRay Images Forepaw
9 Images
Combined SHIRPA and Dysmorphology
2 Images

 Disease Models

Please visit the desktop version to see this section

 Order Mouse and ES Cells

MGI Allele Allele Type Availability
Stxbp1tm1a(EUCOMM)Hmgu KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Stxbp1tm1b(EUCOMM)Hmgu Reporter-tagged deletion allele (post-Cre) Mice
Stxbp1tm1(KOMP)Vlcg Reporter-tagged deletion allele (with selection cassette) Targeting vectors, ES Cells
Stxbp1tm26688(L1L2_gt0) Targeting vectors

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter