Gene: Abi2

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Name
abl-interactor 2
MGI ID
MGI:106913
Synonyms
8430425M24Rik
Embryo viewer
N/A
Other links
Significant
Not Significant
Not tested
Phenotype System Allele Zyg Sex Life Stage P Value
abnormal iris pigmentation Abi2tm1b(EUCOMM)Wtsi HOM Early adult 3.26×10-16
hypoactivity Abi2tm1b(EUCOMM)Wtsi HOM Early adult 4.51×10-07
small testis Abi2tm1b(EUCOMM)Wtsi HOM Early adult 0.00
abnormal iris morphology Abi2tm1b(EUCOMM)Wtsi HOM Early adult 8.66×10-15
abnormal seminal vesicle morphology Abi2tm1b(EUCOMM)Wtsi HOM Early adult 0.00
abnormal behavior Abi2tm1b(EUCOMM)Wtsi HOM Early adult 1.34×10-07
absent urinary bladder Abi2tm1b(EUCOMM)Wtsi HOM Early adult 0.00
abnormal cornea morphology Abi2tm1b(EUCOMM)Wtsi HOM Early adult 8.16×10-15

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Viewing: all phenotypes

 Expression

Expression data not available

 Associated Images

Histopathology
13 Images
X-ray: XRay Images Whole Body Lateral Orientation
10 Images
X-ray: XRay Images Skull Dorso Ventral Orientation
10 Images
Gross Pathology and Tissue Collection
8 Images
Eye Morphology: Images Ophthalmoscopy
8 Images
Eye Morphology: Images Slit Lamp
18 Images
X-ray: XRay Images Whole Body Dorso Ventral
10 Images
X-ray: XRay Images Skull Lateral Orientation
10 Images

 Disease Models

No associations by disease annotation and gene orthology found.
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 Histopathology

Phenotype Allele Zygosity Sex Life Stage
Eye with optic nerve - developmental dysplasia Abi2tm1b(EUCOMM)Wtsi HOM Early adult
Testes - process of degenerative change Abi2tm1b(EUCOMM)Wtsi HOM Early adult
Epididymis - growth and differentiation defect Abi2tm1b(EUCOMM)Wtsi HOM Early adult

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MGI Allele Allele Type Produced
Abi2tm1a(EUCOMM)Wtsi KO first allele (reporter-tagged insertion with conditional potential) Mice, Targeting vectors, ES Cells
Abi2tm1b(EUCOMM)Wtsi Reporter-tagged deletion allele (post-Cre) Mice, Tissue

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