Hmx2 | H6 homeobox 2
Physiological systems
21 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Growth/size/body region Hearing/vestibular/ear Skeleton Mortality/aging Renal/urinary system
16 No significant impact
3 Not tested
Data collections
Gene metrics:13Significant phenotypes
0Associated diseases
Expression examined in:73Adult tissues
0Embryo tissues
abnormal kidney morphology | 2 supporting datasets | Hmx2tm1.1(KOMP)Vlcg | homozygote | Early adult | N/A * | ||
enlarged kidney | 2 supporting datasets | Hmx2tm1.1(KOMP)Vlcg | homozygote | Early adult | N/A * | ||
polycystic kidney | 2 supporting datasets | Hmx2tm1.1(KOMP)Vlcg | homozygote | Early adult | N/A * | ||
increased bone mineral content | 1 supporting dataset | Hmx2tm1.1(KOMP)Vlcg | homozygote | Early adult | 4.03x10-5 | ||
abnormal auditory brainstem response | 1 supporting dataset | Hmx2tm1.1(KOMP)Vlcg | homozygote | Early adult | 7.19x10-5 | ||
preweaning lethality, incomplete penetrance | 1 supporting dataset | Hmx2tm1.1(KOMP)Vlcg | homozygote | Early adult | N/A * | ||
increased kidney weight | 1 supporting dataset | Hmx2tm1.1(KOMP)Vlcg | homozygote | Early adult | 8.88x10-41 |
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External links
No external links available for Hmx2.
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Hmx2tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell mouse |
Hmx2tm1.1(KOMP)Vlcg | Reporter-tagged deletion allele (post Cre, with no selection cassette) | | mouse |
Hmx2tm100694(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |