Hmx2 | H6 homeobox 2

GeneMGI:107159Synonyms: Nkx5-2

Physiological systems

21 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Growth/size/body region Hearing/vestibular/ear Skeleton Mortality/aging Renal/urinary system

16 No significant impact

3 Not tested

Gene metrics:13Significant phenotypes
0Associated diseases
Expression examined in:73Adult tissues
0Embryo tissues

Phenotypes

abnormal kidney morphology2 supporting datasetsHmx2tm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
enlarged kidney2 supporting datasetsHmx2tm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
polycystic kidney2 supporting datasetsHmx2tm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
increased bone mineral content1 supporting datasetHmx2tm1.1(KOMP)VlcghomozygoteEarly adult4.03x10-5 
abnormal auditory brainstem response1 supporting datasetHmx2tm1.1(KOMP)VlcghomozygoteEarly adult7.19x10-5 
preweaning lethality, incomplete penetrance1 supporting datasetHmx2tm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
increased kidney weight1 supporting datasetHmx2tm1.1(KOMP)VlcghomozygoteEarly adult8.88x10-41 
* Does not have a P-value assigned because it was manually marked as significant.
Download data as:  










* This parameter was manually assessed for significance.
Download data as:  

lacZ Expression

Associated images

Loading...

Histopathology

IMPC related publications

Loading...

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

Hmx2tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Hmx2tm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Hmx2tm100694(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter